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Iron dysregulates APP processing accompanying with sAPP alpha cellular retention and beta-secretase inhibition in rat cortical neurons 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 177-183
作者:  Chen, Yu-ting;  Chen, Wu-yan;  Huang, Xiao-tian;  Xu, Ye-chun;  Zhang, Hai-yan
收藏  |  浏览/下载:33/0  |  提交时间:2019/01/08
Visualization of Alzheimer's Disease Related alpha-/beta-/gamma-Secretase Ternary Complex by Bimolecular Fluorescence Complementation Based Fluorescence Resonance Energy Transfer 期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11, 期号: 1, 页码: 431
作者:  Wang, Xin;  Pei, Gang
收藏  |  浏览/下载:25/0  |  提交时间:2019/04/28
alpha-Synuclein stimulation of monoamine oxidase-B and legumain protease mediates the pathology of Parkinson's disease 期刊论文
EMBO JOURNAL, 2018, 卷号: 37, 期号: 12
作者:  Kang, Seong Su;  Ahn, Eun Hee;  Zhang, Zhentao;  Liu, Xia;  Manfredsson, Fredric P.
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/05
PLGA nanoparticles modified with a BBB-penetrating peptide co-delivering A beta generation inhibitor and curcumin attenuate memory deficits and neuropathology in Alzheimer's disease mice 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 46, 页码: 81001-81013
作者:  Huang, Na;  Lu, Shuai;  Liu, Xiao-Ge;  Zhu, Jie;  Wang, Yu-Jiong
收藏  |  浏览/下载:33/0  |  提交时间:2017/11/27
Small molecule lx2343 ameliorates cognitive deficits in ad model mice by targeting both amyloid beta production and clearance 期刊论文
Acta pharmacologica sinica, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:  Guo, Xiao-dan;  Sun, Guang-long;  Zhou, Ting-ting;  Xu, Xin;  Zhu, Zhi-yuan
收藏  |  浏览/下载:37/0  |  提交时间:2019/05/09
Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid beta production and clearance 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1281-1297
作者:  Guo, Xiao-dan;  Sun, Guang-long;  Zhou, Ting-ting;  Xu, Xin;  Zhu, Zhi-yuan
收藏  |  浏览/下载:13/0  |  提交时间:2019/01/08
Targeting the gamma-/beta-secretase interaction reduces beta-amyloid generation and ameliorates Alzheimer's disease-related pathogenesis 期刊论文
CELL DISCOVERY, 2015, 卷号: 1
作者:  Cui, Jin;  Wang, Xiaoyin;  Li, Xiaohang;  Wang, Xin;  Zhang, Chenlu
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Trafficking regulation of proteins in Alzheimer's disease 期刊论文
http://dx.doi.org/10.1186/1750-1326-9-6, 2014
Jiang, Shangtong; Li, Yanfang; Zhang, Xian; Bu, Guojun; Xu, Huaxi; Zhang, Yun-wu; 卜国军; 许华曦; 张云武
收藏  |  浏览/下载:3/0  |  提交时间:2015/07/22
SCG10 promotes non-amyloidogenic processing of amyloid precursor protein by facilitating its trafficking to the cell surface 期刊论文
human molecular genetics, 2013
Wang, Jingjing; Shan, Chunyan; Cao, Wenyuan; Zhang, Chen; Teng, Junlin; Chen, Jianguo
收藏  |  浏览/下载:3/0  |  提交时间:2015/11/13
Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 8, 页码: 613-621
作者:  Li Xiaoman;  Hong Lin;  Coughlan Kathleen;  Wang Liang;  Cao Liu
收藏  |  浏览/下载:1/0  |  提交时间:2021/02/02


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