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浏览/检索结果: 共27条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6 作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing 收藏  |  浏览/下载：23/0  |  提交时间：2022/01/18 Binding studies  Drug discovery  Necroptosis  RIPK1 inhibitors  Sepsis   Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation 期刊论文 JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251 作者:  Li, Heng;  Zhang, Xianglei;  Xiang, Caigui;  Feng, Chunlan;  Fan, Chen 收藏  |  浏览/下载：86/0  |  提交时间：2021/11/04 PDE4  Arctigenin  Psoriasis  Inflammation   Untargeted metabolomics coupled with chemometric analysis deducing robust markers for discrimination of processing procedures: Wine-processed Angelica sinensis as a case study 期刊论文 JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 19 作者:  Yin, Haoran;  Ni, Hui;  Zhang, Linlin;  Wu, Wenyong;  Wu, Xingdong 收藏  |  浏览/下载：22/0  |  提交时间：2021/12/01 Angelica sinensis  processing procedures  traditional Chinese medicine  untargeted metabolomics  wine-processing markers   Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function 期刊论文 CELL RESEARCH, 2021, 页码: 18 作者:  Xu, Xiang;  Ding, Guangjin;  Liu, Caizhi;  Ding, Yuhan;  Chen, Xiaoxin 收藏  |  浏览/下载：63/0  |  提交时间：2021/11/04 Novel selective kappa agonists SLL-039 and SLL-1206 produce potent antinociception with fewer sedation and aversion 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Wei, Yuan-yuan;  Ma, Yan;  Yao, Song-yu;  Kong, Ling-hui;  Liu, Xiao 收藏  |  浏览/下载：37/0  |  提交时间：2021/11/04 kappa-opioid receptor agonist  4,5-expoxymorphinan  antinociception  conditioned place aversion  sedation  U50,488H  morphine  Nor-BNI  beta-FNA   Polyprenylated acylphloroglucinol meroterpenoids with PTP1B inhibition from Hypericum forrestii 期刊论文 FITOTERAPIA, 2021, 卷号: 153, 页码: 5 作者:  Zong, Jian-Fa;  Zhang, Meng-Meng;  Zhou, Yu-Bo;  Li, Jia;  Hou, Ai-Jun 收藏  |  浏览/下载：64/0  |  提交时间：2021/11/04 Hypericum forrestii (Chittenden) N Robson  Clusiaceae  Acylphloroglucinol meroterpenoid  Hyperiforins A-C  Protein tyrosine phosphatase 1B   Restoring perturbed oxylipins with Danqi Tongmai Tablet attenuates acute myocardial infarction 期刊论文 PHYTOMEDICINE, 2021, 卷号: 90, 页码: 12 作者:  Zhi, Haijuan;  Zhang, Zijia;  Deng, Yanping;  Yan, Bingpeng;  Li, Zhenwei 收藏  |  浏览/下载：47/0  |  提交时间：2021/11/04 Acute myocardial infarction  Danqi Tongmai tablet  In vivo metabolite  Oxylipin  Arachidonic acid metabolome  Homeostasis   Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers 期刊论文 CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273 作者:  Chen, Zhen-dong;  Chen, Qian;  Zhu, Yun-ting;  Zhang, Yi-fan;  Zhan, Yan 收藏  |  浏览/下载：34/0  |  提交时间：2022/01/04 henagliflozin  food effects  mass balance  pharmacokinetics  SGLT-2 inhibitor   Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199 作者:  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Liang, Xiaoying;  Lan, Yuan 收藏  |  浏览/下载：40/0  |  提交时间：2021/11/04 Enzyme-Activated Prodrug-Based Smart Liposomes Specifically Enhance Tumor Hemoperfusion with Efficient Drug Delivery to Pancreatic Cancer Cells and Stellate Cells 期刊论文 ADVANCED FUNCTIONAL MATERIALS, 2021, 页码: 14 作者:  Duan, Nianxiu;  Li, Junjun;  Song, Sha;  Wang, Feng;  Yang, Yiwei 收藏  |  浏览/下载：25/0  |  提交时间：2021/11/04 drug delivery  pancreatic cancer  prodrugs  smart liposomes  tumor-specific vascular promotion