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CORC

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Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor selective degradation of nucleolin 期刊论文
MOLECULAR THERAPY-NUCLEIC ACIDS, 2022, 卷号: 30
作者:  Zhang, Lin;  Li, Ling;  Wang, Xia;  Liu, Huimin;  Zhang, Yibin
收藏  |  浏览/下载：20/0  |  提交时间：2022/12/23
S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:  Li, Haobin;  Cai, Maohua;  Cao, Fei;  Yu, Dehua;  Yang, Jing
收藏  |  浏览/下载：11/0  |  提交时间：2022/12/22
Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng
收藏  |  浏览/下载：15/0  |  提交时间：2022/12/23
Structure-aware conditional variational auto-encoder for constrained molecule optimization 期刊论文
PATTERN RECOGNITION, 2022, 卷号: 126, 页码: 9
作者:  Yu, Junchi;  Xu, Tingyang;  Rong, Yu;  Huang, Junzhou;  He, Ran
收藏  |  浏览/下载：17/0  |  提交时间：2022/06/06
Systemic Therapy for Hepatocellular Carcinoma: Chinese Consensus-Based Interdisciplinary Expert Statements 期刊论文
LIVER CANCER, 2022, 卷号: 11
作者:  Sun, Yongkun;  Zhang, Wen;  Bi, Xinyu;  Yang, Zhengqiang;  Tang, Yu
收藏  |  浏览/下载：30/0  |  提交时间：2022/12/23
EGPI-1, a novel eIF4E/eIF4G interaction inhibitor, inhibits lung cancer cell growth and angiogenesis through Ras/MNK/ERK/eIF4E signaling pathway 期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2022, 卷号: 352, 页码: 10
作者:  Qi, Xueju;  Zhang, Shuna;  Chen, Zekun;  Wang, Lijun;  Zhu, Wenyong
收藏  |  浏览/下载：15/0  |  提交时间：2022/07/18
An overview of kinase downregulators and recent advances in discovery approaches 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:  Wang, Beilei;  Wu, Hong;  Hu, Chen;  Wang, Haizhen;  Liu, Jing
收藏  |  浏览/下载：39/0  |  提交时间：2022/01/25
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang
收藏  |  浏览/下载：58/0  |  提交时间：2022/01/18
Transformer-Based Generative Model Accelerating the Development of Novel BRAF Inhibitors 期刊论文
ACS OMEGA, 2021, 卷号: 6, 期号: 49, 页码: 33864-33873
作者:  Yang, Lijuan;  Yang, Guanghui;  Bing, Zhitong;  Tian, Yuan;  Niu, Yuzhen
收藏  |  浏览/下载：16/0  |  提交时间：2022/04/11
Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site 期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452
作者:  Wang, Jiang;  Yang, Dehua;  Cheng, Xi;  Yang, Linlin;  Wang, Zhaohui
收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04

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