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科研机构
上海药物研究所 [14]
过程工程研究所 [2]
合肥物质科学研究院 [2]
兰州化学物理研究所 [2]
新疆理化技术研究所 [1]
内容类型
期刊论文 [21]
发表日期
2021 [21]
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A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11
作者:
Cheng, Zhiyang
;
Huang, Ying
;
Shen, Qianqian
;
Zhao, Yangrong
;
Wang, Lei
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/11/04
Cancer
beta-glucuronidase
Bioconjugation
Albumin
Camptothecin
SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 339, 页码: 297-306
作者:
Huang, Ying
;
Wang, Lei
;
Cheng, Zhiyang
;
Yang, Biyu
;
Yu, Jiahui
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/12/01
Antitumour
Chemotherapy
SN38
Drug delivery systems
Albumin
Prodrug nanoparticles rationally integrating stroma modification and chemotherapy to treat metastatic pancreatic cancer
期刊论文
BIOMATERIALS, 2021, 卷号: 278
作者:
Wang, Liying
;
Liu, Zimo
;
Zhou, Quan
;
Gu, Sufang
;
Liu, Xiangsheng
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/11/29
Pancreatic cancer
Polymeric prodrug
Calcipotriol
Cancer-associated fibroblast
Metastasis
Noncovalent theranostic prodrug for hypoxia activated drug delivery and real-time tracking
期刊论文
Analytical Chemistry, 2021, 期号: 93, 页码: 15080-15087
作者:
Xiao-Bo Zhao (赵晓博)
;
Kun Gao (高坤)
;
Yan-Ping Shi (师彦平)
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/11/18
Genetically-engineered "all-in-one" vaccine platform for cancer immunotherapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 11, 页码: 3622-3635
作者:
Wu, Aihua
;
Chen, Yingzhi
;
Wang, Hairui
;
Chang, Ya
;
Zhang, Meng
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  |  
浏览/下载:24/0
  |  
提交时间:2022/01/18
Trichosanthin
Legumain
TRP2
Transcutaneous immunization
Adjuvant
Cancer vaccine
Protein engineering
A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
Lipophilic Conjugates of Drugs: A Tool to Improve Drug Pharmacokinetic and Therapeutic Profiles
期刊论文
PHARMACEUTICAL RESEARCH, 2021, 页码: 22
作者:
Han, Sifei
;
Mei, Lianghe
;
Quach, Tim
;
Porter, Chris
;
Trevaskis, Natalie
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  |  
浏览/下载:34/0
  |  
提交时间:2021/11/04
conjugate
lipid
lymphatic
pharmacokinetics
prodrug
Engineering Chameleon Prodrug Nanovesicles to Increase Antigen Presentation and Inhibit PD-L1 Expression for Circumventing Immune Resistance of Cancer
期刊论文
ADVANCED MATERIALS, 2021, 页码: 12
作者:
Zhou, Fengqi
;
Gao, Jing
;
Tang, Yang
;
Zou, Zhifeng
;
Jiao, Shi
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/11/04
antigen presentation
autophagy inhibition
immune resistance
immunotherapy
prodrug nanovesicles
Enzyme-Activated Prodrug-Based Smart Liposomes Specifically Enhance Tumor Hemoperfusion with Efficient Drug Delivery to Pancreatic Cancer Cells and Stellate Cells
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2021, 页码: 14
作者:
Duan, Nianxiu
;
Li, Junjun
;
Song, Sha
;
Wang, Feng
;
Yang, Yiwei
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/11/04
drug delivery
pancreatic cancer
prodrugs
smart liposomes
tumor-specific vascular promotion
Preparation of mesoporous silica nanoparticle with tunable pore diameters for encapsulating and slowly releasing eugenol
期刊论文
CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 5, 页码: 1755-1758
作者:
Zhang, Tianlu
;
Lu, Zhiguo
;
Wang, Jianze
;
Shen, Jie
;
Hao, Qiulian
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/08/31
Eugenol
Mesoporous silica nanoparticles
Nano-fragrance
Slow release of fragrance
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