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Cost-effective purification process development for chimeric hepatitis B core (HBc) virus-like particles assisted by molecular dynamic simulation
期刊论文
ENGINEERING IN LIFE SCIENCES, 2021, 页码: 15
作者:
Zhang, Bingyang
;
Yin, Shuang
;
Wang, Yingli
;
Su, Zhiguo
;
Bi, Jingxiu
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/08/31
hepatitis B core
molecular dynamic simulation
protein characterization
protein purification
virus‐
like particle
Performance of agarose and gigaporous chromatographic media as function of pore-to-adsorbate size ratio over wide span from ovalbumin to virus like particles
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2021, 卷号: 1638, 页码: 12
作者:
Yang, Yanli
;
Yu, Mengran
;
Ma, Guanghui
;
Su, Zhiguo
;
Zhang, Songping
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/03/29
Pore size
Protein size
Ion-exchange media
Ratio of pore-to-adsorbate size
Adsorption capacity
Adsorption kinetics
In vitro preparation of uniform and nucleic acid free hepatitis B core particles through an optimized disassembly-purification-reassembly process
期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2021, 卷号: 178, 页码: 7
作者:
Zhang, Yao
;
Liu, Yongdong
;
Zhang, Bingyang
;
Yin, Shuang
;
Li, Xiunan
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2021/08/31
Hepatitis B core (HBc)
Uniform VLPs
Nucleic acid removal
Disassembly-purification-reassembly
Engineered hepatitis B core virus-like particle carrier for precise and personalized Alzheimer's disease vaccine preparation via fixed-point coupling
期刊论文
APPLIED MATERIALS TODAY, 2020, 卷号: 19, 页码: 16
作者:
Ji, Mei
;
Xie, Xi-xiu
;
Liu, Dong-qun
;
Lu, Shuai
;
Zhang, Ling-xiao
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/09/22
Alzheimer's disease
Virus-like particles (VLPs)
B cell epitope peptide
SpyCatcher/SpyTag
Th2-type immune response
HBc-based virus-like particle assembly from inclusion bodies using 2-methyl-2, 4-pentanediol
期刊论文
PROCESS BIOCHEMISTRY, 2020, 卷号: 89, 页码: 233-237
作者:
Zhang, Yao
;
Yin, Shuang
;
Zhang, Bingyang
;
Bi, Jingxiu
;
Liu, Yongdong
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  |  
浏览/下载:38/0
  |  
提交时间:2020/05/06
Virus-like particle (VLP)
Hepatitis B virus core antigen (HBc)
Inclusion body
Assembly
Sodium dodecyl sulfate (SDS)
2-methyl-2, 4-pentanediol (MPD)
Development of meningococcal polysaccharide conjugate vaccine that can elicit long-lasting and strong cellular immune response with hepatitis B core antigen virus-like particles as a novel carrier protein
期刊论文
VACCINE, 2019, 卷号: 37, 期号: 7, 页码: 956-964
作者:
Xu, Lingling
;
Li, Zhengjun
;
Su, Zhiguo
;
Yang, Yanli
;
Ma, Guanghui
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  |  
浏览/下载:69/0
  |  
提交时间:2019/04/03
Neisseria meningitidis
Conjugate vaccine
Hepatitis B core antigen
Virus-like particles
The Antiresection Activity of the X Protein Encoded by Hepatitis Virus B
期刊论文
HEPATOLOGY, 2019, 卷号: 69, 期号: 6, 页码: 2546-2561
作者:
Ren, Laifeng
;
Zeng, Ming
;
Tang, Zizhi
;
Li, Mingyuan
;
Wang, Xiaojun
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  |  
浏览/下载:19/0
  |  
提交时间:2021/11/04
A two-step heat treatment of cell disruption supernatant enables efficient removal of host cell proteins before chromatographic purification of HBc particles
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2018, 卷号: 1581, 页码: 71-79
作者:
Li, Zhengjun
;
Wei, Jiangxue
;
Yang, Yanli
;
Liu, Lili
;
Ma, Guanghui
收藏
  |  
浏览/下载:260/0
  |  
提交时间:2019/04/03
Hepatitis b Core Protein
Thermal Stability
Particles
Purification
Host Cell Protein
Chromatography
Effect of Pore Structure on Protein Capacity in Macroporous Polymer Chromatographic Supports
期刊论文
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2018, 卷号: 39, 期号: 12, 页码: 2673-2678
作者:
Li Heng
;
Wang Shaoyun
;
Fang Jiaxuan
;
Zhao Lan
;
Jin Haibo
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2019/04/03
Macroporous Polymer Microsphere
Chromatographic Media
Protein Capactiy
High Through-put
Amino acid substitutions q129n and t131n/m133t in hepatitis b surface antigen (hbsag) interfere with the immunogenicity of the corresponding hbsag or viral replication ability
期刊论文
Virus research, 2018, 卷号: 257, 页码: 33-39
作者:
Kang, Yaoyue
;
Li, Fahong
;
Guo, Hongying
;
Yang, Sisi
;
Zhang, Yongmei
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/05/08
Hbsag
Q129n
T131n/m133t
Antigenicity
Immunogenicity
Hbv replication
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