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科研机构
上海药物研究所 [17]
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期刊论文 [17]
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2021 [2]
2019 [2]
2018 [1]
2017 [1]
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Rhodomeroterpene alleviates macrophage infiltration and the inflammatory response in renal tissue to improve acute kidney injury
期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 11, 页码: 17
作者:
Wu, Yong-Mei
;
Shi, Qing
;
Zhu, Peng-Fei
;
Ma, Hai-Jian
;
Cui, Shi-Chao
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/12/16
acute kidney injury
IKK/NF-kappa B
inflammation
macrophage
PI3K/PDK1/Akt
rhodomeroterpene
Structures of human mGlu2 and mGlu7 homo- and heterodimers
期刊论文
NATURE, 2021, 卷号: 594, 期号: 7864, 页码: 589-+
作者:
Du, Juan
;
Wang, Dejian
;
Fan, Hongcheng
;
Xu, Chanjuan
;
Tai, Linhua
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/08/17
Safety, Efficacy, and Biomarker Analysis of Pyrotinib in Combination with Capecitabine in HER2-Positive Metastatic Breast Cancer Patients: A Phase I Clinical Trial
期刊论文
CLINICAL CANCER RESEARCH, 2019, 卷号: 25, 期号: 17, 页码: 5212-5220
作者:
Li, Qiao
;
Guan, Xiuwen
;
Chen, Shanshan
;
Yi, Zongbi
;
Lan, Bo
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Synthesis and In Vitro Antibacterial Activity of Novel Naphthyridinone Derivatives
期刊论文
CHEMISTRYSELECT, 2019, 卷号: 4, 期号: 21, 页码: 6552-6556
作者:
Sun, Bin
;
Chen, Jianwei
;
Ye, Fei
;
Lu, Yaojia
;
Xu, Guiqing
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
antibacterial activity
C
violaceum ATCC 12472
naphthyridinone derivatives
quorum sensing inhibitory activity
synthesis
SOMCL-085, a novel multi-targeted FGFR inhibitor, displays potent anticancer activity in FGFR-addicted human cancer models
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 2, 页码: 243-250
作者:
Jiang, Xi-fei
;
Dai, Yang
;
Peng, Xia
;
Shen, Yan-yan
;
Su, Yi
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
human cancer
anticancer drug
SOMCL-085
receptor tyrosine kinase
FGFR
xenograft nude mouse model
Design, synthesis and biological evaluation of indolin-2-one-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase3 (FLT3)
期刊论文
European journal of medicinal chemistry, 2017, 卷号: 127, 页码: 72-86
作者:
Ma, Fei
;
Liu, Peng
;
Lei, Min
;
Liu, Jian
;
Wang, Hongtao
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Discovery of novel small molecule inhibitors of lysine methyltransferase G9a and their mechanism in leukemia cell lines
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 122, 页码: 382-393
作者:
Kondengaden, Shukkoor M.
;
Luo, Liu-fei
;
Huang, Kenneth
;
Zhu, Mengyuan
;
Zang, Lanlan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Lysine methyltransferase
G9a inhibitor
Leukemia
MALDI-TOF assay
Nuclear-targeting TAT-PEG-Asp(8)-doxorubicin polymeric nanoassembly to overcome drug-resistant colon cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 8, 页码: 1110-1120
作者:
Pan, Zhen-zhen
;
Wang, Hui-yuan
;
Zhang, Meng
;
Lin, Ting-ting
;
Zhang, Wen-yuan
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
doxorubicin
multidrug resistance
cell-penetrating peptide
poly(aspartic acid)
intranuclear delivery
nanoparticles
human colon cancer HCT8/ADR cells
A novel small-molecule compound targeting CD147 inhibits the motility and invasion of hepatocellular carcinoma cells
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 8, 页码: 9430-9448
作者:
Fu, Zhi-guang
;
Wang, Li
;
Cui, Hong-yong
;
Peng, Jian-long
;
Wang, Shi-jie
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
CD147
small molecule inhibitor
hepatocellular carcinoma cells
metastasis
dimerization
Study on formability of solid nanosuspensions during solidification: II novel roles of freezing stress and cryoprotectant property
期刊论文
International journal of pharmaceutics, 2014, 卷号: 475, 期号: 1-2, 页码: 35-48
作者:
Yue, Peng-Fei
;
Li, Gang
;
Dan, Ji-Xiu
;
Wu, Zhen-Feng
;
Wang, Chang-Hong
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
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