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CORC

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Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK 期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:  Elksnis, Andris;  Schiffer, Tomas A.;  Palm, Fredrik;  Wang, Yun;  Cen, Jing
收藏  |  浏览/下载：21/0  |  提交时间：2021/12/01
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng
收藏  |  浏览/下载：45/0  |  提交时间：2021/08/17
Discovery of a potent, selective, and covalent ZAP-70 kinase inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 219, 页码: 12
作者:  Rao, Danni;  Li, Heng;  Ren, Xuelian;  Sun, Yaoliang;  Wen, Cuiyun
收藏  |  浏览/下载：28/0  |  提交时间：2021/08/17
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:  Wu, Xiaowei;  Dai, Mengdi;  Cui, Rongrong;  Wang, Yulan;  Li, Chunpu
收藏  |  浏览/下载：47/0  |  提交时间：2021/05/24
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:  Liu, Yu-ting;  Ding, Hui-hua;  Lin, Ze-min;  Wang, Que;  Chen, Li
收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:  Dai, Meng-di;  Wang, Yue-liang;  Fan, Jun;  Dai, Yang;  Ji, Yin-chun
收藏  |  浏览/下载：32/0  |  提交时间：2021/05/24
Drug interaction of ningetinib and gefitinib involving CYP1A1 and efflux transporters in non-small cell lung cancer patients 期刊论文
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 页码: 13
作者:  Liu, Lu;  Wang, Qian;  Xie, Cen;  Xi, Ning;  Guo, Zitao
收藏  |  浏览/下载：55/0  |  提交时间：2020/12/24
Characterization of covalent binding of tyrosine kinase inhibitors to plasma proteins 期刊论文
DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 35, 期号: 5, 页码: 456-465
作者:  Liu, Xiaoyun;  Feng, Dan;  Zheng, Mingyue;  Cui, Yongmei;  Zhong, Dafang
收藏  |  浏览/下载：13/0  |  提交时间：2020/12/21
Synthesis of triazolotriazine derivatives as c-Met inhibitors 期刊论文
MOLECULAR DIVERSITY, 2020, 页码: 8
作者:  Guo, Yuting;  Peng, Xia;  Ji, Yinchun;  Zhang, Yitong;  Ding, Jian
收藏  |  浏览/下载：37/0  |  提交时间：2020/12/24
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:  Lai, Meng-zhen;  Song, Pei-ran;  Dou, Dou;  Diao, Yan-yan;  Tong, Lin-jiang
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/01

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