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科研机构
上海药物研究所 [41]
内容类型
期刊论文 [40]
会议论文 [1]
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2021 [7]
2020 [7]
2019 [2]
2017 [1]
2016 [2]
2015 [1]
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Amygdalar k-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence
期刊论文
CELL REPORTS, 2021, 卷号: 37, 期号: 5, 页码: 21
作者:
Zan, Gui-Ying
;
Wang, Yu-Jun
;
Li, Xue-Ping
;
Fang, Jun-Fan
;
Yao, Song-Yu
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2021/12/16
A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies
期刊论文
MOLECULAR CELL, 2021, 卷号: 81, 期号: 19, 页码: 4076-+
作者:
Liu, Zhiwei
;
Liu, Yingluo
;
Qian, Lili
;
Jiang, Shangwen
;
Gai, Xiameng
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/12/01
Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:
He, Qian
;
Wei, Yuanyuan
;
Liu, Xiao
;
Ye, Rongrong
;
Kong, Linghui
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2021/11/04
Ketamine activated glutamatergic neurotransmission by GABAergic disinhibition in the medial prefrontal cortex
期刊论文
NEUROPHARMACOLOGY, 2021, 卷号: 194, 页码: 10
作者:
Zhang, Bing
;
Yang, Xili
;
Ye, Luyu
;
Liu, Rui
;
Ye, Binglu
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/08/17
A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Ren, Peng-xuan
;
Shang, Wei-juan
;
Yin, Wan-chao
;
Ge, Huan
;
Wang, Lin
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  |  
浏览/下载:85/0
  |  
提交时间:2021/06/11
SARS-CoV-2 inhibitors
RdRp
host ribosome
Virus RNA
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:
Liu, Xiao
;
Jiang, Shuang
;
Kong, Linghui
;
Ye, Rongrong
;
Xiao, Li
收藏
  |  
浏览/下载:114/0
  |  
提交时间:2021/05/24
Morphinans
arylacetamidyl substituent
kappa opioid receptor modulators
structure-activity relationships
Quantitative proteomics reveals Shexiang Baoxin Pill exerts cardioprotective effects by preserving energy metabolism in a rat model of myocardial infarction
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 266, 页码: 10
作者:
Yu, Feng
;
Yu, Yue
;
Tian, Saisai
;
Zhou, Yanting
;
Chen, Xiangling
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/05/24
Shexiang baoxin pill
Cardiovascular disease
LC-MS/MS
Quantitative proteomics
Energy metabolism
Repeated Nitrous Oxide Exposure Exerts Antidepressant-Like Effects Through Neuronal Nitric Oxide Synthase Activation in the Medial Prefrontal Cortex
期刊论文
FRONTIERS IN PSYCHIATRY, 2020, 卷号: 11, 页码: 11
作者:
Liu, Wei
;
Li, Qian
;
Ye, Binglu
;
Cao, Hang
;
Shen, Fuyi
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/12/21
nitrous oxide (N2O)
depression
mPFC
burst firing
neuronal nitric oxide synthase (nNOS)
BDNF
Repeated Nitrous Oxide Exposure Exerts Antidepressant-Like Effects Through Neuronal Nitric Oxide Synthase Activation in the Medial Prefrontal Cortex
期刊论文
FRONTIERS IN PSYCHIATRY, 2020, 卷号: 11, 页码: 11
作者:
Liu, Wei
;
Li, Qian
;
Ye, Binglu
;
Cao, Hang
;
Shen, Fuyi
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/21
nitrous oxide (N2O)
depression
mPFC
burst firing
neuronal nitric oxide synthase (nNOS)
BDNF
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Su, Hai-xia
;
Yao, Sheng
;
Zhao, Wen-feng
;
Li, Min-jun
;
Liu, Jia
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2020/12/24
SARS-CoV-2
3CL protease
traditional Chinese medicines
Shuanghuanglian oral liquid
baicalin
baicalein
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