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Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng
收藏  |  浏览/下载:45/0  |  提交时间:2021/08/17
Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl Inhibitor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 7, 页码: 3956-3975
作者:  Zhang, Hefeng;  Peng, Xia;  Dai, Yang;  Shao, Jingwei;  Ji, Yinchun
收藏  |  浏览/下载:16/0  |  提交时间:2021/06/11
Substitution Effect of the Trifluoromethyl Group on the Bioactivity in Medicinal Chemistry: Statistical Analysis and Energy Calculations 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2020, 卷号: 60, 期号: 12, 页码: 6242-6250
作者:  Abula, Amina;  Xu, Zhijian;  Zhu, Zhengdan;  Peng, Cheng;  Chen, Zhaoqiang
收藏  |  浏览/下载:24/0  |  提交时间:2021/05/24
SOMCL-863, a novel, selective and orally bioavailable small-molecule c-Met inhibitor, exhibits antitumor activity both in vitro and in vivo (vol 351, pg 413, 2014) 期刊论文
CANCER LETTERS, 2020, 卷号: 486, 页码: 71-72
作者:  Wang, Lu;  Ai, Jing;  Shen, Yanyan;  Zhang, Haotian;  Peng, Xia
收藏  |  浏览/下载:10/0  |  提交时间:2020/12/24
Simultaneous determination of sutetinib and its active metabolite sutetinibN-oxide in human plasma by liquid chromatography-tandem mass spectrometry: Evaluation of plasma stability 期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 9
作者:  Qiu, Yanan;  Tang, Chongzhuang;  Li, Ranran;  Cao, Sumin;  Zhang, Yuqiang
收藏  |  浏览/下载:28/0  |  提交时间:2020/12/24
Synthesis of triazolotriazine derivatives as c-Met inhibitors 期刊论文
MOLECULAR DIVERSITY, 2020, 页码: 8
作者:  Guo, Yuting;  Peng, Xia;  Ji, Yinchun;  Zhang, Yitong;  Ding, Jian
收藏  |  浏览/下载:37/0  |  提交时间:2020/12/24
Structure of formylpeptide receptor 2-G(i) complex reveals insights into ligand recognition and signaling 期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 12
作者:  Zhuang, Youwen;  Liu, Heng;  Zhou, X. Edward;  Verma, Ravi Kumar;  de Waal, Parker W.
收藏  |  浏览/下载:14/0  |  提交时间:2020/12/24
SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met 期刊论文
CANCER SCIENCE, 2019, 页码: 11
作者:  Tong, Mengya;  Gao, Mingzhao;  Xu, Yongping;  Fu, Li;  Li, Yun
收藏  |  浏览/下载:21/0  |  提交时间:2020/07/01
SHR-A1403, a novel c-Met antibody-drug conjugate, exerts encouraging anti-tumor activity in c-Met-overexpressing models 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 7, 页码: 971-979
作者:  Yang, Chang-yong;  Wang, Lei;  Sun, Xing;  Tang, Mi;  Quan, Hai-tian
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/01
Discovery of a potent tyrosine kinase AXL inhibitor bearing the 3-((2,3,4,5-tetrahydro-1H-benzo [d] azepin-7-yl)amino)pyrazine core 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 836-838
作者:  Wang, Yueliang;  Xing, Li;  Ji, Yinchun;  Ye, Jiqing;  Dai, Yang
收藏  |  浏览/下载:15/0  |  提交时间:2020/07/01


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