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Up-regulation of glycolipid transfer protein by bicyclol causes spontaneous restriction of hepatitis C virus replication
期刊论文
Acta Pharmaceutica Sinica B, 2019
作者:
Menghao Huang
;
Hu Li
;
Rong Xue
;
Jianrui Li
;
Lihua Wang
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/12/13
Bicyclol
Hepatitis
C
virus
Glycolipid
transfer
protein
Host
restrictive
factor
Protein
interaction
Up-regulation of glycolipid transfer protein by bicyclol causes spontaneous restriction of hepatitis C virus replication
期刊论文
2019, 卷号: 9, 期号: 4, 页码: 769-781
作者:
Huang, Meng-Hao
;
Li, Hu
;
Xuu, Rong
;
Li, Jianrui
;
Wang, Lihua
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/01/03
Bicyclol
Hepatitis C virus
Glyeolipid transfer protein
Host restrictive factor
Protein interaction
Protective effects of a novel water-soluble biphenyl compound WLP-S-14 against acute-on-chronic liver failure in rats
期刊论文
2019, 卷号: 21, 期号: 9, 页码: 928-938
作者:
Wang, Shao-Yuan
;
Li, Mei
;
Miao, Lu-Yang
;
Wu, Song
;
Tong, Yuan-Feng
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
WLP-S-14
bicyclol
biphenyl
acute-on-chronic liver failure
Evaluation of pharmacokinetic interactions between bicyclol and co-administered drugs in rat and human liver microsomes in vitro and in rats in vivo
期刊论文
2019, 卷号: 49, 期号: 8, 页码: 987-994
作者:
Yang, Shu
;
Hu, Jinping
;
Li, Yan
;
Zhao, Zhigang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Bicyclol
co-administered drugs
drug-drug interactions
CYP3A
pharmacokinetics
Genotoxicity and Embryotoxicity Study of Bicyclol Methyl Ether, Main Impurity in Bicyclol
期刊论文
2018
作者:
Zhang Qian-Qian
;
Li Qiang
;
Dong Lin
;
Li Wan-Fang
;
Li Chao
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
Ames test
bicyclol methyl ether
chromosome aberration test
embryotoxicity
genotoxicity
zebrafish
Bicyclol Attenuates Liver Inflammation Induced by Infection of Hepatitis C Virus via Repressing ROS-Mediated Activation of MAPK/NF-kappa B Signaling Pathway
期刊论文
2018, 卷号: 9, 页码: 1438
作者:
Li, Hu
;
Li, Jian-Rui
;
Huang, Meng-Hao
;
Chen, Jin-Hua
;
Lv, Xiao-Qin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
bicyclol
hepatitis C virus
anti-inflammatory therapy
inflammatory factor
oxidative stress
A Multicenter and Randomized Controlled Trial of Bicyclol in the Treatment of Statin-Induced Liver Injury
期刊论文
2017, 卷号: 23, 页码: 5760-5766
作者:
Wu Naqiong
;
Wang Liansheng
;
Han Zhanying
;
Guo Yuanlin
;
Zhu Chenggang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Alanine Transaminase
Drug-Induced Liver Injury
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Protective Effect of Bicyclol on Anti-Tuberculosis Drug Induced Liver Injury in Rats
期刊论文
2017, 卷号: 22, 期号: 4
作者:
Liu Xin
;
Zhao Manman
;
Mi Jiaqi
;
Chen Hui
;
Sheng Li
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/04
bicyclol
isoniazid
rifampicin
pyrazinamide
oxidative stress
CYP2E1
cytokines
mitochondrial dysfunction
HGF
Bicyclol protects cardiomyocytes from apoptosis in ischemia/reperfusion injury via inhibition of TLR4/NF-kappa B pathway
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2016, 卷号: 9, 期号: 11
作者:
Guo, Xin
;
Jiang, Hong
;
Chen, Jing
;
Zhang, Bo-Fang
;
Hu, Qi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Bicyclol
myocardial ischemia/reperfusion
apoptosis
TLR4
NF-kappa B
Bicyclol promotes toll-like 2 receptor recruiting inosine 5-monophosphate dehydrogenase II to exert its anti-inflammatory effect
期刊论文
2016, 卷号: 18, 期号: 5, 页码: 475-485
作者:
Zhang, You-Wen
;
Guo, Yan-Shen
;
Bao, Xiu-Qi
;
Sun, Hua
;
Zhang, Dan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/04
Bicyclol
IMPDH II
TLR2
lymphocytes
NF-B
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