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Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity 期刊论文
ISCIENCE, 2021, 卷号: 24, 期号: 11, 页码: 22
作者:  Hu, Lin;  Chen, Fuxian;  Wu, Chao;  Wang, Jun;  Chen, Si-si
收藏  |  浏览/下载:38/0  |  提交时间:2022/01/18
Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 3, 页码: 397-403
作者:  Li, Chunpu;  Hu, Sha-Sha;  Yang, Lisheng;  Wang, Min;  Long, Jian-Dong
收藏  |  浏览/下载:54/0  |  提交时间:2021/05/24
SL010110, a lead compound, inhibits gluconeogenesis via SIRT2-p300-mediated PEPCK1 degradation and improves glucose homeostasis in diabetic mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:  Ren, Yu-ran;  Ye, Yang-liang;  Feng, Ying;  Xu, Ti-fei;  Shen, Yu
收藏  |  浏览/下载:21/0  |  提交时间:2021/05/24
Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5 期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 12, 页码: 18
作者:  Han, Haozhen;  Li, Chunpu;  Li, Man;  Yang, Lisheng;  Zhao, Sen
收藏  |  浏览/下载:35/0  |  提交时间:2020/12/24
Molecular dynamics simulations reveal the mechanism of the interactions between the inhibitors and SIRT2 at atom level 期刊论文
MOLECULAR SIMULATION, 2020, 卷号: 46, 期号: 8, 页码: 638-649
作者:  Wang, Xiaoyu;  Song, Menghua;  Zhao, Shuang;  Li, Huiyu;  Zhao, Qingjie
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/01
Vincristine ablation of Sirt2 induces cell apoptosis and mitophagy via Hsp70 acetylation in MDA-MB-231 cells 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2019, 卷号: 162
作者:  Sun, Fanghui;  Jiang, Xiaoxiao;  Wang, Xuan;  Bao, Yong;  Feng, Guize
收藏  |  浏览/下载:34/0  |  提交时间:2019/12/05
The SIRT2/cMYC Pathway Inhibit Peroxidation-Related Apoptosis In Cholangiocarcinoma Through Metabolic Reprogramming 期刊论文
NEOPLASIA, 2019, 卷号: 21, 期号: 5
作者:  Xu, Lei;  Wang, Lei;  Zhou, Lixing;  Dorfman, Robert Gregory;  Pan, Yida
收藏  |  浏览/下载:34/0  |  提交时间:2019/12/05
Protective role of AGK2 on thioacetamide-induced acute liver failure in mice 期刊论文
LIFE SCIENCES, 2019, 卷号: 230
作者:  Jiao, Fang-Zhou;  Wang, Yao;  Wen-Bin Zhang;  Zhang, Hai-Yue;  Chen, Qian
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/05
Functional genetic variants within the SIRT2 gene promoter in breast cancer 期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2019, 卷号: 12, 期号: 1, 页码: 744-752
作者:  Zhu, Kunbing;  Xu, Can;  Zhang, Jie;  Ma, Shu;  Shi, Peng
收藏  |  浏览/下载:118/0  |  提交时间:2019/12/11
The mimics of N-epsilon-acyl-lysine derived from cysteine as sirtuin inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 14, 页码: 2375-2378
作者:  Wang, Chun;  Wang, Fang;  Chen, Xiaoxue;  Zou, Yefang;  Zhu, Hong
收藏  |  浏览/下载:22/0  |  提交时间:2019/01/08


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