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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang
收藏  |  浏览/下载:61/0  |  提交时间:2022/01/18
Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:  Zou, Hui-xi;  Zhang, Yu-feng;  Zhong, Da-fang;  Jiang, Yong;  Liu, Fei
收藏  |  浏览/下载:18/0  |  提交时间:2022/01/04
Structural insights into ligand recognition and activation of the melanocortin-4 receptor 期刊论文
CELL RESEARCH, 2021, 页码: 13
作者:  Zhang, Huibing;  Chen, Li-Nan;  Yang, Dehua;  Mao, Chunyou;  Shen, Qingya
收藏  |  浏览/下载:33/0  |  提交时间:2021/11/04
Design and Synthesis of Alkyl Phenols Inhibitors of Death Associated Apoptotic Protein Kinase 2 (DRAK2) 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3204-3213
作者:  Zheng Zhang;  Dai Chengqiu;  Wu Honghong;  Li Jingya
收藏  |  浏览/下载:19/0  |  提交时间:2021/11/04
Structurally diverse diterpenoid alkaloids from the lateral roots of Aconitum carmichaelii Debx. and their anti-tumor activities based on in vitro systematic evaluation and network pharmacology analysis 期刊论文
RSC ADVANCES, 2021, 卷号: 11, 期号: 43, 页码: 26594-26606
作者:  Yu, Yang;  Wu, Shifei;  Zhang, Jianqing;  Li, Jiayuan;  Yao, Changliang
收藏  |  浏览/下载:27/0  |  提交时间:2021/11/04
Discovery of Cyclic Peptidomimetic Ligands Targeting the Extracellular Domain of EGFR 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 11219-11228
作者:  Zheng, Mengmeng;  Li, Chunpu;  Zhou, Mi;  Jia, Ru;  Cai, Gang
收藏  |  浏览/下载:64/0  |  提交时间:2021/11/04
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng
收藏  |  浏览/下载:45/0  |  提交时间:2021/08/17
Dysregulation of ClpP by Small-Molecule Activators Used Against Xanthomonas oryzae pv. oryzae Infections 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 27, 页码: 7545-7553
作者:  Yang, Teng;  Zhang, Tao;  Zhou, Xiang;  Wang, Pengyu;  Gan, Jianhua
收藏  |  浏览/下载:76/0  |  提交时间:2021/08/17
Identification of novel anti-inflammatory Nur77 modulators by virtual screening 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 7
作者:  Ding, Xiaoyu;  Zhao, Zijie;  Wu, Yue;  Zhang, Hao;  Chen, Kaixian
收藏  |  浏览/下载:44/0  |  提交时间:2021/08/17
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens
收藏  |  浏览/下载:73/0  |  提交时间:2021/08/17


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