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科研机构
上海药物研究所 [84]
内容类型
期刊论文 [82]
会议论文 [1]
学位论文 [1]
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2021 [1]
2020 [7]
2019 [5]
2018 [6]
2017 [3]
2016 [4]
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Neuroscien... [2]
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Protective Effects of 28-O-Caffeoyl Betulin (B-CA) on the Cerebral Cortex of Ischemic Rats Revealed by a NMR-Based Metabolomics Analysis
期刊论文
NEUROCHEMICAL RESEARCH, 2021, 页码: 13
作者:
Liu, Xia
;
Ruan, Zhi
;
Shao, Xing-cheng
;
Feng, Hong-xuan
;
Wu, Lei
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/05/24
Cerebral ischemia–
reperfusion
28-O-caffeoyl betulin
Neuroprotection
Metabolomics
NMR
SR mu CT Reveals 3D Microstructural Alterations of the Vascular and Neuronal Network in a Rat Model of Chronic Compressive Thoracic Spinal Cord Injury
期刊论文
AGING AND DISEASE, 2020, 卷号: 11, 期号: 3, 页码: 603-617
作者:
Jiang, Liyuan
;
Cao, Yong
;
Liu, Zhen
;
Ni, Shuangfei
;
Liu, Jun
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2020/07/01
chronic spinal cord injury
neurovascular unit
spinal cord microvasculature
SR mu CT
3D
An optically active isochroman-2H-chromene conjugate potently suppresses neuronal oxidative injuries associated with the PI3K/Akt and MAPK signaling pathways
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Tao, Ling-xue
;
Ji, Sha-sha
;
Szaloki, Dora
;
Kovacs, Tibor
;
Mandi, Attila
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
neurodegeneration
oxidative stress
apoptosis
MAPK pathway
PI3K
Akt pathway
SH-SY5Y neuroblastoma cells
Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Li, Man
;
Li, Shi-chun
;
Dou, Bao-kai
;
Zou, Ying-xiang
;
Han, Hao-zhen
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
cycloastragenol
SIRT1
apoptosis
neuroinflammation
cerebral ischemia
Repurposing antimycotic ciclopirox olamine as a promising anti-ischemic stroke agent
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 3, 页码: 434-446
作者:
Feng, Hongxuan
;
Hu, Linghao
;
Zhu, Hongwen
;
Tao, Lingxue
;
Wu, Lei
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Blood-brain barrier
Brain ischemia
Cell cycle
Inflammation
Neuroprotection
Recent advances in dopaminergic strategies for the treatment of Parkinson's disease
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Mao, Qi
;
Qin, Wang-zhi
;
Zhang, Ao
;
Ye, Na
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Parkinson's disease
dopamine
D-1 receptor
D-2 receptor
allosteric modulator
neuroprotection
multitarget
drug discovery and development
neurodegenerative diseases
Development of Novel N-hydroxypyridone Derivatives as Potential Anti-Ischemic Stroke Agents
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 3, 页码: 1051-1067
作者:
Hu, Linghao
;
Feng, Hongxuan
;
Zhang, Hongguang
;
Yu, Songda
;
Zhao, Qinyuan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
recentadvancesindopaminergicstrategiesforthetreatmentofparkinsonsdisease
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 4, 页码: 471
作者:
Mao Qi
;
Qin Wangzhi
;
Zhang Ao
;
Ye Na
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Parkinson’s disease
dopamine
D_1 receptor
D_2 receptor
allosteric modulator
neuroprotection
multitarget
drug discovery and development
neurodegenerative diseases
Caffeic acid reduces A53T alpha-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease
期刊论文
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 150, 页码: 14
作者:
Zhang, Yu
;
Wu, Qimei
;
Zhang, Lei
;
Wang, Qing
;
Yang, Zexian
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Caffeic acid
A53T
Parkinson's disease
Autophagy
JNK
Donepezil, a drug for Alzheimer's disease, promotes oligodendrocyte generation and remyelination
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 11, 页码: 1386-1393
作者:
Cui, Xue
;
Guo, Yu-e
;
Fang, Jia-hui
;
Shi, Chang-jie
;
Suo, Na
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2020/07/01
donepezil
aricept
oligodendrocyte
oligodendrocyte progenitor cell
differentiation
myelin sheaths
remyelination
CNS demyelinating disorders
multiple sclerosis
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