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期刊论文 [9]
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学科主题:Biochemistry & Molecular Biology
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Ligand Efficiency Outperforms pIC(50) on Both 2D MLR and 3D CoMFA Models: A Case Study on AR Antagonists
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 86, 期号: 6, 页码: 1501-1517
作者:
Li, JZ
;
Bai, F
;
Liu, HX
;
Gramatica, P
;
Li, JZ (reprint author), Lanzhou Univ, Sch Pharm, 199 West Donggang Rd, Lanzhou 730000, Peoples R China.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/01/11
androgen receptor antagonist
comparative molecular field analysis
ligand efficiency
multiple linear regression
surface efficiency index
Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2013, 卷号: 1830, 期号: 10, 页码: 4681-4691
作者:
Lian, Wu
;
Wu, Mingyi
;
Huang, Ning
;
Gao, Na
;
Xiao, Chuang
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2013/11/12
Glycosaminoglycan
Anti-human immunodeficiency virus activity
Envelope glycoprotein 120
Cluster of Differentiation 4 induced epitope
Biolayer interferometry
Structure-activity relationship
Nonproton Ligand Sensing Domain Is Required for Paradoxical Stimulation of Acid-sensing Ion Channel 3 (ASIC3) Channels by Amiloride
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 卷号: 286, 期号: 49, 页码: 42635-42646
Li, Wei-Guang
;
Yu, Ye
;
Huang, Chen
;
Cao, Hui
;
Xu, Tian-Le(徐天乐)
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2012/07/13
GATED CATION CHANNEL
NA+ CHANNEL
INFLAMMATORY PAIN
MOLECULAR-CLONING
SENSORY NEURONS
CONTRIBUTES
CALCIUM
MODULATION
ISCHEMIA
LINKER
Structural and functional insights into polymorphic enzymes of cytochrome P450 2C8
期刊论文
AMINO ACIDS, 2011, 卷号: 40, 期号: 4, 页码: 1195-1204
作者:
Jiang, HL
;
Zhong, FF
;
Sun, L
;
Feng, WY
;
Huang, ZX
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2016/06/29
Structure-function relationship
Polymorphism
CYP2C8
Drug metabolism
Individualized medication
Rational design and synthesis of highly potent anti-acetylcholinesterase activity huperzine A derivatives
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 卷号: 17, 期号: 19, 页码: 6937-6941
作者:
Yan, Jian
;
Sun, Lirong
;
Wu, Guisheng
;
Yi, Ping
;
Yang, Fumei
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  |  
浏览/下载:14/0
  |  
提交时间:2012/03/21
Alzheimer's Disease
Hupzine a
Ache
Docking Study
Isolation and Difference in Anti-Staphylococcus aureus Bioactivity of Curvularin Derivates from Fungus Eupenicillium sp.
期刊论文
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2009, 卷号: 159, 期号: 1, 页码: 284-293
作者:
Li, X
;
Xie, LW
;
Ouyang, YC
;
Zou, K
;
Wang, GH
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  |  
浏览/下载:21/0
  |  
提交时间:2011/07/03
Curvularin
Alpha Beta-dehydrocurvularin
Anti-staphylococcus Aureus
Bioassay-guided Isolation
Synthesis, cytotoxic activity, and SAR analysis of the derivatives of taxchinin A and brevifoliol
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 卷号: 16, 期号: 9, 页码: 4860-4871
作者:
Zhao, Yu
;
Guo, Na
;
Lou, Li-Guang
;
Cong, Yu-Wen
;
Peng, Li-Yan
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2011/11/24
Derivatives Of Taxchinin a And Brevifoliol
Synthesis
Cytotoxicity
Sar
Preparation and in vitro antioxidant activity of kappa-carrageenan oligosaccharides and their oversulfated, acetylated, and phosphorylated derivatives
期刊论文
CARBOHYDRATE RESEARCH, 2005, 卷号: 340, 期号: 4, 页码: 685-692
作者:
Yuan, HM
;
Zhang, WW
;
Li, XG
;
Lu, XX
;
Li, N
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2010/12/22
Carrageenan Oligosaccharide
Oversulfated
Acetylated
Phosphorylated
Antioxidant Activity
In Vitro
Discrimination of tRNA(Leu) isoacceptors by the mutants of Escherichia coli Leucyl-tRNA synthetase in editing
期刊论文
BIOCHEMISTRY, 2002, 卷号: 41, 期号: 34, 页码: 10623-10628
作者:
Du, X
;
Wang, ED
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  |  
浏览/下载:8/0
  |  
提交时间:2015/07/22
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