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期刊论文 [45]
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Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors
期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:
Xu, Jianghong
;
Hu, Yuanyuan
;
Liu, Xiaoqi
;
Gao, Anhui
;
Gao, Lixin
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/12/01
IDH1-R132H inhibitors
synthesis
biological activity
docking
3-(indol-3-yl)-4-(pyrazolo-[3
4-c]pyridazin-3-yl)-maleimides
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:
Liu, Xiaohua
;
Zhang, Yu
;
Li, Yalei
;
Wang, Juan
;
Ding, Huaqian
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/05/24
Medulloblastoma
Hedgehog signaling
pathway
Drug resistance
GLI
BRD4
Repurposing of Kinase Inhibitors for Treatment of COVID-19
期刊论文
PHARMACEUTICAL RESEARCH, 2020, 卷号: 37
作者:
Weisberg, Ellen
;
Parent, Alexander
;
Yang, Priscilla L.
;
Sattler, Martin
;
Liu, Qingsong
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/10/26
Coronavirus
SARS-CoV-2
SARS-CoV
MERS-CoV
kinase inhibitors
pharmacokinetics
antiviral therapy
COVID-19
Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer's disease
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 4, 页码: 646-666
作者:
Li, Xiaokang
;
Lu, Jian
;
Xu, Yixiang
;
Wang, Jiaying
;
Qiu, Xiaoxia
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  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
Alzheimer's disease
Autophagy
Nitazoxanide
beta-amyloid
Tau protein
Discovery of Novel PRMT5 Inhibitors by Virtual Screening and Biological Evaluations
期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2019, 卷号: 67, 期号: 4, 页码: 382-388
作者:
Tao, Hongrui
;
Yan, Xue
;
Zhu, Kongkai
;
Zhang, Hua
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
virtual screening
epigenetic inhibitor
antiproliferation
molecular docking
Recent progress and challenges in screening and characterization of UGT1A1 inhibitors
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 2, 页码: 258-278
作者:
Finel, Moshe
;
Lv, Xia
;
Xia, Yangliu
;
Wu, Jingjing
;
Ge, Guangbo
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  |  
浏览/下载:73/0
  |  
提交时间:2019/06/20
UGT1A1 inhibitors
Drug/herbdrug interactions
Probe substrates
High-throughput screening
Recent progress and challenges in screening and characterization of ugt1a1 inhibitors
期刊论文
Acta pharmaceutica sinica b, 2019, 卷号: 9, 期号: 2, 页码: 258-278
作者:
Lv, Xia
;
Xia, Yangliu
;
Finel, Moshe
;
Wu, Jingjing
;
Ge, Guangbo
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2019/05/08
Ugt1a1 inhibitors
Drug/herbdrug interactions
Probe substrates
High-throughput screening
Biogenic ‐‐Lipoic Acid Only Constructed Cross‐Linked Vesicles with Synergistic Anticancer Potency
期刊论文
Advanced Functional Materials, 2019, 卷号: Vol.29 No.3
作者:
Chunyan Liao
;
Xin Dai
;
Ying Chen
;
Jie Liu
;
Yongchao Yao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/02/25
drug
delivery
(R)‐(+)‐lipoic
acid
superamphiphile
synergistic
therapy
vesicles
recentprogressandchallengesinscreeningandcharacterizationofugt1a1inhibitors
期刊论文
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 2, 页码: 258
作者:
Lv Xia
;
Xia Yangliu
;
Finel Moshe
;
Wu Jingjing
;
Ge Guangbo
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/02
Improved method for synthesis of low molecular weight protamine-siRNA conjugate
期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 1, 页码: 116-126
作者:
Yu, Zhili
;
Ye, Junxiao
;
Pei, Xing
;
Sun, Lu
;
Liu, Ergang
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Cell penetrating peptide
siRNA
Conjugate
Conjugation yield
Biomimetic delivery
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