×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [402]
内容类型
期刊论文 [215]
项目 [187]
发表日期
2021 [54]
2020 [88]
2019 [81]
2018 [45]
2017 [48]
2016 [10]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共402条,第1-10条
帮助
限定条件
专题:上海药物研究所
第一署名单位
第一作者单位
通讯作者单位
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
发表日期升序
发表日期降序
提交时间升序
提交时间降序
题名升序
题名降序
作者升序
作者降序
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12050202]
项目
项目编号: XDA12050202, 资助机构: Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences, 2021-
-
收藏
  |  
浏览/下载:164/0
  |  
提交时间:2021/05/24
Accucopy: accurate and fast inference of allele-specific copy number alterations from low-coverage low-purity tumor sequencing data
期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22, 期号: 1, 页码: 18
作者:
Fan, Xinping
;
Luo, Guanghao
;
Huang, Yu S.
收藏
  |  
浏览/下载:214/0
  |  
提交时间:2021/05/24
Cancer genomics
Copy number alterations
Next-generation sequencing
Personalized Medicines-Molecular Signature-based Drug Discovery and Development, Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12020229]
项目
项目编号: XDA12020229, 资助机构: Personalized Medicines-Molecular Signature-based Drug Discovery and Development, Strategic Priority Research Program of the Chinese Academy of Sciences, 2021-
-
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2022/01/18
GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhang, Qing
;
Chen, Lin-hai
;
Yang, Hui
;
Fang, You-chen
;
Wang, Si-wei
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/01/18
GPR84
medium chain fatty acid receptor
GPCR
inflammatory bowel diseases
ulcerative colitis
NLRP3 inflammasome
macrophages
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:
He, Yu-Long
;
Chen, Meng-Ting
;
Wang, Ting
;
Zhang, Ming-Ming
;
Li, Ying-Xia
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2021/11/04
Type 2 diabetes mellitus
Dual FABP4/5 inhibitors
Anti-lipolytic and anti-inflammatory effects
Metabolic stability
Anti-diabetic activities
SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade
期刊论文
EMBO JOURNAL, 2021, 页码: 16
作者:
Wang, Xu
;
Ni, Jiahui
;
You, Yan
;
Feng, Guize
;
Zhang, Sulin
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/12/16
E-cadherin
IBD
intestinal barrier function
LPS release
SNX10
Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation
期刊论文
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:
Li, Heng
;
Zhang, Xianglei
;
Xiang, Caigui
;
Feng, Chunlan
;
Fan, Chen
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/11/04
PDE4
Arctigenin
Psoriasis
Inflammation
Oxidized Low-Density Lipoprotein Links Hypercholesterolemia and Bladder Cancer Aggressiveness by Promoting Cancer Stemness
期刊论文
CANCER RESEARCH, 2021, 卷号: 81, 期号: 22, 页码: 5720-5732
作者:
Yang, Lin
;
Sun, Jingya
;
Li, Meiqian
;
Long, Yiming
;
Zhang, Dianzheng
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/01/04
Drug target inference by mining transcriptional data using a novel graph convolutional network framework
期刊论文
PROTEIN & CELL, 2021, 页码: 21
作者:
Zhong, Feisheng
;
Wu, Xiaolong
;
Yang, Ruirui
;
Li, Xutong
;
Wang, Dingyan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/12/01
drug target inference
transcriptomics
deep learning
experimental verification
©版权所有 ©2017 CSpace - Powered by
CSpace