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Deficiency of dietary niacin decreases digestion and absorption capacities via declining the digestive and brush border enzyme activities and downregulating those enzyme gene transcription related to TOR pathway of the hepatopancreas and intestine in young grass carp (Ctenopharyngodon idella) 期刊论文
AQUACULTURE NUTRITION, 2016, 卷号: 22, 期号: 6, 页码: 1267-1282
作者:  Li, S. -Q.;  Feng, L.;  Jiang, W. -D.;  Liu, Y.;  Wu, P.
收藏  |  浏览/下载:223/0  |  提交时间:2019/09/05
Optimal dietary alpha-linolenic acid/linoleic acid ratio improved digestive and absorptive capacities and target of rapamycin gene expression of juvenile grass carp (Ctenopharyngodon idellus) 期刊论文
AQUACULTURE NUTRITION, 2016, 卷号: 22, 期号: 6, 页码: 1251-1266
作者:  Zeng, Y. -Y.;  Jiang, W. -D.;  Liu, Y.;  Wu, P.;  Zhao, J.
收藏  |  浏览/下载:17/0  |  提交时间:2019/09/05
Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells 期刊论文
Cellular Signalling, 2016, 卷号: 28, 期号: 8, 页码: 1099-1104
作者:  Wang, Jing;  Yang, Xin;  Zhang, Jingjing*
收藏  |  浏览/下载:28/0  |  提交时间:2019/12/03
4E-BP1  4E binding protein  AMPK  AMP-activated protein kinase  ATF6  activating transcription factor 6  ATP  adenosine triphosphate  DEPTOR  DEP domain containing mTOR-interacting protein  CI  complexes I  CII  complex II  CIII  complex III  CIV  complex IV  CV  complex V  eIF2α  Eukaryotic Initiation Factor 2α  ER  Endoplasmic Reticulum  ERAD  ER-associated degradation  ERO1α  ER oxidoreductase 1 α  FoxO1  Forkhead box O1  GβL  G Protein β Subunit Like Protein  GRP78  78 kDa glucose-regulated protein precursor  GSIS  glucose-stimulated insulin secretion  IRE1  Inositol-requiring enzyme 1  IRS1  Insulin receptor substrate 1  IRS2  Insulin receptor substrate 2  mLST8  mammalian lethal with sec-13 protein 8  mSin1  the mammalian stress-activated MAP kinase-interaction protein 1  mtDNA  mitochondrial deoxyribonucleic acid  mTOR  mammalian TOR  mTORC1  mTOR complex 1  mTORC2  mTOR complex 2  NADPH oxidase  Nicotinamide adenine dinucleotide phosphate-oxidase  NOS  nitric oxide synthase  O2–·  superoxide anion  H2O2  hydrogen peroxide  OH·  hydroxyl radical  3O2  triplet-state molecular oxygen  OXPHOS  oxidative phosphorylation  CAT  catalase  GPx  glutathioneperoxidase  PERK  Protein kinase R-like endoplasmic reticulum kinase  PDI  ER protein disulfide isomerases  PI3K  the phosphoinositide3-kinase  PRAS40  40-kDa proline-rich Akt substrate  PRAS40  the 40-kDa proline-rich Akt substrate  PROTOR  the protein observed with RICTOR  RAPTOR  regulatory-associated protein of mTOR  RICTOR  The rapamycin-insensitive companion of mTOR  REDD1  DNA damage response 1  RNS  reactive nitrogen species  ROS  reactive oxygen species  RNS  reactive nitrogen species  S6K  S6 kinase  SOD  superoxidedismutase  T1DM  Type 1 diabetes mellitus  T2DM  Type 2 diabetes mellitus  TOR  the target of rapamycin  TSC2  Tuberous sclerosis 2  UPR  unfolded protein response  Mitochondrial oxidative stress  ER stress  mTOR  Pancreatic β cells  


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