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科研机构
上海药物研究所 [1171]
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期刊论文 [1154]
会议论文 [16]
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2021 [111]
2020 [120]
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共1171条,第1-10条
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Enzalutamide-induced and PTH1R-mediated TGFBR2 degradation in osteoblasts confers resistance in prostate cancer bone metastases
期刊论文
CANCER LETTERS, 2022, 卷号: 525, 页码: 170-178
作者:
Su, Shang
;
Cao, Jingchen
;
Meng, Xiangqi
;
Liu, Ruihua
;
Vander Ark, Alexandra
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2022/01/04
Enzalutamide resistance
Prostate cancer
Bone microenvironment
TGFBR2
PTH1R
Nitrogenous Sesquiterpenoids from the South China Sea Nudibranch Hexabranchus sanguineus and Its Possible Sponge-Prey Acanthella cavernosa: Chiral Separation, Stereochemistry and Chemical Ecology
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2022, 卷号: 40, 期号: 2, 页码: 235-246
作者:
Shen, Shou-Mao
;
Zhang, Zai-Yong
;
Yao, Li-Gong
;
Wang, Jian-Rong
;
Guo, Yue-Wei
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/01/18
Hexabranchus sanguineus
Acanthella cavernosa
Chiral separation
Stereochemistry
Chemical ecology
Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy of orthotopic osteosarcoma (vol 417, 128103, 2021)
期刊论文
CHEMICAL ENGINEERING JOURNAL, 2022, 卷号: 428, 页码: 2
作者:
Geng, Huan
;
Zhou, Mengxue
;
Li, Bin
;
Liu, Liang
;
Yang, Xu
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/01/18
Cocktail polysaccharides isolated from Ecklonia kurome against the SARS-CoV-2 infection
期刊论文
CARBOHYDRATE POLYMERS, 2022, 卷号: 275, 页码: 8
作者:
Zhang, Shihai
;
Pei, Rongjuan
;
Li, Meixia
;
Su, Haixia
;
Sun, Hao
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2021/12/16
COVID-19
SARS-CoV-2
Angiotensin converting enzyme 2 (ACE2)
3CL protease
Ecklonia kurome Okam
Polysaccharide
Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Li, Teng-teng
;
Peng, Cheng
;
Wang, Ji-qiu
;
Xu, Zhi-jian
;
Su, Ming-bo
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/01/18
DPP4
distal mutation
enzymatic activity
molecular dynamics simulation
structure-function mechanism
Enones as Alkenyl Reagents via Ligand-Promoted C-C Bond Activation
期刊论文
ACS CATALYSIS, 2021, 页码: 82-88
作者:
Li, Hanyuan
;
Wang, Mei-Ling
;
Liu, Yu-Wen
;
Li, Ling-Jun
;
Xu, Hui
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/01/18
C-C bond activation
enone
olefination
Pd-catalyzed
late-stage diversification
Advancing COVID-19 diagnosis with privacy-preserving collaboration in artificial intelligence
期刊论文
NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 12, 页码: 1081-1089
作者:
Bai, Xiangd
;
Wang, Hanchen
;
Ma, Liya
;
Xu, Yongchao
;
Gan, Jiefeng
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2022/01/18
Picture-word order compound protein interaction: Predicting compound-protein interaction using structural images of compounds
期刊论文
JOURNAL OF COMPUTATIONAL CHEMISTRY, 2021, 页码: 10
作者:
Qian, Ying
;
Li, Xuelian
;
Wu, Jian
;
Zhou, Aimin
;
Xu, Zhijian
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/04
compound-protein interaction
convolutional neural network (CNN)
drug-drug interaction
image processing
structural images
M2 macrophage microvesicle-inspired nanovehicles improve accessibility to cancer cells and cancer stem cells in tumors
期刊论文
Journal of Nanobiotechnology, 2021, 卷号: 19, 期号: 1
作者:
Wang,Yuqi
;
Gong,Xiang
;
Li,Jie
;
Wang,Hong
;
Xu,Xiaoxuan
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/12/16
Cancer stem cells
Macrophage
Microvesicle
Nanoparticles
Cabazitaxel
Impurity Identification and Scale-Up of a Novel Glycopeptide Antibiotic
期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2390-2402
作者:
Jiao, Shang
;
Guan, Dongliang
;
Xu, Lili
;
Liu, Bo
;
Shi, Weiwei
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/01/18
glycopeptide antibiotics
impurity
analytical method
process optimization and development
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