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CORC

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Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15111-15125
作者:  Zhang, Huimin;  He, Jixiao;  Hu, Guang;  Zhu, Fei;  Jiang, Hao
收藏  |  浏览/下载：35/0  |  提交时间：2022/01/04
D3DistalMutation: a Database to Explore the Effect of Distal Mutations on Enzyme Activity 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2021, 卷号: 61, 期号: 5, 页码: 2499-2508
作者:  Wang, Xiaoyu;  Zhang, Xinben;  Peng, Cheng;  Shi, Yulong;  Li, Huiyu
收藏  |  浏览/下载：13/0  |  提交时间：2021/08/17
Allosteric Regulation of Hsp90 alpha's Activity by Small Molecules Targeting the Middle Domain of the Chaperone 期刊论文
ISCIENCE, 2020, 卷号: 23, 期号: 2, 页码: 46
作者:  Zhou, Chen;  Zhang, Chi;  Zhu, Hongwen;  Liu, Zhijun;  Su, Haixia
收藏  |  浏览/下载：143/0  |  提交时间：2020/07/01
A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer 期刊论文
CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+
作者:  Huang, Ke;  Liang, Qian;  Zhou, Ye;  Jiang, Lu-lu;  Gu, Wei-ming
收藏  |  浏览/下载：77/0  |  提交时间：2020/07/01
3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586
作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang
收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01
Targeting epigenetic machinery: Emerging novel allosteric inhibitors 期刊论文
PHARMACOLOGY & THERAPEUTICS, 2019, 卷号: 204, 页码: 24
作者:  Ye, Fei;  Huang, Jing;  Wang, Hongbo;  Luo, Cheng;  Zhao, Kehao
收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01
Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236
作者:  Duan, Zhe;  Liu, Jingqiu;  Niu, Liping;  Wang, Jun;  Feng, Mingqian
收藏  |  浏览/下载：54/0  |  提交时间：2020/07/01
The Effect of Structural Diversity on Ligand Specificity and Resulting Signaling Differences of Estrogen Receptor alpha 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 6, 页码: 1002-1013
作者:  Xue, Qiao;  Liu, Xian;  Liu, Xiu-Chang;  Pan, Wen-Xiao;  Fu, Jian-Jie
收藏  |  浏览/下载：11/0  |  提交时间：2020/10/21
The inhibitory mechanism of aurintricarboxylic acid targeting serine/threonine phosphatase Stp1 in Staphylococcus aureus: insights from molecular dynamics simulations 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 6, 页码: 850-858
作者:  Liu, Ting-ting;  Yang, Teng;  Gao, Mei-na;  Chen, Kai-xian;  Yang, Song
收藏  |  浏览/下载：10/0  |  提交时间：2020/07/01
Isolation and biochemical characterization of a metagenome-derived 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase gene from subtropical marine mangrove wetland sediments 期刊论文
AMB EXPRESS, 2019, 卷号: 9
作者:  Zhao, Huaxian;  Gao, Hua;  Ji, Kai;  Yan, Bing;  Li, Quanwen
收藏  |  浏览/下载：21/0  |  提交时间：2019/08/19

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