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科研机构
上海药物研究所 [796]
内容类型
期刊论文 [782]
会议论文 [13]
项目 [1]
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2021 [43]
2020 [42]
2019 [37]
2018 [48]
2017 [46]
2016 [54]
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Chemistry [62]
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共796条,第1-10条
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Spatial lipidomics of eight edible nuts by desorption electrospray ionization with ion mobility mass spectrometry imaging
期刊论文
FOOD CHEMISTRY, 2022, 卷号: 371, 页码: 11
作者:
Hou, Jinjun
;
Zhang, Zijia
;
Zhang, Linlin
;
Wu, Wenyong
;
Huang, Yong
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2021/12/16
Desorption electrospray ionization (DESI)
Mass spectrometry imaging (MSI)
Ion mobility
Collision cross section (CCS)
Nuts
Phospholipids
Fatty acid derivatives
Distribution profiles
Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Huangjinsan ameliorates adenine-induced chronic kidney disease by regulating metabolic profiling
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 11
作者:
Guo, Yuejiao
;
Liu, Fang
;
Chen, MingCang
;
Tian, Qiang
;
Tian, Xiaoting
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/12/16
chronic kidney disease
Huangjinsan
metabolomics
renoprotection
traditional Chinese medicine
A simultaneous identification and quantification strategy for determination of sulfhydryl-containing metabolites in normal- and high-fat diet hamsters using stable isotope labeling combined with LC-MS
期刊论文
ANALYTICA CHIMICA ACTA, 2021, 卷号: 1184, 页码: 13
作者:
Chang, Lu
;
Lin, Feifei
;
Cheng, Kai
;
Li, Jiaomeng
;
Sun, Xiaochu
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/01/18
Sulfhydryl-containing metabolites
Stable isotope labeling
Identification
Quantification
Hyperlipidemia
Oxidative stress
GADD45 beta stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 173, 页码: 11
作者:
Dong, Yunxia
;
Ma, Ningning
;
Fan, Lei
;
Yuan, Luyang
;
Wu, Qian
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/12/16
Non-alcoholic fatty liver disease
GADD45 beta
HSP72
Lipid accumulation
Insulin resistance
Untargeted metabolomics coupled with chemometric analysis deducing robust markers for discrimination of processing procedures: Wine-processed Angelica sinensis as a case study
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 19
作者:
Yin, Haoran
;
Ni, Hui
;
Zhang, Linlin
;
Wu, Wenyong
;
Wu, Xingdong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/01
Angelica sinensis
processing procedures
traditional Chinese medicine
untargeted metabolomics
wine-processing markers
A five-dimensional data collection strategy for multicomponent discovery and characterization in Traditional Chinese Medicine: Gastrodia Rhizoma as a case study
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2021, 卷号: 1653, 页码: 12
作者:
Zhu, Haodong
;
Wu, Xingdong
;
Huo, Jiangyan
;
Hou, Jinjun
;
Long, Huali
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2021/11/04
Gastrodia Rhizoma
Multidimensional data acquisition
Offline 2D-LC-IMS-DIA MS
MS
Neutral loss (NLs)
Collision cross section (CCS)
A validated HPLC-MS/MS method for determination of simmitecan and its metabolite chimmitecan in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 8
作者:
Zhou, Jun
;
Zhan, Yan
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Zhang, Yifan
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2021/11/04
chimmitecan
mass spectrometry
pharmacokinetics
simmitecan
solid tumors
Comprehensively feature-based molecular networking and metabolomics approaches to reveal the differences components in Cinnamomum cassia and Cinnamomum verum
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 12
作者:
Wu, Xingdong
;
Long, Huali
;
Li, Feifei
;
Wu, Wenyong
;
Zhou, Jing
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/11/04
alkaloids
Cinnamomum
feature-based molecular networking
metabolite profiling
proanthocyanidins
Restoring perturbed oxylipins with Danqi Tongmai Tablet attenuates acute myocardial infarction
期刊论文
PHYTOMEDICINE, 2021, 卷号: 90, 页码: 12
作者:
Zhi, Haijuan
;
Zhang, Zijia
;
Deng, Yanping
;
Yan, Bingpeng
;
Li, Zhenwei
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/11/04
Acute myocardial infarction
Danqi Tongmai tablet
In vivo metabolite
Oxylipin
Arachidonic acid metabolome
Homeostasis
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