×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
复旦大学上海医学院 [18]
大连理工大学 [15]
北京大学 [10]
过程工程研究所 [4]
水生生物研究所 [3]
四川大学 [3]
更多...
内容类型
期刊论文 [60]
会议论文 [4]
学位论文 [2]
专利 [1]
发表日期
2019 [3]
2018 [2]
2017 [5]
2016 [1]
2015 [1]
2014 [4]
更多...
学科主题
Biochemist... [1]
Biochemist... [1]
生理心理学/生物心理... [1]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共67条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
A novel thrombin inhibitory peptide discovered from leech using affinity chromatography combined with ultra-high performance liquid chromatography-high resolution mass spectroscopy
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020, 卷号: 1151, 页码: 8
作者:
Huang, Qiuyang
;
Gao, Qian
;
Chai, Xiaoxin
;
Ren, Wei
;
Zhang, Guifeng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/23
Thrombin
Bioactive Compound Screening
Affinity Chromatography
Uplc-hr-ms
Leech
Thrombin Inhibitory Activity
Endothelial cell-specific anticoagulation reduces inflammation in a mouse model of acute lung injury
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 6
作者:
Lou, Jian
;
Hu, Yue
;
Wu, Min-dan
;
Che, Luan-qing
;
Wu, Yin-fang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
acute lung injury
lipopolysaccharide
endothelial cells
anticoagulants
human tissue factor pathway inhibitor (hTFPI)
hirudin
CCL2
inflammation
Chemical modification of recombinant hirudin with palmitic acid in mixed aqueous-organic solutions
期刊论文
PROCESS BIOCHEMISTRY, 2019, 卷号: 77, 页码: 85-92
作者:
Wang, Shu-Chang
;
Wang, Xu-Dong
;
Teng, Xin-Nan
;
Xiu, Zhi-Long
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/02
Recombinant hirudin
Chemical modification
Fatty acid-conjugation
Long-chain fatty acids
Palmitic acid
Mixed aqueous-organic solutions
Expression, Purification and Functional Evaluation of Neorudin-Human IgG-Fc Fusion Protein
期刊论文
Journal of Tianjin University Science and Technology, 2019, 卷号: Vol.52 No.2, 页码: 136-142
作者:
Wu, Z.
;
Wang, K.
;
Li, S.
;
Dong, X.
;
Dou, G.
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/11/21
Anticoagulant activity
Fc fusion protein
Half-life
Hirudin(HV)
Neorudin(EH)
Combined optimization of N-terminal site-specific PEGylation of recombinant hirudin using response surface methodology and kinetic analysis
期刊论文
ENGINEERING IN LIFE SCIENCES, 2018, 卷号: 18, 页码: 611-621
作者:
Wang, Xudong
;
Wang, Shuchang
;
Pan, Duotao
;
Qin, Kairong
;
Yuan, Hengli
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/02
Kinetic analysis
Optimization
PEGylation
Recombinant hirudin
Response surface methodology
Effects of Natural Hirudin and Low Molecular Weight Heparin in Preventing Deep Venous Thrombosis in Aged Patients with Intertrochanteric Fracture
期刊论文
Scientific Reports, 2018, 卷号: Vol.8
作者:
Zhang, ZD
;
Li, Z
;
Li, J
;
Liu, L
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/02/25
A novel hirudin derivative inhibiting thrombin without bleeding for subcutaneous injection
期刊论文
THROMBOSIS AND HAEMOSTASIS, 2017, 卷号: 117, 期号: 1
作者:
Huang, Yinong
;
Zhao, Bing
;
Zhang, Yanling
;
Yu, Jinchao
;
Li, Yaran
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Thrombin
r-RGD-hirudin
thrombosis
subcutaneous injection
direct thrombin inhibitor peptide (DTIP)
In situ PEGylation of recombinant hirudin on an anion exchange chromatography column
期刊论文
PROCESS BIOCHEMISTRY, 2017, 卷号: 55, 页码: 162-171
作者:
Wang, Xudong
;
Li, Xueqin
;
Zhao, Jun
;
Lv, Li
;
Qin, Kairong
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/02
Recombinant hirudin
PEGylation
Ion exchange chromatography
In situ PEGylation
Solid-phase PEGylation
On-column PEGylation
Effects of linear and branched polyethylene glycol on PEGylation of recombinant hirudin: Reaction kinetics and in vitro and in vivo bioactivities
期刊论文
PROCESS BIOCHEMISTRY, 2017, 卷号: 63, 页码: 154-162
作者:
Wang, Xudong
;
Lv, Li
;
Qin, Kairong
;
Yuan, Hengli
;
Zhang, Fengying
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/03
Recombinant hirudin
PEGylation
Branched mPEG
Reaction kinetics
In vitro anticoagulant activity
In vivo pharmacological efficacy
A novel natural hirudin facilitated anti-clotting polylactide membrane via hydrogen bonding interaction
期刊论文
JOURNAL OF MEMBRANE SCIENCE, 2017, 卷号: 523, 页码: 505-514
作者:
Liu, Fu
;
Li, Jinglong
;
Deng, Gang
;
Xiong, Zhu
;
He, Jidong
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2017/12/25
©版权所有 ©2017 CSpace - Powered by
CSpace