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Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng
收藏  |  浏览/下载:93/0  |  提交时间:2021/11/04
A rapid and convenient derivatization method for quantitation of short-chain fatty acids in human feces by ultra-performance liquid chromatography/tandem mass spectrometry 期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2020, 卷号: 34, 期号: 9, 页码: 11
作者:  Fu, Huan;  Zhang, Qing-li;  Huang, Xiao-wu;  Ma, Zheng-hua;  Zheng, Xiao-li
收藏  |  浏览/下载:31/0  |  提交时间:2020/07/01
Synthesis and Cdc25B/PTP1B Inhibitory Activity Evaluation of Novel Acylhydrazone Derivatives Containing Carbazole Moity 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 39, 期号: 2, 页码: 491-499
作者:  Li Yingjun;  Wang Siyuan;  Jin Kun;  Gao Lixin;  Sheng Li
收藏  |  浏览/下载:17/0  |  提交时间:2020/07/01
Synthesis and Cell Division Cycle 25B Phosphatase/Protein Tyrosine Phosphatase 1B Inhibitory Activity Evaluation of Novel Acylthiourea Derivatives 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 38, 期号: 5, 页码: 1242-1250
作者:  Li Yingjun;  Wang Siyuan;  Jin Kun;  Gao Lixin;  Sheng Li
收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08
Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 143, 页码: 33-47
作者:  Xu, Yi-xiang;  Wang, Huan;  Li, Xiao-kang;  Dong, Sheng-nan;  Liu, Wen-wen
收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08
The metabolic ER stress sensor IRE1 alpha suppresses alternative activation of macrophages and impairs energy expenditure in obesity 期刊论文
NATURE IMMUNOLOGY, 2017, 卷号: 18, 期号: 5, 页码: 519-529
作者:  Shan, Bo;  Wang, Xiaoxia;  Wu, Ying;  Xu, Chi;  Xia, Zhixiong
收藏  |  浏览/下载:44/0  |  提交时间:2019/01/08
Synthesis and Cell Division Cycle 25B Phosphatase and Protein Tyrosine Phosphatase 1B Inhibitory Activity Evaluation of Novel 3,6-Disubstituted Triazolothiadiazole Derivatives 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 37, 期号: 2, 页码: 485-495
作者:  Li Yingjun;  Li Jiyang;  Peng Lina;  Gao Lixin;  Jin Kun
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Downregulation of stathmin 1 in human gallbladder carcinoma inhibits tumor growth in vitro and in vivo 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:  Wang, Jiwen;  Yao, Yanli;  Ming, Yue;  Shen, Sheng;  Wu, Nan
收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
Design, synthesis and biological evaluation of bisthiazole-based trifluoromethyl ketone derivatives as potent HDAC inhibitors with improved cellular efficacy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 112, 页码: 81-90
作者:  Gong, Chao-Jun;  Gao, An-Hui;  Zhang, Yang-Ming;  Su, Ming-Bo;  Chen, Fei
收藏  |  浏览/下载:22/0  |  提交时间:2019/01/08
Protein Kinase A Rescues Microtubule Affinity-regulating Kinase 2-induced Microtubule Instability and Neurite Disruption by Phosphorylating Serine 409 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 卷号: 290, 期号: 5, 页码: 3149-3160
作者:  Deng, Si-Si;  Wu, Le-Yu;  Wang, Ya-Chao;  Cao, Peng-Rong;  Xu, Lei
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08


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