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北京大学 [8]
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期刊论文 [51]
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Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists
期刊论文
PHARMACEUTICALS, 2022, 卷号: 15
作者:
Sun, Lei
;
Zheng, Zhi-Ming
;
Shao, Chang-Sheng
;
Zhang, Zhi-Yong
;
Li, Ming-Wei
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/12/22
glucagon-like peptide-1
GLP-1 receptor agonist
functional protein design
molecular dynamics simulation
long-acting antihyperglycemic
Dependence of the rate-limiting steps in the dark-to-light transition of photosystem II on the lipidic environment of the reaction center
期刊论文
PHOTOSYNTHETICA, 2022, 卷号: 60, 期号: 1, 页码: 147-156
作者:
Magyar, M.
;
Akhtar, P.
;
Sipka, G.
;
Han, W.
;
LI, X.
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  |  
浏览/下载:0/0
  |  
提交时间:2024/03/07
closed state of PSII
conformational chang
dielectric relaxation
light-adapted state of PSII
light-induced changes
proteoliposomes
Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan
期刊论文
CELL RESEARCH, 2021, 页码: 12
作者:
Ling, Shenglong
;
Shi, Pan
;
Liu, Sanling
;
Meng, Xianyu
;
Zhou, Yingxin
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  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan
期刊论文
CELL RESEARCH, 2021
作者:
Ling, Shenglong
;
Shi, Pan
;
Liu, Sanling
;
Meng, Xianyu
;
Zhou, Yingxin
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  |  
浏览/下载:26/0
  |  
提交时间:2021/04/26
Structural insights into human acid-sensing ion channel 1a inhibition by snake toxin mambalgin1
期刊论文
ELIFE, 2020, 卷号: 9
作者:
Sun, Demeng
;
Liu, Sanling
;
Li, Siyu
;
Zhang, Mengge
;
Yang, Fan
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  |  
浏览/下载:28/0
  |  
提交时间:2020/11/30
Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325
作者:
Chang, Rulue
;
Zhang, Xin
;
Qiao, Anna
;
Dai, Antao
;
Belousoff, Matthew J.
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  |  
浏览/下载:82/0
  |  
提交时间:2020/12/24
glucagon receptor
glucagon-like peptide-1 receptor
dual agonist
cryo-electron microscopy
single particle analysis
structure-function
structural biology
peptide 15 (P15)
metabolic disorder
G protein?coupled receptor (GPCR)
glucagon
GLP-1 receptor
Structural basis of G(s) and G(i) recognition by the human glucagon receptor
期刊论文
SCIENCE, 2020, 卷号: 367, 期号: 6484, 页码: 1346-+
作者:
Qiao, Anna
;
Han, Shuo
;
Li, Xinmei
;
Li, Zhixin
;
Zhao, Peishen
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  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
Structural Changes and Antibacterial Activity of Epsilon-poly-L-lysine in Response to pH and Phase Transition and Their Mechanisms
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020, 卷号: 68, 期号: 4, 页码: 1101-1109
作者:
Liu, Jia-Ning
;
Chang, Sen-Lin
;
Xu, Peng-Wei
;
Tan, Ming-Hui
;
Zhao, Bing
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  |  
浏览/下载:8/0
  |  
提交时间:2020/03/24
epsilon-poly-L-lysine
conformation
beta-sheet
pH responsivity
carbamoylated epsilon-PL
antibacterial activity
Broadband terahertz signatures and vibrations of dopamine
期刊论文
ANALYST, 2020, 卷号: 145, 期号: 18, 页码: 6006-6013
作者:
Zhu, ZJ
;
Zhang, JB
;
Song, YS
;
Chang, C
;
Ren, GH
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/09/06
GAS-PHASE
INFRARED-SPECTROSCOPY
RECEPTOR
SPECTRA
NEUROTRANSMITTERS
CONFORMATION
MODES
Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays
期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 16, 期号: 6, 页码: 416-427
作者:
Hou, Tingjun
;
Li, Dan
;
Chang, Shan
;
Xu, Lei
;
Sun, Huiyong
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  |  
浏览/下载:260/0
  |  
提交时间:2019/06/24
Androgen receptor
AR ligand
Virtual screening
AR agonist
AR antagonist
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