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Positive Allosteric Modulation of AMPAR by PF-4778574 Produced Rapid Onset Antidepressant Actions in Mice 期刊论文
Cerebral cortex (New York, N.Y. : 1991), 2018
作者:  Shen, Mengxin;  Lv, Dan;  Li, Shuting;  Zhang, Yanhua;  Wang, Zhen
收藏  |  浏览/下载:104/0  |  提交时间:2019/01/08
Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma 期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 671-689
作者:  Wang, Qi;  Dai, Yang;  Ji, Yinchun;  Shi, Huanyu;  Guo, Zuhao
收藏  |  浏览/下载:85/0  |  提交时间:2019/01/08
Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds 期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1902-1912
作者:  Gong, Grace Qun;  Wang, Ke;  Dai, Xin-Chuan;  Zhou, Yan;  Basnet, Rajesh
收藏  |  浏览/下载:98/0  |  提交时间:2019/01/08
Remodeling Tumor-Associated Macrophages and Neovascularization Overcomes EGFR(T790M)-Associated Drug Resistance by PD-L1 Nanobody-Mediated Codelivery 期刊论文
SMALL, 2018, 卷号: 14, 期号: 47
作者:  Yin, Weimin;  Yu, Xiaolu;  Kang, Xuejia;  Zhao, Yuge;  Zhao, Pengfei
收藏  |  浏览/下载:100/0  |  提交时间:2019/01/08
Molecular modelling studies on cinnoline-based BTK inhibitors using docking and structure-based 3D-QSAR 期刊论文
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2018, 卷号: 29, 期号: 11, 页码: 847-873
作者:  Li, R.;  Du, Y.;  Shen, J.
收藏  |  浏览/下载:36/0  |  提交时间:2019/01/08
High-throughput screening campaigns against a PI3K alpha isoform bearing the H1047R mutation identified potential inhibitors with novel scaffolds 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1816-1822
作者:  Wang, Jia;  Gong, Grace Qun;  Zhou, Yan;  Lee, Woo-Jeong;  Buchanan, Christina Maree
收藏  |  浏览/下载:84/0  |  提交时间:2019/01/08
Design, Synthesis, and Biological Evaluation of Thieno[3,2-d]pyrimidine Derivatives as Potential Simplified Phosphatidylinositol 3-Kinase alpha (PI3Kα) inhibitors 期刊论文
Chemical biology & drug design, 2018
作者:  Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Song, Kun;  Ruan, Cong
收藏  |  浏览/下载:36/0  |  提交时间:2019/01/08
Discovery of Potent Irreversible Pan-Fibroblast Growth Factor Receptor (FGFR) Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 20, 页码: 9085-9104
作者:  Wang, Yuming;  Li, Lijun;  Fan, Jun;  Dai, Yang;  Jiang, Alan
收藏  |  浏览/下载:29/0  |  提交时间:2019/01/08
Pyrazolo[4,3-b]pyrimido[4,5-e][1,4]diazepine derivatives as new multi-targeted inhibitors of Aurora A/B and KDR 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 428-441
作者:  Zhang, Qiumeng;  Shen, Qianqian;  Gao, Lixin;  Tong, Linjiang;  Li, Jia
收藏  |  浏览/下载:34/0  |  提交时间:2019/01/08
Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia
收藏  |  浏览/下载:84/0  |  提交时间:2019/01/08


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