×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
复旦大学上海医学院 [3]
成都中医药大学 [3]
四川大学 [2]
中南大学 [2]
江苏大学 [1]
上海药物研究所 [1]
更多...
内容类型
期刊论文 [11]
学位论文 [1]
发表日期
2016 [12]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共12条,第1-10条
帮助
限定条件
发表日期:2016
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 67071-67086
作者:
Qian, Jianchang
;
Chen, Yaqing
;
Meng, Tao
;
Ma, Lanping
;
Meng, Lanfang
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
mTOR kinase inhibitor
mTORC2
apoptosis
lipid metabolism
Rictor/mTORC2 loss in osteoblasts impairs bone mass and strength
期刊论文
BONE, 2016, 卷号: 90
作者:
Liu, Dong-mei
;
Zhao, Lin
;
Liu, Ting-ting
;
Jiao, Pei-lin
;
Zhao, Dian-dian
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Rictor
mTORC2
Osteoblasts
Osteoclasts
Bone remodeling
mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 18
作者:
Chen, Yaqing
;
Qian, Jianchang
;
He, Qun
;
Zhao, Hui
;
Toral-Barza, Lourdes
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
mTORC2
ATP citrate lyase
lipid synthesis
breast cancer
cancer metabolism
microRNA-153 Targets mTORC2 Component Rictor to Inhibit Glioma Cells
期刊论文
PLOS ONE, 2016, 卷号: 11, 期号: 6, 页码: e0156915
作者:
Cui, Yan
;
Zhao, Jizong
;
Yi, Lei
;
Jiang, Yugang*
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
Glioma cells,Glioma,Apoptosis,MTT assay,Astrocytes,Polymerase chain reaction,MicroRNAs,Cell growth
Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells
期刊论文
Cellular Signalling, 2016, 卷号: 28, 期号: 8, 页码: 1099-1104
作者:
Wang, Jing
;
Yang, Xin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/03
4E-BP1
4E binding protein
AMPK
AMP-activated protein kinase
ATF6
activating transcription factor 6
ATP
adenosine triphosphate
DEPTOR
DEP domain containing mTOR-interacting protein
CI
complexes I
CII
complex II
CIII
complex III
CIV
complex IV
CV
complex V
eIF2α
Eukaryotic Initiation Factor 2α
ER
Endoplasmic Reticulum
ERAD
ER-associated degradation
ERO1α
ER oxidoreductase 1 α
FoxO1
Forkhead box O1
GβL
G Protein β Subunit Like Protein
GRP78
78 kDa glucose-regulated protein precursor
GSIS
glucose-stimulated insulin secretion
IRE1
Inositol-requiring enzyme 1
IRS1
Insulin receptor substrate 1
IRS2
Insulin receptor substrate 2
mLST8
mammalian lethal with sec-13 protein 8
mSin1
the mammalian stress-activated MAP kinase-interaction protein 1
mtDNA
mitochondrial deoxyribonucleic acid
mTOR
mammalian TOR
mTORC1
mTOR complex 1
mTORC2
mTOR complex 2
NADPH oxidase
Nicotinamide adenine dinucleotide phosphate-oxidase
NOS
nitric oxide synthase
O2–·
superoxide anion
H2O2
hydrogen peroxide
OH·
hydroxyl radical
3O2
triplet-state molecular oxygen
OXPHOS
oxidative phosphorylation
CAT
catalase
GPx
glutathioneperoxidase
PERK
Protein kinase R-like endoplasmic reticulum kinase
PDI
ER protein disulfide isomerases
PI3K
the phosphoinositide3-kinase
PRAS40
40-kDa proline-rich Akt substrate
PRAS40
the 40-kDa proline-rich Akt substrate
PROTOR
the protein observed with RICTOR
RAPTOR
regulatory-associated protein of mTOR
RICTOR
The rapamycin-insensitive companion of mTOR
REDD1
DNA damage response 1
RNS
reactive nitrogen species
ROS
reactive oxygen species
RNS
reactive nitrogen species
S6K
S6 kinase
SOD
superoxidedismutase
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TOR
the target of rapamycin
TSC2
Tuberous sclerosis 2
UPR
unfolded protein response
Mitochondrial oxidative stress
ER stress
mTOR
Pancreatic β cells
mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR
期刊论文
Cell Research, 2016, 卷号: Vol.26 No.1, 页码: 46-65
作者:
Yin, Y.
;
Hua, H.
;
Li, M.
;
Liu, S.
;
Kong, Q.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/02/25
insulin
receptor
insulin-like
growth
factor
receptor
mTOR
mTORC2
protein
kinase
AMPK-mediated up-regulation of mTORC2 and MCL-1 compromises the anti-cancer effects of aspirin
期刊论文
Oncotarget, 2016, 卷号: Vol.7 No.13, 页码: 16349-16361
作者:
Gao, M.
;
Kong, Q.
;
Hua, H.
;
Yin, Y.
;
Wang, J.
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/02/25
Amp-activated
protein
kinase
Aspirin
Drug
resistance
Experimental
cancer
therapy
MCL-1
mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR
期刊论文
2016, 卷号: 0, 期号: 1, 页码: 46-65
作者:
YancunYin[1]
;
Hui Hua[2]
;
Minjing Li[3]
;
Shu Liu[1]
;
Qingbin Kong[1]
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/16
胰岛素样生长因子
胰岛素受体底物
酪氨酸磷酸化
mTOR
激酶活性
激活
IGF-IR
R蛋白
Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41
作者:
Qian, Jianchang
;
Chen, Yaqing
;
Meng, Tao
;
Ma, Lanping
;
Meng, Lanfang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/13
mTOR kinase inhibitor
mTORC2
apoptosis
lipid metabolism
APC/C~(Cdc20)对G2/M期Akt活性的调控作用
学位论文
: 江苏大学, 2016
作者:
孙玲先[1]
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/24
G2/M期
同步化
Akt
APC/C
mTORC2
Cdh1
Cdc20
©版权所有 ©2017 CSpace - Powered by
CSpace