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上海药物研究所 [2]
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期刊论文 [11]
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Revealing the Positive Binding Cooperativity Mechanism between the Orthosteric and the Allosteric Antagonists of CCR2 by Metadynamics and Gaussian Accelerated Molecular Dynamics Simulations
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 4, 页码: 628-637
作者:
An, Xiaoli
;
Bai, Qifeng
;
Bing, Zhitong
;
Liu, Hongli
;
Zhang, Qianqian
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/01/18
CC chemokine receptor 2
orthosteric antagonist
allosteric antagonist
binding cooperativity
metadynamics simulation
Gaussian accelerated MD simulation
Integrin alpha 4 beta 7 switches its ligand specificity via distinct conformer-specific activation
期刊论文
JOURNAL OF CELL BIOLOGY, 2018, 卷号: 217, 期号: 8, 页码: 2799-2812
作者:
Wang, ShiHui
;
Sun, Hao
;
Ge, GaoXiang
;
Chen, JianFeng
;
Wu, ChenYu
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/04/28
Selectin Glycoprotein Ligand-1
Cell-adhesion Molecule-1
Force Spectroscopy
P-selectin
Binding-sites
Structural Specializations
Neutrophil Adhesion
Chemokine Receptors
Crystal-structure
Domains
Identification and expression analysis of an atypical chemokine receptor-2 (ACKR2)/CC chemokine binding protein-2 (CCBP2) in rainbow trout (Oncorhynchus mykiss)
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2015, 卷号: 44, 期号: 2, 页码: 389-398
作者:
Qi, Zhitao
;
Jiang, Yousheng
;
Holland, Jason W.
;
Nie, Pin
;
Secombes, Christopher J.
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  |  
浏览/下载:25/0
  |  
提交时间:2015/09/10
Rainbow trout Oncorhynchus mykiss
Atypical chemokine receptor-2 (ACKR2)
CC chemokine binding protein-2 (CCBP2)
Expression
Infection
Progress in Studies of Structure, Mechanism and Antagonists Interaction of GPCR Co-Receptors for HIV
期刊论文
CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 2014, 卷号: 15, 期号: 10, 页码: 938-950
作者:
Zhong, Bing
;
Zhen, Yunmei
;
Qin, Guangrong
;
Yang, Huaiyu
;
Jiang, Hualiang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
CCR5
computational methods
crystal structure
CXCR4
HIV
small molecular antagonists
Milligram Production and Biological Activity Characterization of the Human Chemokine Receptor CCR3
期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 6, 页码: 1
作者:
Wang, Mingqing
;
Ge, Baosheng
;
Li, Renmin
;
Wang, Xiaoqiang
;
Lao, Jun
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2015/11/02
Expression of Ephrin Receptors and Ligands in Postmortem Brains of HIV-Infected Subjects With and Without Cognitive Impairment
期刊论文
JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2013, 卷号: 8, 期号: 1, 页码: 333-344
Yuferov, Vadim
;
Ho, Ann
;
Morgello, Susan
;
Yang, Yaning
;
Ott, Jurg
;
Kreek, Mary Jeanne
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2015/06/26
HIV dementia
Human postmortem brain
Ephrin receptors and ligands
Chemokine receptors and ligands
Neurocognitive impairment
Association of Polymorphisms of the Mu Opioid Receptor Gene with the Severity of HIV Infection and Response to HIV Treatment
期刊论文
JOURNAL OF INFECTIOUS DISEASES, 2012, 卷号: 205, 期号: 11, 页码: 1745-1756
Proudnikov, Dmitri
;
Randesi, Matthew
;
Levran, Orna
;
Crystal, Howard
;
Dorn, Magdalena
;
Ott, Jurg
;
Ho, Ann
;
Kreek, Mary Jeanne
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2015/06/23
CCR3, CCR2A and macrophage inflammatory protein (MIP)-1 alpha, monocyte chemotactic protein-1 (MCP-1) in the mouse hippocampus during and after pilocarpine-induced status epilepticus (PISE)
期刊论文
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 2009, 卷号: 35, 期号: 5
作者:
Xu, J. H.
;
Long, L.
;
Tang, Y. C.
;
Zhang, J. T.
;
Hu, H. T.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/04
chemokine receptors
ligands
hippocampus
status epilpticus epilepsy
CCR3, CCR2A and macrophage inflammatory protein (MIP)-1 alpha, monocyte chemotactic protein-1 (MCP-1) in the mouse hippocampus during and after pilocarpine-induced status epilepticus (PISE)
期刊论文
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 2009, 卷号: 35, 期号: 5, 页码: 496-514
作者:
Xu, J. H.
;
Long, L.
;
Tang, Y. C.
;
Zhang, J. T.
;
Hu, H. T.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/18
chemokine receptors
hippocampus
ligands
status epilpticus epilepsy
Development of a universal high-throughput calcium assay for G-protein-coupled receptors with promiscuous G-protein G alpha 15/16
期刊论文
ACTA PHARMACOLOGICA SINICA, 2008, 卷号: 29, 期号: 4, 页码: 507-516
作者:
Zhu, Ting
;
Fang, Li-yan
;
Xie, Xin
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
G-protein-coupled receptors
G-protein
G alpha 15/16
high-throughput screening
calcium assay
GTP gamma S binding
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