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Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15
作者:
Lu, Shaoyong
;
He, Xinheng
;
Yang, Zhao
;
Chai, Zongtao
;
Zhou, Shuhua
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  |  
浏览/下载:33/0
  |  
提交时间:2021/11/04
Relationship between angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and COVID-19 incidence or severe disease
期刊论文
JOURNAL OF HYPERTENSION, 2021, 卷号: 39, 期号: 8, 页码: 1717-1724
作者:
Tse, Gary
;
Zhou, Jiandong
;
Lee, Sharen
;
Wong, Wing Tak
;
Li, Xintao
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  |  
浏览/下载:73/0
  |  
提交时间:2021/08/15
angiotensin receptor blockers
angiotensin-converting enzyme inhibitors
COVID-19 incidence
TWIRLS, a knowledge-mining technology, suggests a possible mechanism for the pathological changes in the human host after coronavirus infection via ACE2 (vol 81, pg 1004, 2020)
期刊论文
DRUG DEVELOPMENT RESEARCH, 2021, 页码: 1
作者:
Niu, Gang
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  |  
浏览/下载:23/0
  |  
提交时间:2021/12/01
coronavirus
cytokine storm
literature mining
renin
angiotensin system
topic inference
Targeted Drugs for Treatment of Pulmonary Arterial Hypertension: Past, Present, and Future Perspectives
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 24, 页码: 15153-15186
作者:
Zheng, Wei
;
Wang, Zhen
;
Jiang, Xiangrui
;
Zhao, Qingjie
;
Shen, Jingshan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
TWIRLS, a knowledge-mining technology, suggests a possible mechanism for the pathological changes in the human host after coronavirus infection via ACE2
期刊论文
DRUG DEVELOPMENT RESEARCH, 2020, 卷号: 81, 期号: 8, 页码: 1004-1018
作者:
Ji, Xiaoyang
;
Tan, Wenting
;
Zhang, Chunming
;
Zhai, Yubo
;
Hsueh, Yiching
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  |  
浏览/下载:45/0
  |  
提交时间:2021/12/01
coronavirus
cytokine storm
literature mining
renin‐
angiotensin system
topic inference
COVID-19 and multiorgan failure: A narrative review on potential mechanisms
期刊论文
JOURNAL OF MOLECULAR HISTOLOGY, 2020, 页码: 16
作者:
Mokhtari, Tahmineh
;
Hassani, Fatemeh
;
Ghaffari, Neda
;
Ebrahimi, Babak
;
Yarahmadi, Atousa
收藏
  |  
浏览/下载:129/0
  |  
提交时间:2020/11/30
COVID-19
SARS-CoV2
Multi-organ failure
Angiotensin-converting enzyme-2
Cytokine storm
Coagulation
The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor
期刊论文
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 45, 期号: 1, 页码: 15-26
作者:
Zhang, Leduo
;
Mao, Yu
;
Gao, Zhiwei
;
Chen, Xiaoyan
;
Li, Xin
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  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
The association between apelin polymorphisms and hypertension in China: A meta-analysis
期刊论文
JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM, 2019, 卷号: 20, 期号: 1
作者:
Wang, Tianyi
;
Liu, Conghe
;
Jia, Lili
;
Ding, Jun
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  |  
浏览/下载:35/0
  |  
提交时间:2019/12/05
Apelin
essential hypertension
single nucleotide polymorphism
rs3761581
rs56204867
meta-analysis
Spironolactone alleviates diabetic nephropathy through promoting autophagy in podocytes
期刊论文
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2019, 卷号: 51, 期号: 4
作者:
Ji, Ying-shi
;
Fan, Ting-ting
;
Dong, Dan
;
Zhang, Li
;
Wu, Shan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
Diabetic nephropathy
Spironolactone
Podocytes
Autophagy
Rennin angiotensin aldosterone system
Decreased Ang-(1-7) and Downregulated Intrarenal RAS May Contribute to the Direct Podocyte Injury With Proteinuria in Preeclampsia
期刊论文
REPRODUCTIVE SCIENCES, 2019, 卷号: 26, 期号: 8
作者:
Zhang, Lihong
;
Niu, Jianying
;
Gu, Yong
;
Chen, Guixiang
;
Jin, Xiaohong
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/12/05
renin-angiotensin system (RAS)
Ang-(1-7)
Mas
podocyte
preeclampsia
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