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科研机构
上海药物研究所 [17]
内容类型
期刊论文 [17]
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2022 [1]
2021 [1]
2020 [5]
2019 [1]
2018 [1]
2016 [3]
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Spatial lipidomics of eight edible nuts by desorption electrospray ionization with ion mobility mass spectrometry imaging
期刊论文
FOOD CHEMISTRY, 2022, 卷号: 371, 页码: 11
作者:
Hou, Jinjun
;
Zhang, Zijia
;
Zhang, Linlin
;
Wu, Wenyong
;
Huang, Yong
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/12/16
Desorption electrospray ionization (DESI)
Mass spectrometry imaging (MSI)
Ion mobility
Collision cross section (CCS)
Nuts
Phospholipids
Fatty acid derivatives
Distribution profiles
A novel low systemic diacylglycerol acyltransferase 1 inhibitor, Yhhu2407, improves lipid metabolism
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 卷号: 158, 页码: 9
作者:
Huang, Jun-Shang
;
Guo, Bin-Bin
;
Lin, Fei-Fei
;
Zeng, Li-Min
;
Wang, Ting
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/05/24
DGAT1
Inhibitor
Pharmacokinetics
Dyslipidemia
Lipid metabolism
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 卷号: 404, 页码: 14
作者:
Wang, Ying
;
Zhu, Yao
;
Niu, Junxing
;
Deng, Qiangqiang
;
Guo, Shimeng
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  |  
浏览/下载:59/0
  |  
提交时间:2020/12/21
Bile acid analog
NASH
TGR5
Cd36
AMPK alpha
A rapid and convenient derivatization method for quantitation of short-chain fatty acids in human feces by ultra-performance liquid chromatography/tandem mass spectrometry
期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2020, 卷号: 34, 期号: 9, 页码: 11
作者:
Fu, Huan
;
Zhang, Qing-li
;
Huang, Xiao-wu
;
Ma, Zheng-hua
;
Zheng, Xiao-li
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  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Dihydro-stilbene gigantol relieves CCl4-induced hepatic oxidative stress and inflammation in mice via inhibiting C5b-9 formation in the liver
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 14
作者:
Xue, Ya-ru
;
Yao, Sheng
;
Liu, Qian
;
Peng, Zhao-liang
;
Deng, Qiang-qiang
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
gigantol
Chinese traditional medicine
liver injury
oxidative stress
inflammation
label-free proteomic
complement and coagulation cascades
terminal complement complex
Quantification of microbiota-related phenols and aromatic acids in mouse feces of a diabetic nephropathy model by simultaneous BDAPE derivatization using ultra-performance liquid chromatography-tandem mass spectrometry
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 卷号: 412, 期号: 13, 页码: 3241-3252
作者:
Zheng, Xiaoli
;
Duan, Haonan
;
Lin, Feifei
;
Li, Xiaomei
;
Shen, Jianhua
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  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Phenols
Aromatic acid
Microbiota
Uremic toxin
Simultaneous derivatization
2-Bromo-1-[4-(dimethylamino)phenyl] ethyl ketone
Identification and structural insight of an effective PPAR gamma modulator with improved therapeutic index for anti-diabetic drug discovery
期刊论文
CHEMICAL SCIENCE, 2020, 卷号: 11, 期号: 8, 页码: 2260-2268
作者:
Jiang, Haowen
;
Zhou, X. Edward
;
Shi, Jingjing
;
Zhou, Zhi
;
Zhao, Guanguan
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  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4 (vol 154, pg 44, 2018)
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 170, 页码: 235-236
作者:
Gao, Ding-Ding
;
Dou, Hui-Xia
;
Su, Hai-Xia
;
Zhang, Ming-Ming
;
Wang, Ting
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
From hit to lead: Structure-based discovery of naphthalene-1 sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 154, 页码: 44-59
作者:
Gao, Ding-Ding
;
Dou, Hui-Xia
;
Su, Hai-Xia
;
Zhang, Ming-Ming
;
Wang, Ting
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
FABP4 inhibitors
FABP3 sparing
Structure-based design strategy
X-ray crystallography
Analysis of diacylglycerols by ultra performance liquid chromatography-quadrupole time-of-flight mass spectrometry: Double bond location and isomers separation
期刊论文
ANALYTICA CHIMICA ACTA, 2016, 卷号: 925, 页码: 23-33
作者:
Deng, Pan
;
Zhong, Dafang
;
Wang, Xi
;
Dai, Yulu
;
Zhou, Lei
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Diacylglycerol
Liquid chromatography
Mass spectrometry
Dimethyl disulfide derivative
Double bond location
Collision cross-section
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