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科研机构
上海药物研究所 [21]
内容类型
期刊论文 [21]
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2021 [1]
2020 [1]
2018 [1]
2017 [1]
2015 [2]
2013 [4]
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Beshanzoides A-D, unprecedented cycloheptanone-containing polyketides from Penicillium commune P-4-1, an endophytic fungus of the endangered conifer Abies beshanzuensis
期刊论文
RSC ADVANCES, 2021, 卷号: 11, 期号: 63, 页码: 39781-39789
作者:
Chen, Hao-Wei
;
Jiang, Chun-Xiao
;
Li, Jiyang
;
Li, Na
;
Zang, Yi
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/01/18
AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Sun, Shui-mei
;
Xie, Zhi-fu
;
Zhang, Yang-ming
;
Zhang, Xin-wen
;
Zhou, Chen-dong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/12/24
adenosine 5 '-monophosphate-activated protein kinase
AMPK activator
C24
liver
triglycerides
cholesterol
VLDL
hypolipidemic drug
metabolic syndrome
Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2 ',3 ': 4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5 '-monophosphate-activated protein kinase (AMPK)
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2017-2027
作者:
Gu, Zhanni
;
Wu, Lingyan
;
Duan, Yanan
;
Wang, Jiang
;
Zhou, Shengbin
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
Adenosine 5 '-monophosphate-activated protein kinase
AMPK activators
Berberine
Tetrahydroberberine
T2DM
Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 期号: 30, 页码: 12653-12666
作者:
Gu, Xin
;
Yan, Yan
;
Novick, Scott J.
;
Kovach, Amanda
;
Goswami, Devrishi
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
AMP
AMP-activated kinase (AMPK)
ATP
energy metabolism
protein kinase
CBS
HDX-MS
NADPH
Yhhu981, a novel compound, stimulates fatty acid oxidation via the activation of AMPK and ameliorates lipid metabolism disorder in ob/ob mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 3, 页码: 343-352
作者:
Zeng, Hong-liang
;
Huang, Su-ling
;
Xie, Fu-chun
;
Zeng, Li-min
;
Hu, You-hong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
yhhu981
fatty acid oxidation
fatty acid synthesis
AMPK
compound C
sirtinol
EX527
STO609
AICAR
metformin
metabolism disorder
C2C12 myotubes
HepG2 cells
ob/ob mice
Structural basis of AMPK regulation by adenine nucleotides and glycogen
期刊论文
CELL RESEARCH, 2015, 卷号: 25, 期号: 1, 页码: 50-66
作者:
Li, Xiaodan
;
Wang, Lili
;
Zhou, X. Edward
;
Ke, Jiyuan
;
de Waal, Parker W.
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
AMPK
adenine nucleotides
glycogen
diabetes
Novel small-molecule AMPK activator orally exerts beneficial effects on diabetic db/db mice
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2013, 卷号: 273, 期号: 2, 页码: 325-334
作者:
Li, Yuan-Yuan
;
Yu, Li-Fang
;
Zhang, Li-Na
;
Qiu, Bei-Ying
;
Su, Ming-Bo
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
AMPK
Activator
Allosteric
Small-molecule
Orally effective
Metabolic syndrome
Latanoprost effectively ameliorates glucose and lipid disorders in db/db and ob/ob mice
期刊论文
DIABETOLOGIA, 2013, 卷号: 56, 期号: 12, 页码: 2702-2712
作者:
Wang, Gaihong
;
Xu, Xing
;
Yao, Xingang
;
Zhu, Zhiyuan
;
Yu, Liang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
AMPK
Glucose and lipid metabolism
Latanoprost
RXR alpha/PPAR gamma heterodimer
Type 2 diabetes
Danthron activates AMP-activated protein kinase and regulates lipid and glucose metabolism in vitro
期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 8, 页码: 1061-1069
作者:
Zhou, Rong
;
Wang, Ling
;
Xu, Xing
;
Chen, Jing
;
Hu, Li-hong
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
1,8-dihydroxyanthraquinone (danthron)
traditional Chinese medicine
AMPK
SREBP1c
fatty acid synthetase
cholesterol
triglyceride
glucose consumption
danthronactivatesampactivatedproteinkinaseandregulateslipidandglucosemetabolisminvitro
期刊论文
actapharmacologicasinica, 2013, 卷号: 34, 期号: 8, 页码: 1061
作者:
Zhou Rong
;
Wang Ling
;
Xu Xing
;
Chen Jing
;
Hu Lihong
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
1
8-dihydroxyanthraquinone (danthron)
traditional Chinese medicine
AMPK
SREBP1c
fatty acid synthetase
cholesterol
triglyceride
glucose consumption
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