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新疆理化技术研究所 [10]
厦门大学 [3]
北京大学 [3]
大连化学物理研究所 [3]
高能物理研究所 [2]
中国科学院大学 [2]
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期刊论文 [31]
学位论文 [1]
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TransformerCPI: improving compound-protein interaction prediction by sequence-based deep learning with self-attention mechanism and label reversal experiments
期刊论文
BIOINFORMATICS, 2020, 卷号: 36, 期号: 16, 页码: 4406-4414
作者:
Chen, Lifan
;
Tan, Xiaoqin
;
Wang, Dingyan
;
Zhong, Feisheng
;
Liu, Xiaohong
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/05/24
Prediction of Drug-Target Interactions From Multi-Molecular Network Based on Deep Walk Embedding Model
期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, 卷号: 8, 期号: 6, 页码: 1-9
作者:
Chen, ZH (Chen, Zhan-Heng)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Guo, ZH (Guo, Zhen-Hao)[ 1,2 ]
;
Yi, HC (Yi, Hai-Cheng)[ 1,2 ]
;
Luo, GX (Luo, Gong-Xu)[ 1,2 ]
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/09/09
drug-target interactions
molecular association network
attribute feature
behavior feature
random forest
NLPEI: A Novel Self-Interacting Protein Prediction Model Based on Natural Language Processing and Evolutionary Information
期刊论文
EVOLUTIONARY BIOINFORMATICS, 2020, 卷号: 16, 期号: 12, 页码: 1-12
作者:
Jia, LN (Jia, Li-Na)[ 1 ]
;
Yan, X (Yan, Xin)[ 2,3 ]
;
You, ZH (You, Zhu-Hong)[ 4 ]
;
Zhou, X (Zhou, Xi)[ 4 ]
;
Li, LP (Li, Li-Ping)[ 4 ]
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/03/19
Self-interacting protein
natural language processing
evolutionary information
stacked auto-encoder
NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction
期刊论文
GENES & DEVELOPMENT, 2019, 卷号: 33, 期号: 9-10, 页码: 536-549
作者:
Wang, Jianshu
;
Chen, Jiyun
;
Wu, Guifen
;
Zhang, Hongling
;
Du, Xian
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2019/06/20
NRDE2
the nuclear exosome
MTR4 recruitment
mRNA export
An Improved Deep Forest Model for Predicting Self-Interacting Proteins From Protein Sequence Using Wavelet Transformation
期刊论文
FRONTIERS IN GENETICS, 2019, 卷号: 10, 期号: 3, 页码: 1-10
作者:
Chen, ZH (Chen, Zhan-Heng)[ 1,2 ]
;
Li, LP (Li, Li-Ping)[ 1 ]
;
He, Z (He, Zhou)[ 3 ]
;
Zhou, JR (Zhou, Ji-Ren)[ 1 ]
;
Li, YM (Li, Yangming)[ 4 ]
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/03/19
self-interacting proteins
disease
position-specific scoring matrix
deep learning
wavelet transform
Prediction of Self-Interacting Proteins from Protein Sequence Information Based on Random Projection Model and Fast Fourier Transform
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 卷号: 20, 期号: 4, 页码: 1-15
作者:
Chen, ZH (Chen, Zhan-Heng)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Li, LP (Li, Li-Ping)[ 1 ]
;
Wang, YB (Wang, Yan-Bin)[ 1 ]
;
Wong, L (Wong, Leon)[ 1,2 ]
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/05/16
self-interacting proteins
position-specific scoring matrix
fast Fourier transform
random projection
Global Vectors Representation of Protein Sequences and Its Application for Predicting Self-Interacting Proteins with Multi-Grained Cascade Forest Model
期刊论文
GENES, 2019, 卷号: 10, 期号: 11, 页码: 1-12
作者:
Chen, ZH (Chen, Zhan-Heng)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1,2 ]
;
Zhang, WB (Zhang, Wen-Bo)[ 1,2 ]
;
Wang, YB (Wang, Yan-Bin)[ 1 ]
;
Cheng, L (Cheng, Li)[ 1,2 ]
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/01/10
self-interacting proteins
de novo protein sequence
global vector representation
multi-grained cascade forest
Improving Prediction of Self-interacting Proteins Using Stacked Sparse Auto-Encoder with PSSM profiles
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018, 卷号: 14, 期号: 8, 页码: 983-991
作者:
Wang, YB (Wang, Yan-Bin)
;
You, ZH (You, Zhu-Hong)
;
Li, LP (Li, Li-Ping)
;
Huang, DS (Huang, De-Shuang)
;
Zhou, FF (Zhou, Feng-Feng)
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2018/07/16
Deep Learning
Zernike Moments
Probabilistic Classification Vector Machines
Prediction of protein self-interactions using stacked long short-term memory from protein sequences information
期刊论文
BMC SYSTEMS BIOLOGY, 2018, 卷号: 12, 期号: 增刊: 8, 页码: 1-9
作者:
Wang, YB (Wang, Yan-Bin)[ 1,2 ]
;
You, ZH (You, Zhu-Hong)[ 1 ]
;
Li, X (Li, Xiao)[ 1 ]
;
Jiang, TH (Jiang, Tong-Hai)[ 1 ]
;
Cheng, L (Cheng, Li)[ 1 ]
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/03/26
Self-interacting proteins
Stacked long short-term memory
Deep learning
Dropout
Structural and saxs analysis of tle5-tli5 complex reveals a novel inhibition mechanism of h2-t6ss in pseudomonas aeruginosa
期刊论文
Protein science, 2017, 卷号: 26, 期号: 10, 页码: 2083-2091
作者:
Yang, Xiao-Yun
;
Li, Zong-Qiang
;
Gao, Zeng-Qiang
;
Wang, Wen-Jia
;
Geng, Zhi
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/04/23
X-ray crystallography
Saxs
Immunity protein
Type vi secretion system
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