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上海药物研究所 [10]
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期刊论文 [53]
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Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:
Qiao, Shida
;
Feng, Sisi
;
Wu, Zhitao
;
He, Ting
;
Ma, Chen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
TCDD promotes liver fibrosis through disordering systemic and hepatic iron homeostasis
期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2020, 卷号: 395, 页码: 1-8
作者:
Li, Changying
;
Liu, Yingying
;
Dong, Zheng
;
Xu, Ming
;
Gao, Ming
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/09/14
TCDD
Liver fibrosis
Cideb
Hepatocyte apoptosis
Iron deposition
Silver nanoparticles (AgNPs) and AgNO3 perturb the speci fication of human hepatocyte-like cells and cardiomyocytes
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 725, 页码: 1-10
作者:
Hu, Bowen
;
Yin, Nuoya
;
Yang, Renjun
;
Liang, Shengxian
;
Liang, Shaojun
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/09/14
Human embryonic stem cells (hESCs)
Silver nanoparticles (AgNPs)
Developmental toxicity
Hepatocyte-like cells
Cardiomyocytes
Stem cell toxicology
Graphene Oxide Causes Disordered Zonation Due to Differential Intralobular Localization in the Liver
期刊论文
ACS NANO, 2020, 卷号: 14, 期号: 1, 页码: 877-890
作者:
Wu, Yakun
;
Feng, Wenya
;
Liu, Rui
;
Xia, Tian
;
Liu, Sijin
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  |  
浏览/下载:48/0
  |  
提交时间:2021/09/14
liver zonation
zonated accumulation
DNA methylation
mRNA transcription
graphene oxide
A cell lines derived microfluidic liver model for investigation of hepatotoxicity induced by drug-drug interaction
期刊论文
BIOMICROFLUIDICS, 2019, 卷号: 13, 页码: 024101
作者:
Deng, Jiu
;
Zhang, Xiuli
;
Chen, Zongzheng
;
Luo, Yong
;
Lu, Yao
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  |  
浏览/下载:4/0
  |  
提交时间:2019/12/02
Ability testing
Artificial organs
Cell culture
Metabolism
Microfluidics, Artificial liver
Clinical application
Drug metabolisms
Drug-drug interactions
Enzymatic activities
Interaction testing
Micro-fluidic devices
Primary hepatocyte, Drug interactions
肝脏疾病中肝细胞损伤的基底刚度调控和中性粒细胞的迁移动力学
学位论文
北京: 中国科学院大学, 2018
作者:
杨浩
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  |  
浏览/下载:128/0
  |  
提交时间:2018/05/30
基底刚度
肝细胞损伤
血流剪切
肝血窦
中性粒细胞募集
Detection of nanocarrier potentiation on drug induced phospholipidosis in cultured cells and primary hepatocyte spheroids by high content imaging and analysis
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018, 卷号: 348, 页码: 54, 66
作者:
Zhang, Xihui
;
Yang, Liecheng
;
Liu, Yongming
;
Song, Zhentao
;
Zhao, Jian
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  |  
浏览/下载:39/0
  |  
提交时间:2018/12/28
Phospholipidosis
Nanocarrier
Primary hepatocyte
Spheroid
High content screening
Analysis of differentially expressed genes among human hair follicle-derived iPSCs, induced hepatocyte-like cells, and primary hepatocytes
期刊论文
STEM CELL RESEARCH & THERAPY, 2018, 卷号: 9
作者:
Xu, Ziran
;
He, Xia
;
Shi, Xu
;
Xia, Yuhan
;
Liu, Xiaomei
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
Induced pluripotent stem cells
Stem cell differentiation
Hepatocyte-like cells
Differentially expressed genes
Microarray analysis
In Vitro Expansion of Primary Human Hepatocytes with Efficient Liver Repopulation Capacity
期刊论文
CELL STEM CELL, 2018, 卷号: 23, 期号: 6, 页码: 806-+
作者:
Zhang, Kun
;
Peng, Luying
;
Zhang, Ludi
;
Liu, Wenming
;
Ma, Xiaolong
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2019/04/28
Long-term Culture
Stem-cells
Gene-expression
Conversion
Fibroblasts
Progenitors
Arrest
Wnt
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