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科研机构
合肥物质科学研究院 [7]
上海药物研究所 [2]
自动化研究所 [1]
内容类型
期刊论文 [10]
发表日期
2021 [10]
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Genomic alterations in biliary tract cancer predict prognosis and immunotherapy outcomes
期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 卷号: 9
作者:
Chen, Xiaofeng
;
Wang, Deqiang
;
Liu, Jing
;
Qiu, Jingrong
;
Zhou, Jun
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/01/10
immunotherapy
tumor microenvironment
biomarkers
tumor
genetic markers
A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies
期刊论文
MOLECULAR CELL, 2021, 卷号: 81, 期号: 19, 页码: 4076-+
作者:
Liu, Zhiwei
;
Liu, Yingluo
;
Qian, Lili
;
Jiang, Shangwen
;
Gai, Xiameng
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/12/01
Pulmonary enteric adenocarcinoma
期刊论文
TRANSLATIONAL ONCOLOGY, 2021, 卷号: 14
作者:
Gong, Jiali
;
Fan, Ying
;
Lu, Hongyang
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/11/01
PEAC
Immunohistochemistry
Mutation analysis
Diagnosis
Prognosis
Clinical Relevance of PD-L1 Expression and CD8+T Cells' Infiltration in Patients With Lung Invasive Mucinous Adenocarcinoma
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:
Xu, Xiaoling
;
Li, Na
;
Wang, Ding
;
Chen, Wei
;
Fan, Yun
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/08/31
invasive mucinous adenocarcinoma
lung cancer
PD-L1 expression
CD8+T cells
tumor microenvironment
genetic characteristics
treatment
The genomic landscape of young and old lung cancer patients highlights age-dependent mutation frequencies and clinical actionability in young patients
期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2021
作者:
Cai, Lei
;
Chen, Yong
;
Tong, Xiaoling
;
Wu, Xue
;
Bao, Hua
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  |  
浏览/下载:60/0
  |  
提交时间:2021/06/15
EGFR
ERBB2
gene fusions
tyrosine kinase inhibitors
young lung cancer patients
KRAS-Mutant Non-Small Cell Lung Cancer: An Emerging Promisingly Treatable Subgroup
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:
Xie, Mingying
;
Xu, Xiaoling
;
Fan, Yun
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  |  
浏览/下载:45/0
  |  
提交时间:2021/06/15
KRAS-mutant
NSCLC
targeted therapy
immunotherapy
AMG510
MRTX849
ImmunoAIzer: A Deep Learning-Based Computational Framework to Characterize Cell Distribution and Gene Mutation in Tumor Microenvironment
期刊论文
CANCERS, 2021, 卷号: 13, 期号: 7, 页码: 21
作者:
Bian, Chang
;
Wang, Yu
;
Lu, Zhihao
;
An, Yu
;
Wang, Hanfan
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/05/17
deep learning
cell distribution
biomarker
tumor gene mutation
tumor microenvironment (TME)
semi-supervised learning
hematoxylin and eosin (H&
E)
Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRAS(G12C) inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 213, 页码: 17
作者:
Xiao, Xuanzheng
;
Lai, Mengzhen
;
Song, Zilan
;
Geng, Meiyu
;
Ding, Jian
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  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
KRAS
Covalent inhibitor
Pyridopyrimidinone
Antiproliferative effect
Scaffold hopping
Genomic Profiling and Prognostic Value Analysis of Genetic Alterations in Chinese Resected Lung Cancer With Invasive Mucinous Adenocarcinoma
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 10
作者:
Cai, Lei
;
Wang, Jiangfeng
;
Yan, Junrong
;
Zeng, Jian
;
Zhu, Liang
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/03/15
invasive mucinous adenocarcinoma
surgical resection
next generation sequencing
genomic profiling
prognostic biomarker
Genomic Profiling and Prognostic Value Analysis of Genetic Alterations in Chinese Resected Lung Cancer With Invasive Mucinous Adenocarcinoma
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 10
作者:
Cai, Lei
;
Wang, Jiangfeng
;
Yan, Junrong
;
Zeng, Jian
;
Zhu, Liang
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/03/15
invasive mucinous adenocarcinoma
surgical resection
next generation sequencing
genomic profiling
prognostic biomarker
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