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Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing
收藏  |  浏览/下载:22/0  |  提交时间:2022/01/18
A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11
作者:  Cheng, Zhiyang;  Huang, Ying;  Shen, Qianqian;  Zhao, Yangrong;  Wang, Lei
收藏  |  浏览/下载:83/0  |  提交时间:2021/11/04
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Dong, Ying;  Tang, Bi-xi;  Wang, Qi;  Zhou, Li-wei;  Li, Cong
收藏  |  浏览/下载:70/0  |  提交时间:2022/01/04
Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation 期刊论文
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:  Li, Heng;  Zhang, Xianglei;  Xiang, Caigui;  Feng, Chunlan;  Fan, Chen
收藏  |  浏览/下载:84/0  |  提交时间:2021/11/04
Structures of full-length glycoprotein hormone receptor signalling complexes 期刊论文
NATURE, 2021, 页码: 24
作者:  Duan, Jia;  Xu, Peiyu;  Cheng, Xi;  Mao, Chunyou;  Croll, Tristan
收藏  |  浏览/下载:50/0  |  提交时间:2021/11/04
Exploring the Regulatory Function of the N-terminal Domain of SARS-CoV-2 Spike Protein through Molecular Dynamics Simulation 期刊论文
ADVANCED THEORY AND SIMULATIONS, 2021, 页码: 13
作者:  Li, Yao;  Wang, Tong;  Zhang, Juanrong;  Shao, Bin;  Gong, Haipeng
收藏  |  浏览/下载:50/0  |  提交时间:2021/11/04
ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 9
作者:  Chen, Yuning;  Zhang, Ya-Nan;  Yan, Renhong;  Wang, Guifeng;  Zhang, Yuanyuan
收藏  |  浏览/下载:64/0  |  提交时间:2021/11/04
Discovery of Cyclic Peptidomimetic Ligands Targeting the Extracellular Domain of EGFR 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 11219-11228
作者:  Zheng, Mengmeng;  Li, Chunpu;  Zhou, Mi;  Jia, Ru;  Cai, Gang
收藏  |  浏览/下载:60/0  |  提交时间:2021/11/04
Metabolically controlled histone H4K5 acylation/acetylation ratio drives BRD4 genomic distribution 期刊论文
CELL REPORTS, 2021, 卷号: 36, 期号: 4, 页码: 22
作者:  Gao, Mengqing;  Wang, Jin;  Rousseaux, Sophie;  Tan, Minjia;  Pan, Lulu
收藏  |  浏览/下载:63/0  |  提交时间:2021/11/04
Identification of novel anti-inflammatory Nur77 modulators by virtual screening 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 7
作者:  Ding, Xiaoyu;  Zhao, Zijie;  Wu, Yue;  Zhang, Hao;  Chen, Kaixian
收藏  |  浏览/下载:43/0  |  提交时间:2021/08/17


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