CORC

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CORC

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JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers 期刊论文
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:  Lu, Xuxiu;  Yu, Rilei;  Li, Zhen;  Yang, Mengke;  Dai, Jiajia
收藏  |  浏览/下载：2/0  |  提交时间：2024/04/07
Discovery of Pyrrolo[2,3-d]pyrimidine derivatives as potent and selective colony stimulating factor 1 receptor kinase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243
作者:  Liang, Xiaofei;  Wang, Chun;  Wang, Beilei;  Liu, Juan;  Qi, Shuang
收藏  |  浏览/下载：25/0  |  提交时间：2022/12/23
Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis 期刊论文
BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424
作者:  Wang, Jin;  Xie, Si-an;  Li, Ning;  Zhang, Tao;  Yao, Weijuan
收藏  |  浏览/下载：103/0  |  提交时间：2022/06/10
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Dong, Ying;  Tang, Bi-xi;  Wang, Qi;  Zhou, Li-wei;  Li, Cong
收藏  |  浏览/下载：70/0  |  提交时间：2022/01/04
Profiling Receptor Tyrosine Kinase Fusions in Chinese Breast Cancers 期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:  Tao, Zhonghua;  Liu, Jianxia;  Li, Ting;  Xu, Hong;  Chen, Kai
收藏  |  浏览/下载：30/0  |  提交时间：2022/01/10
Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl Inhibitor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 7, 页码: 3956-3975
作者:  Zhang, Hefeng;  Peng, Xia;  Dai, Yang;  Shao, Jingwei;  Ji, Yinchun
收藏  |  浏览/下载：16/0  |  提交时间：2021/06/11
Transcriptomic analysis of glioblastoma multiforme providing new insights into GPR17 signaling communication 期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020, 页码: 14
作者:  Mutharasu, Gnanavel;  Murugesan, Akshaya;  Konda Mani, Saravanan;  Yli-Harja, Olli;  Kandhavelu, Meenakshisundaram
收藏  |  浏览/下载：23/0  |  提交时间：2020/12/10
Repurposing of Kinase Inhibitors for Treatment of COVID-19 期刊论文
PHARMACEUTICAL RESEARCH, 2020, 卷号: 37
作者:  Weisberg, Ellen;  Parent, Alexander;  Yang, Priscilla L.;  Sattler, Martin;  Liu, Qingsong
收藏  |  浏览/下载：30/0  |  提交时间：2020/10/26
YES1amplification confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive cancer 期刊论文
BRITISH JOURNAL OF CANCER, 2020, 页码: 12
作者:  Wang, Lei;  Wang, Quanren;  Xu, Piaopiao;  Fu, Li;  Li, Yun
收藏  |  浏览/下载：15/0  |  提交时间：2020/12/24
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:  Lai, Meng-zhen;  Song, Pei-ran;  Dou, Dou;  Diao, Yan-yan;  Tong, Lin-jiang
收藏  |  浏览/下载：34/0  |  提交时间：2020/07/01

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