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生态环境研究中心 [12]
水生生物研究所 [8]
兰州大学 [6]
厦门大学 [5]
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武汉大学 [3]
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期刊论文 [45]
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Zebrafish (Danio rerio) TR beta- and TTR-based electrochemical biosensors: Construction and application for the evaluation of thyroid-disrupting activity of bisphenols
期刊论文
ENVIRONMENTAL POLLUTION, 2023, 卷号: 330, 页码: 9
作者:
Li, Yuejiao
;
Zhang, Zhenzhong
;
Wang, Jun
;
Shan, Yeqi
;
Tian, Hua
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2023/12/07
Thyroid-disrupting chemicals
Thyroid hormone receptor beta
Transthyretin
In vitro screening Assay
Electrochemical biosensor
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways
期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:
Wang, Xiaoqing
;
Li, Fei
;
Chen, Jingwen
;
Ji, Chenglong
;
Wu, Huifeng
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/22
Adverse outcome pathway (AOP)
Comparative toxicogenomics database (CTD)
Triphenyl phosphate (TPP)
Molecular dynamics (MD)
Transcriptome analyses
TDCPP mimics thyroid hormones associated with the activation of integrin alpha(v)beta(3) and ERK1/2
期刊论文
CHEMOSPHERE, 2020, 卷号: 256, 页码: 1-9
作者:
Li, Jian
;
Liu, Hedan
;
Li, Na
;
Wang, Jinsheng
;
Song, Liuting
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/09/15
TDCPP
BDCPP
Thyroid disruption
Integrin alpha(v)beta(3)
ERK1/2
德克隆类化合物对甲状腺系统的干扰效应及其分子机制
学位论文
北京: 中国科学院生态环境研究中心, 2020
作者:
朱剑桥
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  |  
浏览/下载:16/0
  |  
提交时间:2021/07/07
德克隆类化合物、甲状腺激素受体、竞争结合、t-screen、报告基因
Dechloranes, Thyroid Hormone Receptor, Ligand Binding Assay, T-screen Assay, Reporter Gene Assay
Competitive binding assays for measuring the binding affinity of thyroid-disrupting chemicals for integrin alpha(v)beta(3)
期刊论文
CHEMOSPHERE, 2020, 卷号: 249, 页码: 1-8
作者:
Li, Jian
;
Liu, Hedan
;
Zuo, Rui
;
Yang, Jie
;
Li, Na
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/09/15
Thyroid-disrupting chemicals
Integrin alpha(v)beta(3)
Competitive binding assay
T4-BSA-F
Tc-99m-3PRGD(2)
Phthalate esters
Evaluation and mechanistic study of chlordecone-induced thyroid disruption: Based on in vivo, in vitro and in silico assays
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 716, 页码: 1-10
作者:
Yang, Lihua
;
Zha, Jinmiao
;
Guo, Yongyong
;
Zhou, Bingsheng
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/09/15
Chlordecone
Thyroid disruption
Rare minnow
GH3 cells
Estrogen receptor
The molecular mechanism of the antagonistic activity of hydroxylated polybrominated biphenyl (OH-BB80) toward thyroid receptor beta
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 卷号: 697, 页码: -
作者:
Zhang, Xiaofang
;
Cui, Shixuan
;
Pan, Liumeng
;
Dong, Wenhua
;
Ma, Mei
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/09/10
Hydroxylated brominated biphenyls
Endocrine disrupting effect
Molecular interactions
Metabolic activation
A comparison of endocrine disruption potential of nonylphenol ethoxylate, vanillin ethoxylate, 4-n-nonylphenol and vanillin in vitro
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 175, 页码: 208-214
作者:
Ji, Xiaoya
;
Li, Na
;
Yuan, Shengwu
;
Zhou, Xiaohong
;
Ding, Fengmei
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/10/23
Nonylphenol ethoxylate
Vanillin ethoxylate
4-n-nonylphenol
Vanillin
Nuclear receptors
Two-hybrid yeast
Mechanism of the Endocrine-Disruptive Effects of Low-Dose Bisphenol A via Transmembrane Receptor
期刊论文
PROGRESS IN CHEMISTRY, 2019, 卷号: 31, 期号: 1, 页码: 167-179
作者:
Zhu, Benzhan
;
Shen, Chen
;
Sheng, Zhiguo
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/10/21
bisphenol A
low-dose effect
G protein-coupled receptor 30
integrin alpha v beta 3
toxic effect
Thyroid Disruption by Bisphenol S Analogues via Thyroid Hormone Receptor beta: in Vitro, in Vivo, and Molecular Dynamics Simulation Study
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2018, 卷号: 52, 期号: 11, 页码: 6617-6625
作者:
Zhuang, Shulin
;
Liu, Weiping
;
Zhang, Chunlong
;
Wang, Jingpeng
;
Xu, Chao
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/06/24
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