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科研机构
上海药物研究所 [22]
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期刊论文 [22]
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2021 [1]
2020 [1]
2018 [2]
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Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice
期刊论文
TOXICOLOGY LETTERS, 2020, 卷号: 333, 页码: 290-302
作者:
Zhao, Jie
;
Xie, Cen
;
Wang, Kanglong
;
Takahashi, Shogo
;
Krausz, Kristopher W.
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/12/21
Triptolide
Transcriptomics
Metabolomics
Apoptosis
Acylcarnitine
Astragaloside IV Attenuates Acetaminophen-Induced Liver Injuries in Mice by Activating the Nrf2 Signaling Pathway
期刊论文
Molecules (Basel, Switzerland), 2018, 卷号: 23, 期号: 8
作者:
Li, Lei
;
Huang, Wenxiang
;
Wang, Shoukai
;
Sun, Kecheng
;
Zhang, Wenxue
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
Baicalein and baicalin alleviate acetaminophen-induced liver injury by activating Nrf2 antioxidative pathway: The involvement of ERK1/2 and PKC
期刊论文
Biochemical pharmacology, 2018, 卷号: 150, 页码: 9-23
作者:
Shi, Liang
;
Hao, Zhanxia
;
Zhang, Shaobo
;
Wei, Mengjuan
;
Lu, Bin
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Long-term acetaminophen treatment induced liver fibrosis in mice and the involvement of Egr-1
期刊论文
Toxicology, 2017, 卷号: 382, 页码: 47-58
作者:
Bai, Qingyun
;
Yan, Hongyu
;
Sheng, Yuchen
;
Jin, Yao
;
Shi, Liang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Alleviative effects from boswellic acid on acetaminophen-induced hepatic injury
期刊论文
BioMedicine, 2016, 卷号: 6, 期号: 2, 页码: 9
作者:
Chen, Lung-Che
;
Hu, Li-Hong
;
Yin, Mei-Chin
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Microstructural investigation using synchrotron radiation X-ray microtomography reveals taste-masking mechanism of acetaminophen microspheres
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2016, 卷号: 499, 期号: 1-2, 页码: 47-57
作者:
Guo, Zhen
;
Yin, Xianzhen
;
Liu, Congbiao
;
Wu, Li
;
Zhu, Weifeng
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Taste masking
Lipid microspheres
Dissolution test
Microstructure
Synchrotron radiation X-ray computed microtomography
Three dimensional reconstruction
Simultaneous high-throughput determination of interaction kinetics for drugs and cyclodextrins by high performance affinity chromatography with mass spectrometry detection
期刊论文
ANALYTICA CHIMICA ACTA, 2016, 卷号: 909, 页码: 75-83
作者:
Wang, Caifen
;
Wang, Xiaobo
;
Xu, Xiaonan
;
Liu, Botao
;
Xu, Xu
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Cyclodextrin supramolecular systems
High performance affinity chromatography with mass spectrometry detection
High-throughput quantifying
Interactions kinetics
Caffeic acid prevents acetaminophen-induced liver injury by activating the Keap1-Nrf2 antioxidative defense system
期刊论文
Free radical biology & medicine, 2016, 卷号: 91, 页码: 236-46
作者:
Pang, Chun
;
Zheng, Zhiyong
;
Shi, Liang
;
Sheng, Yuchen
;
Wei, Hai
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Chemical and Enzymatic Transformations of Nimesulide to GSH Conjugates through Reductive and Oxidative Mechanisms
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2015, 卷号: 28, 期号: 12, 页码: 2267-2277
作者:
Zhou, Lei
;
Pang, Xiaoyan
;
Xie, Cen
;
Zhong, Dafang
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
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