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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang
收藏  |  浏览/下载：60/0  |  提交时间：2022/01/18
Transformer-Based Generative Model Accelerating the Development of Novel BRAF Inhibitors 期刊论文
ACS OMEGA, 2021, 卷号: 6, 期号: 49, 页码: 33864-33873
作者:  Yang, Lijuan;  Yang, Guanghui;  Bing, Zhitong;  Tian, Yuan;  Niu, Yuzhen
收藏  |  浏览/下载：16/0  |  提交时间：2022/04/11
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:  He, Yu-Long;  Chen, Meng-Ting;  Wang, Ting;  Zhang, Ming-Ming;  Li, Ying-Xia
收藏  |  浏览/下载：62/0  |  提交时间：2021/11/04
SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy 期刊论文
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 339, 页码: 297-306
作者:  Huang, Ying;  Wang, Lei;  Cheng, Zhiyang;  Yang, Biyu;  Yu, Jiahui
收藏  |  浏览/下载：21/0  |  提交时间：2021/12/01
The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206
作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen
收藏  |  浏览/下载：28/0  |  提交时间：2021/12/16
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/01
Synthesis of the analogs of plocabulin and their preliminary structure-activity relationship study 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 51, 页码: 5
作者:  Wang, Leiming;  Li, Xin;  Cui, Hong;  Lei, Xinsheng;  Liu, Hongchun
收藏  |  浏览/下载：29/0  |  提交时间：2021/12/01
Structural characteristics of Heparan sulfate required for the binding with the virus processing Enzyme Furin 期刊论文
GLYCOCONJUGATE JOURNAL, 2021, 页码: 11
作者:  Zeng, Jiaxin;  Meng, Yuan;  Chen, Shi-Yi;  Zhao, Gaofeng;  Wang, Lianchun
收藏  |  浏览/下载：51/0  |  提交时间：2021/12/01
Drug target inference by mining transcriptional data using a novel graph convolutional network framework 期刊论文
PROTEIN & CELL, 2021, 页码: 21
作者:  Zhong, Feisheng;  Wu, Xiaolong;  Yang, Ruirui;  Li, Xutong;  Wang, Dingyan
收藏  |  浏览/下载：20/0  |  提交时间：2021/12/01
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:  Wang, Shuni;  Yang, Hong;  Su, Mingbo;  Lian, Fulin;  Cong, Zhanqing
收藏  |  浏览/下载：80/0  |  提交时间：2021/11/04

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