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科研机构
上海药物研究所 [109]
内容类型
期刊论文 [108]
会议论文 [1]
发表日期
2021 [8]
2020 [6]
2019 [7]
2018 [6]
2017 [7]
2016 [3]
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Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14
作者:
Zhang, Chun
;
Sun, Yi-Tao
;
Gao, Li-Xin
;
Feng, Bo
;
Yan, Xue
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/01/18
Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation
期刊论文
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:
Li, Heng
;
Zhang, Xianglei
;
Xiang, Caigui
;
Feng, Chunlan
;
Fan, Chen
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/11/04
PDE4
Arctigenin
Psoriasis
Inflammation
Synthesis and Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitory Activity Evaluation of Novel N-Acylhydrazone Derivatives Containing Carbazole and Aromatic Ring/Aromatic Fused Heterocycle
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 9, 页码: 3593-3607
作者:
Li Yingjun
;
Lin Ledi
;
Liu Jihong
;
Gao Lixin
;
Sheng Li
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/12/01
PTP1B inhibitor
carbazole
N-actylhydrazone
synthesis
molecular docking
ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 9
作者:
Chen, Yuning
;
Zhang, Ya-Nan
;
Yan, Renhong
;
Wang, Guifeng
;
Zhang, Yuanyuan
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/11/04
Synthesis and Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitory Activity Evaluation of Novel Arylaminoacetylhydrazone Derivatives Containing Carbazole Moiety
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3157-3170
作者:
Li Yingjun
;
Lin Ledi
;
Jin Kun
;
Gao Lixin
;
Sheng Li
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/11/04
protein tyrosine phosphatase 1B (PTP1B) inhibitor
carbazole
arylaminoacetylhydrazone
synthesis
molecular docking
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2021/08/17
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Wu, Ya-li
;
Xue, Ya-ru
;
Guo, Zi-tao
;
Chen, Zhen-dong
;
Ge, Xin-yu
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/08/17
furmonertinib (alflutinib
AST2818)
quantitative proteomics
sandwich-cultured human hepatocytes
Antibodies Against Pseudomonas aeruginosa Alkaline Protease Directly Enhance Disruption of Neutrophil Extracellular Traps Mediated by This Enzyme
期刊论文
FRONTIERS IN IMMUNOLOGY, 2021, 卷号: 12, 页码: 16
作者:
Jing, Chendi
;
Liu, Chenghua
;
Liu, Yu
;
Feng, Ruli
;
Cao, Run
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2021/05/24
Pseudomonas aeruginosa
alkaline protease
alkaline protease inhibitor
neutrophil extracellular traps
antibody-dependent enhancement
Phytochemicals from the Leaves of Cyclocarya paliurus and their 11 beta-HSD1 Enzyme Inhibitory Effects
期刊论文
CHEMISTRY & BIODIVERSITY, 2020, 页码: 7
作者:
Yan, Huan
;
Li, Xiang
;
Ni, Wei
;
Zhao, Qing
;
Leng, Ying
收藏
  |  
浏览/下载:118/0
  |  
提交时间:2021/05/24
Cyclocarya paliurus
dammarane-type triterpenoid saponins
11β
-HSD1 enzyme
inhibitory activity
Pulmonary Targeting Crosslinked Cyclodextrin Metal-Organic Frameworks for Lung Cancer Therapy
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 13
作者:
He, Yaping
;
Xiong, Ting
;
He, Siyu
;
Sun, Hongyu
;
Huang, Chenxi
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/12/21
cancer therapy
cyclodextrin frameworks
low-molecular-weight heparin
lung-targeting carriers
RGD peptide
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