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浏览/检索结果: 共12条，第1-10条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 First unequivocal identification of the critical acyl radicals from the anti- tuberculosis drug isoniazid and its hydrazide analogs by complementary applications of ESR spin-trapping and HPLC/MS methods 期刊论文 FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 154, 页码: 1-8 作者:  Qin, Li;  Huang, Chun-Hua;  Mao, Li;  Shao, Bo;  Zhu, Ben-Zhan 收藏  |  浏览/下载：34/0  |  提交时间：2021/09/14 Isoniazid  Hydrazides  Carbon-centered acyl radicals  ESR spin-trapping/HPLC/MS  N-tert-butyl-alpha-phenylnitrone (PBN)  NAD(+) adducts   An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids 期刊论文 FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 146, 页码: 150-159 作者:  Zhu, Ben-Zhan;  Xu, Dan;  Qin, Li;  Huang, Chun-Hua;  Xie, Lin-Na 收藏  |  浏览/下载：33/0  |  提交时间：2021/09/14 N-centered amidyl radical  Nitroxide radical  Hydrogen-abstraction  Tetrachloroquinoid compounds  N-alkyl hydroxamic acids   Unexpected activation of N-alkyl hydroxamic acids to produce reactive N-centered free radicals and DNA damage by carcinogenic chlorinated quinones under normal physiological conditions 期刊论文 FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 146, 页码: 70-78 作者:  Huang, Chun-Hua;  Xu, Dan;  Qin, Li;  Tang, Tian-Shu;  Shan, Guo-Qiang 收藏  |  浏览/下载：18/0  |  提交时间：2021/09/14 N-alkyl hydroxamic acids  N-centered radicals  Chlorinated quinones  Carbon-nitrogen bonding conjugate  DNA adducts   Molecular mechanism for the activation of the anti-tuberculosis drug isoniazid by Mn(III): First detection and unequivocal identification of the critical N-centered isoniazidyl radical and its exact location 期刊论文 FREE RADICAL BIOLOGY AND MEDICINE, 2019, 卷号: 143, 页码: 232-239 作者:  Qin, Li;  Huang, Chun-Hua;  Xu, Dan;  Xie, Lin-Na;  Shao, Jie 收藏  |  浏览/下载：14/0  |  提交时间：2020/09/10 Isoniazid  Mn(III)(Acetate) 3  Isoniazidyl radical  Distal-nitrogen of the hydrazine group  Diisonicotinyl hydrazine   An unusual double radical homolysis mechanism for the unexpected activation of the aldoxime nerve-agent antidotes by polyhalogenated quinoid carcinogens under normal physiological conditions 期刊论文 FREE RADICAL BIOLOGY AND MEDICINE, 2019, 卷号: 130, 页码: 1-7 作者:  Xie, Lin-Na;  Shao, Jie;  Huang, Chun-Hua;  Li, Feng;  Xu, Dan 收藏  |  浏览/下载：2/0  |  提交时间：2020/10/21 Radical homolysis mechanism  Iminyl radical  Tetrachloro-1, 4-benzoquinone (TCBQ)  Pyridinium aldoximes  Nerve-agent antidotes  Polyhalogenated quinoid carcinogens   环状异羟肟酸及衍生物与多卤代醌反应机理研究 学位论文 博士, 北京: 中国科学院研究生院, 2016 作者:  李锋 收藏  |  浏览/下载：130/0  |  提交时间：2017/07/11 四氯苯醌，N-羟基吡啶酮，N-羟基吡啶硫酮，N-羟基邻苯二甲酰亚胺， 糖精钠  Tetrachloro-1,4-benzoquinone (TCBQ), N-hydroxypyridone (NHP), N-hydroxypyrithione (NHPT), N-hydroxyphthalimide (NHPI), saccharin sodium   致癌性卤代醌介导的脂质氢过氧化物13-HPODE分解的分子反应机理研究 学位论文 博士, 北京: 中国科学院研究生院, 2013 覃浩 收藏  |  浏览/下载：213/0  |  提交时间：2014/09/03 卤代醌  2  5-二氯-1  4苯醌  13-过氧羟基-9  11-十八碳二烯酸  电子自旋共振-自旋捕获技术  脂质烷烃自由基  4-羟基-2-壬烯醛  醌-烷氧脂质耦合产物  Halogenated quinones  2  5-dichloro-1  4-benzoquinone  13-Hydroperoxy-9  11-octadecadienoic acid  ESR spin-trapping  Lipid alkyl radicals  4-Hydroxy-2-nonenal  Quinone-lipid alkoxyl conjugates   致癌性卤代醌介导的新型自由基与重排反应分子机理研究 学位论文 博士, 北京: 中国科学院研究生院, 2013 黄春华 收藏  |  浏览/下载：80/0  |  提交时间：2014/08/19 醌酮自由基  氮自由基  ESR 自旋捕获  新型Claisen 重排  两性离子 断裂  Quinone ketoxy radical  Nitrogen radical  ESR spin-trapping  New Claisen rearrangement  Zwitt-azido cleavage   Molecular mechanism of metal-independent decomposition of lipid hydroperoxide 13-HPODE by halogenated quinoid carcinogens 期刊论文 FREE RADICAL BIOLOGY AND MEDICINE, 2013, 卷号: 63, 页码: 459-466 Qin, Hao; Huang, Chun-Hua; Mao, Li; Xia, Hai-Ying; Kalyanaraman, Balaraman; Shao, Jie; Shan, Guo-Qiang; Zhu, Ben-Zhan 收藏  |  浏览/下载：16/0  |  提交时间：2014/06/06 The first purification and unequivocal characterization of the radical form of the carbon-centered quinone ketoxy radical adduct 期刊论文 CHEMICAL COMMUNICATIONS, 2013, 卷号: 49, 期号: 57, 页码: 6436-6438 Huang, Chun-Hua; Shan, Guo-Qiang; Mao, Li; Kalyanaraman, Balaraman; Qin, Hao; Ren, Fu-Rong; Zhu, Ben-Zhan 收藏  |  浏览/下载：16/0  |  提交时间：2014/06/06