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浏览/检索结果: 共9条，第1-9条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择发表日期升序发表日期降序提交时间升序提交时间降序题名升序题名降序作者升序作者降序 Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties 期刊论文 BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 13 作者:  Jiang, Bo;  Luo, Jiao;  Guo, Shuju;  Wang, Lijun 收藏  |  浏览/下载：31/0  |  提交时间：2021/05/11 Type 2 diabetes mellitus  Protein tyrosine phosphatase 1B inhibitors  Thiazolidinedione  Insulin signaling  Anti-diabetic activities   Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides 期刊论文 BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480 作者:  Luo, Jiao;  Zheng, Meiling;  Jiang, Bo;  Li, Chao;  Guo, Shuju 收藏  |  浏览/下载：136/0  |  提交时间：2020/09/29 bromophenol  PTP1B inhibitor  selectivity  cell permeability  oral bioavailability   Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice 期刊论文 MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850 作者:  Li, Chao;  Luo, Jiao;  Guo, Shuju;  Jia, Xiaoling;  Guo, Chuanlong 收藏  |  浏览/下载：73/0  |  提交时间：2019/08/28 type 2 diabetes mellitus  protein tyrosine phosphatase 1B  insulin resistance  hypoglycemic activity  dyslipidemia   Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185 作者:  Li, Xiangqian;  Xu, Qi;  Li, Chao;  Luo, Jiao;  Li, Xiuxue 收藏  |  浏览/下载：59/0  |  提交时间：2019/05/15 Anti-diabetic  PTP1B inhibitor  Selectivity  BKS db mice  Toxicity   CYC27 Synthetic Derivative of Bromophenol from Red Alga Rhodomela confervoides: Anti-Diabetic Effects of Sensitizing Insulin Signaling Pathways and Modulating RNA Splicing-Associated RBPs 期刊论文 MARINE DRUGS, 2019, 卷号: 17, 期号: 1, 页码: 15 作者:  Luo, Jiao;  Jiang, Bo;  Li, Chao;  Jia, Xiaoling;  Shi, Dayong 收藏  |  浏览/下载：58/0  |  提交时间：2019/08/28 brominated organic compounds  hypoglycemic activity  insulin-sensitizing effect  RBPs  RNA splicing   Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 166, 页码: 178-185 作者:  Li, Xiangqian;  Xu, Qi;  Li, Chao;  Luo, Jiao;  Li, Xiuxue 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/11 Anti-diabetic  PTP1B inhibitor  Selectivity  BKS db mice  Toxicity   Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice 期刊论文 MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850 作者:  Li, Chao;  Luo, Jiao;  Guo, Shuju;  Jia, Xiaoling;  Guo, Chuanlong 收藏  |  浏览/下载：7/0  |  提交时间：2019/12/11 type 2 diabetes mellitus  protein tyrosine phosphatase 1B  insulin  resistance  hypoglycemic activity  dyslipidemia   Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor 期刊论文 BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 1, 页码: 140-153 作者:  Luo, Jiao;  Xu, Qi;  Jiang, Bo;  Zhang, Renshuai;  Jia, Xiaoling 收藏  |  浏览/下载：43/0  |  提交时间：2019/08/20 Discovery of novel PTP1B inhibitors with antihyperglycemic activity 期刊论文 ACTA PHARMACOLOGICA SINICA, 2010, 卷号: 31, 期号: 8, 页码: 1005-1012 作者:  Liu, Zhang;  Chai, Qian;  Li, Yuan-yuan;  Shen, Qiang;  Ma, Lan-ping 收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 protein tyrosine phosphatases (PTPs)  diabetes  antihyperglycemic activity  drug screening