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Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204
作者:  Zhou, Ting-ting;  Zhao, Tong;  Ma, Fei;  Zhang, Yi-nan;  Jiang, Jing
收藏  |  浏览/下载:22/0  |  提交时间:2020/07/01
Saxagliptin alters bile acid profiles and yields metabolic benefits in drug-naive overweight or obese type 2 diabetes patient 期刊论文
JOURNAL OF DIABETES, 2019, 页码: 11
作者:  Li, Wen;  Liu, Ruixin;  Li, Xuelin;  Tao, Bei;  Zhai, Nan
收藏  |  浏览/下载:72/0  |  提交时间:2019/12/02
Characterization of drug-drug salt forms of metformin and aspirin with improved physicochemical properties 期刊论文
CRYSTENGCOMM, 2019, 卷号: 21, 期号: 25, 页码: 3770-3773
作者:  Zhou, Wen-Xiu;  Zhao, Hong-Wei;  Chen, Huan-Huan;  Zhang, Zai-Yong;  Chen, Dong-Ying
收藏  |  浏览/下载:7/0  |  提交时间:2020/07/01
The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui
收藏  |  浏览/下载:74/0  |  提交时间:2019/09/10
Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 13
作者:  Han, Yamei;  Hu, Zhimin;  Cui, Aoyuan;  Liu, Zhengshuai;  Ma, Fengguang
收藏  |  浏览/下载:19/0  |  提交时间:2020/07/01
Metabolomics profiling of metformin-mediated metabolic reprogramming bypassing AMPK alpha 期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2019, 卷号: 91, 页码: 18-29
作者:  Yan, Min;  Qi, Huan;  Xia, Tian;  Zhao, Xinjie;  Wang, Wen
收藏  |  浏览/下载:64/0  |  提交时间:2019/07/26
Enhanced Anti-diabetic Effect of Berberine Combined With Timosaponin B2 in Goto-Kakizaki Rats, Associated With Increased Variety and Exposure of Effective Substances Through Intestinal Absorption 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 15
作者:  Tian, Xiaoting;  Liu, Fang;  Li, Zhixiong;  Lin, Yunfei;  Liu, Huan
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/01
Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 3, 页码: 953-967
作者:  Yan, Yan;  Zhou, X. Edward;  Novick, Scott J.;  Shaw, Simon J.;  Li, Yingwu
收藏  |  浏览/下载:13/0  |  提交时间:2020/07/01
Metformin promotes survivin degradation through AMPK/PKA/GSK-3-axis in non-small cell lung cancer 期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 期号: 7
作者:  Zhu, Tingting;  Luo, Zhuang;  Chen, Wei;  Wu, Wenjuan;  Luo, Wei
收藏  |  浏览/下载:21/0  |  提交时间:2019/12/04
Combinational effect of curcumin and metformin against gentamicin-induced nephrotoxicity: Involvement of antioxidative, anti-inflammatory and antiapoptotic pathway 期刊论文
JOURNAL OF FOOD BIOCHEMISTRY, 2019, 卷号: 43, 期号: 7
作者:  Cao, Liying;  Zhi, Dongyun;  Han, Jing;  Sah, Sushil Kumar;  Xie, Yunhui
收藏  |  浏览/下载:26/0  |  提交时间:2019/12/04


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