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科研机构
上海药物研究所 [288]
内容类型
期刊论文 [282]
会议论文 [6]
发表日期
2022 [1]
2021 [42]
2020 [27]
2019 [21]
2018 [22]
2017 [17]
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Xishaglaucumins A-J, New Cembranoids with Anti-Inflammatory Activities from the South China Sea Soft Coral Sarcophyton glaucum
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2022, 卷号: 40, 期号: 1, 页码: 79-90
作者:
Li, Jin-Feng
;
Zeng, Yan-Bo
;
Li, Wang-Sheng
;
Luo, Hui
;
Zhang, Hai-Yan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/01/04
Sarcophyton glaucum
Cembranoids
Configuration determination
X-ray diffraction
NMR spectroscopy
GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhang, Qing
;
Chen, Lin-hai
;
Yang, Hui
;
Fang, You-chen
;
Wang, Si-wei
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/01/18
GPR84
medium chain fatty acid receptor
GPCR
inflammatory bowel diseases
ulcerative colitis
NLRP3 inflammasome
macrophages
Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14
作者:
Zhang, Chun
;
Sun, Yi-Tao
;
Gao, Li-Xin
;
Feng, Bo
;
Yan, Xue
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/01/18
Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Zou, Hui-xi
;
Zhang, Yu-feng
;
Zhong, Da-fang
;
Jiang, Yong
;
Liu, Fei
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/01/04
furmonertinib
autoinduction
food effect
alkaline phosphatase
body weight
pharmacokinetics
modeling and simulation
NSCLC
SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade
期刊论文
EMBO JOURNAL, 2021, 页码: 16
作者:
Wang, Xu
;
Ni, Jiahui
;
You, Yan
;
Feng, Guize
;
Zhang, Sulin
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/12/16
E-cadherin
IBD
intestinal barrier function
LPS release
SNX10
Arylketones as Aryl Donors in Palladium-Catalyzed Suzuki-Miyaura Couplings
期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 21, 页码: 8291-8295
作者:
Wang, Zhen-Yu
;
Ma, Biao
;
Xu, Hui
;
Wang, Xing
;
Zhang, Xu
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/01/04
Optimization and Development of a Scalable Palladium-Catalyzed C-H Activation Process for the Geometry-Selective Preparation of Kilograms of YLF466D, a Potent AMP-Activated Protein Kinase Activator
期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 10, 页码: 2260-2269
作者:
Yin, Jianpeng
;
Zhan, Desheng
;
Ma, Hui
;
Liu, Huanan
;
Yu, Lifang
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/12/16
YLF466D
AMPK activator
glucose metabolism
lipid metabolism
MIRI
domino reaction
C-H activation
Untargeted metabolomics coupled with chemometric analysis deducing robust markers for discrimination of processing procedures: Wine-processed Angelica sinensis as a case study
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 19
作者:
Yin, Haoran
;
Ni, Hui
;
Zhang, Linlin
;
Wu, Wenyong
;
Wu, Xingdong
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/12/01
Angelica sinensis
processing procedures
traditional Chinese medicine
untargeted metabolomics
wine-processing markers
Temperature-Controlled Divergent Synthesis of Tetrasubstituted Alkenes and Pyrrolo[1,2-a]indole Derivatives via Iridium Catalysis
期刊论文
ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2021, 页码: 14
作者:
Liu, Siyu
;
Mao, Hui
;
Qiao, Jin
;
Zhang, Xiaoning
;
Lu, Yangbin
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/11/04
Iridium
C-H activation
[3+2] annulation
Tetrasubstituted alkene
pyrrolo[1,2-a]indole
New formamidobisabolene-type sesquiterpenoids from a Hainan Sponge Halichondria sp.
期刊论文
TETRAHEDRON, 2021, 卷号: 96, 页码: 7
作者:
Chen, Bao
;
Li, Wang-Sheng
;
Gu, Yu-Cheng
;
Zhang, Hai-Yan
;
Luo, Hui
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/11/04
Sponge
Halichondria sp
Anti-inflammatory activity
Sesquiterpenes
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