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浏览/检索结果:
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学科主题:Pharmacology & Pharmacy
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Rubinoboletus ballouii polysaccharides exhibited immunostimulatory activities through toll-like receptor-4 via NF-kappa B pathway
期刊论文
PHYTOTHERAPY RESEARCH, 2020
作者:
Li, Long-Fei
;
Yue, Grace G-L
;
Chan, Ben C-L
;
Zeng, Qiang
;
Han, Quan-Bin
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2021/01/05
A Ganoderma-Derived Compound Exerts Inhibitory Effect Through Formyl Peptide Receptor 2
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020
作者:
Wang, Huirong
;
Peng, Xingrong
;
Ge, Yunjun
;
Zhang, Shuo
;
Wang, Zhenyi
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  |  
浏览/下载:11/0
  |  
提交时间:2021/01/05
Bioassay-guided isolation of saikosaponins with agonistic activity on 5-hydroxytryptamine 2C receptor from Bupleurum chinense and their potential use for the treatment of obesity
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 6, 页码: 467-473
作者:
Sun Chang-Li
;
Geng Chang-An
;
Huang Xiao-Yan
;
Ma Yun-Bao
;
Zheng Xiao-Hong
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  |  
浏览/下载:35/0
  |  
提交时间:2017/10/23
Bupleurum Chinense
5-hydroxytryptamine 2c (5-ht2c) Receptor
Anti-obesity
Saikosaponins
Rational Selection of the 3D Structure of Biomacromolecules for Molecular Docking Studies on the Mechanism of Endocrine Disruptor Action
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 卷号: 29, 期号: 9, 页码: 1565-1570
作者:
Yang, Xianhai
;
Liu, Huihui
;
Liu, Jining
;
Li, Fei
;
Li, Xuehua
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  |  
浏览/下载:58/0
  |  
提交时间:2016/11/30
POLYBROMINATED DIPHENYL ETHERS
THYROID-HORMONE-BINDING
HUMAN SERUM-ALBUMIN
IN-VITRO
ESTROGEN-RECEPTOR
RISK-ASSESSMENT
RECOMBINANT TRANSTHYRETIN
SCIENTIFIC STATEMENT
EVOLUTIONARY CHANGES
CHEMICALS
Pharmacological characterization of EN-9, a novel chimeric peptide of endomorphin-2 and neuropeptide FF that produces potent antinociceptive activity and limited tolerance
期刊论文
NEUROPHARMACOLOGY, 2016, 卷号: 108, 页码: 364-372
作者:
Wang, ZL
;
Li, N
;
Wang, P
;
Tang, HH
;
Han, ZL
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/01/10
Chimeric peptide
Endomorphin-2
Neuropeptide FF
Opioid
Antinociception
Non-tolerance
Role of histamine H1-receptor on behavioral states and wake maintenance during deficiency of a brain activating system: A study using a knockout mouse model
期刊论文
NEUROPHARMACOLOGY, 2016, 卷号: 106, 页码: 20-34
作者:
Parmentier, R
;
Zhao, Y
;
Perier, M
;
Akaoka, H
;
Lintunen, M
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2017/01/10
Wakefulness
Arousal
Sleep
Cortical activation
Histamine
H1-receptor
Knockout mice
EEG
Behavior
Cholinergic transmission
Compensation
Coptisine from Coptis chinensis inhibits production of inflammatory mediators in lipopolysaccharide-stimulated RAW 264.7 murine macrophage cells
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2016, 卷号: 780, 页码: 106-114
作者:
Wu, JS
;
Zhang, H
;
Hu, BY
;
Yang, LJ
;
Wang, P
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  |  
浏览/下载:12/0
  |  
提交时间:2017/11/09
Coptisine
Coptis Chinensis
Inflammation
Nitric Oxide
Macrophage
Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 12, 页码: 5911-5916
Wang, Zhen
;
Bian, Huan
;
Bartual, Sergio G.
;
Du, Wenting
;
Luo, Jinfeng
;
Zhao, Hu
;
Zhang, Shasha
;
Mo, Cheng
;
Zhou, Yang
;
Xu, Yong
;
Tu, Zhengchao
;
Ren, Xiaomei
;
Lu, Xiaoyun
;
Brekken, Rolf A.
;
Yao, Libo
;
Bullock, Alex N.
;
Su, Jin
;
Ding, Ke
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2016/12/16
Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 12, 页码: 5911-5916
作者:
Yao, Libo
;
Ding, Ke
;
Su, Jin
;
Bullock, Alex N.
;
Brekken, Rolf A.
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2018/12/13
Ligand Efficiency Outperforms pIC(50) on Both 2D MLR and 3D CoMFA Models: A Case Study on AR Antagonists
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 86, 期号: 6, 页码: 1501-1517
作者:
Li, JZ
;
Bai, F
;
Liu, HX
;
Gramatica, P
;
Li, JZ (reprint author), Lanzhou Univ, Sch Pharm, 199 West Donggang Rd, Lanzhou 730000, Peoples R China.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/01/11
androgen receptor antagonist
comparative molecular field analysis
ligand efficiency
multiple linear regression
surface efficiency index
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