×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
复旦大学上海医学院 [12]
山东大学 [10]
中国医学科学院 北京... [6]
上海药物研究所 [5]
武汉大学 [5]
吉林大学白求恩第三医... [4]
更多...
内容类型
期刊论文 [67]
发表日期
2019 [67]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共67条,第1-10条
帮助
限定条件
发表日期:2019
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204
作者:
Zhou, Ting-ting
;
Zhao, Tong
;
Ma, Fei
;
Zhang, Yi-nan
;
Jiang, Jing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
type 2 diabetes mellitus
hepatic gluconeogenesis
AMPK signaling pathway
(E)-3-(2-(quinoline-4-yl)vinyl)-1H-indol-6-ol (QVO)
4-[2-(1H-indol-3-yl)vinyl]quinoline (IVQ)
prodrug
Saxagliptin alters bile acid profiles and yields metabolic benefits in drug-naive overweight or obese type 2 diabetes patient
期刊论文
JOURNAL OF DIABETES, 2019, 页码: 11
作者:
Li, Wen
;
Liu, Ruixin
;
Li, Xuelin
;
Tao, Bei
;
Zhai, Nan
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2019/12/02
bile acids
dipeptidyl peptidase-4 inhibitor
obesity
saxagliptin
type 2 diabetes
Characterization of drug-drug salt forms of metformin and aspirin with improved physicochemical properties
期刊论文
CRYSTENGCOMM, 2019, 卷号: 21, 期号: 25, 页码: 3770-3773
作者:
Zhou, Wen-Xiu
;
Zhao, Hong-Wei
;
Chen, Huan-Huan
;
Zhang, Zai-Yong
;
Chen, Dong-Ying
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:
Wang, Fang
;
Yang, Xiaoyan
;
Lu, Yanting
;
Li, Zhenghui
;
Xu, Yuhui
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2019/09/10
glucose metabolism
liver kinase B1 (LKB1)
AMP-activated kinase (AMPK)
glucose transporter type 4 (GLUT4)
fungi
Basidiomycete
diabetes
energy sensing
glucose homeostasis
sesquiterpene
Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene
期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 13
作者:
Han, Yamei
;
Hu, Zhimin
;
Cui, Aoyuan
;
Liu, Zhengshuai
;
Ma, Fengguang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Metabolomics profiling of metformin-mediated metabolic reprogramming bypassing AMPK alpha
期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2019, 卷号: 91, 页码: 18-29
作者:
Yan, Min
;
Qi, Huan
;
Xia, Tian
;
Zhao, Xinjie
;
Wang, Wen
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2019/07/26
Metformin
Ampk
Metabolomics
Metabolic flux
Independence
Enhanced Anti-diabetic Effect of Berberine Combined With Timosaponin B2 in Goto-Kakizaki Rats, Associated With Increased Variety and Exposure of Effective Substances Through Intestinal Absorption
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 15
作者:
Tian, Xiaoting
;
Liu, Fang
;
Li, Zhixiong
;
Lin, Yunfei
;
Liu, Huan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
berberine
timosaponin B2
diabetes
combination treatments
drug-drug interaction
metabolites
hepatic metabolism
intestinal absorption
Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 3, 页码: 953-967
作者:
Yan, Yan
;
Zhou, X. Edward
;
Novick, Scott J.
;
Shaw, Simon J.
;
Li, Yingwu
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
AMP-activated kinase (AMPK)
AMP
hydrogen exchange mass spectrometry
X-ray crystallography
phosphorylation
activation loop phosphorylation
ADaM site
CBS3
R734
R739
metabolic disorder
energy sensor
Metformin promotes survivin degradation through AMPK/PKA/GSK-3-axis in non-small cell lung cancer
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 期号: 7
作者:
Zhu, Tingting
;
Luo, Zhuang
;
Chen, Wei
;
Wu, Wenjuan
;
Luo, Wei
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/04
adenosine 5-monophosphate-activated protein kinase
glycogen synthase kinase 3
metformin
non-small cell lung cancer
survivin
Combinational effect of curcumin and metformin against gentamicin-induced nephrotoxicity: Involvement of antioxidative, anti-inflammatory and antiapoptotic pathway
期刊论文
JOURNAL OF FOOD BIOCHEMISTRY, 2019, 卷号: 43, 期号: 7
作者:
Cao, Liying
;
Zhi, Dongyun
;
Han, Jing
;
Sah, Sushil Kumar
;
Xie, Yunhui
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/04
apoptosis
curcumin
gentamicin
metformin
nephrotoxicity
oxidative stress
©版权所有 ©2017 CSpace - Powered by
CSpace