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科研机构
中南大学 [7]
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期刊论文 [7]
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2018 [1]
2016 [2]
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2013 [1]
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Broad targeting of triptolide to resistance and sensitization for cancer therapy
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 104, 页码: 771-780
作者:
Hou, Zhen-yan
;
Tong, Xiao-pei
;
Peng, Yong-bo
;
Zhang, Bi-Kui*
;
Yan, Miao*
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/12/03
ABC
ATP-binding cassette
AKT
V-Akt murine thymoma viral oncogene homolog
ALDH1
aldehyde dehydrogenase 1
AR
androgen receptor
Bad
Bcl-2-associated death promoter
Bak
Bcl-2 homologous antagonist killer
Bax
Bcl-2-associated X protein
Bcl-2
B-cell lymphoma
Bcl-xL
Bcl-extra large
Bcl-xs
Bcl-extra short
BCRP
breast cancer resistance protein
Bid
BH3 interacting domain death agonist
Bik
Bcl-2-interacting killer
BNIP3
Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3
CAF
cancer-associated fibroblast
CAIX
carbonic anhydrase IX
cFLIP
cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein
ChIP
chromatin immunoprecipitation
CI
Combination Index
cIAP1/2
cellular IAP1/2
CML
chronic myelogenous leukemia
CSC
cancer stem cell
DISC
death-inducing signaling complex
DR
death receptor
DRI
Dose Reduction Index
ECM
extracellular matrix
EMT
epithelial-mesenchymal transition
EpCAM
epithelial cell adhesion molecule
GLUT
glucose transporter
GSK3β
glycogen synthase kinase-3β
HIF-1
hypoxia inducible factor-1
HSF1
heat shock factor 1
HSP
heat shock protein
IAP
inhibitor of apoptosis protein
JNK
c-JUN N-terminal kinase
MAPK
mitogen-activated protein kinase
Mcl-1
myeloid leukemia cell differentiation protein
MDM2
murine double minute 2
MDR
multidrug resistance
MKP
MAPK phosphatase
MRP1
multidrug resistance protein 1
NF-κB
nuclear factor-kappaB
pAkt
phosphor-Akt
PARP
poly ADP-ribose polymerase
P-gp
P-glycoprotein
PI3K-PTEN
phosphatidylinositol 3-kinase-phosphatase and tensin homolog
PKC
phosphorylated at Ser9 by protein kinase C
pp2A
protein phosphatase 2A
REST
repressor element-1 silencing transcription factor
SAR
structure-activity relationship
TAM
tumor-associated macrophage
TFIIH
transcription factor IIH
TKI
tyrosine kinase inhibitor
TM
tumor-microenvironment
TRAIL/Apo-2L
TNF-related apoptosis-inducing ligand
tRXRα
the N-terminal truncated form of the nuclear retinoid X receptor-α
TWHF
Tripterygium wilfordii Hook F
VEGF
vascular endothelial growth factor
XIAP
X-linked IAP
XPB
xerodermapigmentosum group B protein
Triptolide
Antineoplastic
Resistance
Sensitization
Mechanism
Bax/Bak activation in the absence of Bid, Bim, Puma, and p53
期刊论文
Cell Death & Disease, 2016, 卷号: 7, 期号: 6, 页码: e2266
作者:
Zhang, J.
;
Huang, K.
;
O'Neill, K. L.
;
Pang, X.
;
Luo, X.*
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/03
Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane
期刊论文
Genes and Development, 2016, 卷号: 30, 期号: 8, 页码: 973-988
作者:
O'Neill, Katelyn L
;
Huang, Kai
;
Zhang, Jingjing
;
Chen, Yi
;
Luo, Xu*
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
BH3-only
Bax/Bak activation
anti-apoptotic Bcl-2 proteins
outer mitochondrial membrane
High Bak Expression Is Associated with a Favorable Prognosis in Breast Cancer and Sensitizes Breast Cancer Cells to Paclitaxel
期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 9, 页码: e0138955
作者:
Luo, Yanwei
;
Wang, Xinye
;
Wang, Heran
;
Xu, Yang
;
Wen, Qiuyuan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/03
Breast cancer,Apoptosis,Cancer treatment,Metastasis,Small interfering RNAs,Cell cycle and cell division,Hyperexpression techniques,Cancer chemotherapy
Bax and Bak have critical roles in ischemic acute kidney injury in global and proximal tubule-specific knockout mouse models
期刊论文
Kidney International, 2013, 卷号: 84, 期号: 1, 页码: 138-148
作者:
Wei, Qingqing
;
Dong, Guie
;
Chen, Jian-Kang
;
Ramesh, Ganesan
;
Dong, Zheng*
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
apoptosis
mitochondria
necrosis
proximal tubule
renal ischemia
The p53-Bak apoptotic signaling axis plays an essential role in regulating differentiation of the ocular lens.
期刊论文
Current Molecular Medicine, 2012, 卷号: 12, 期号: 8, 页码: 901-916
作者:
Deng, M.
;
Chen, P.
;
Liu, F.
;
Fu, S.
;
Tang, H.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
Apoptosis
Bak
Cataract
Cell differentiation
Gene expression
Lens
Signaling pathway
Transcription regulation
Tumor suppressor
p53
MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression
期刊论文
Journal of Biological Chemistry, 2010, 卷号: 285, 期号: 28, 页码: 21496-21507
作者:
Zhou, Ming
;
Liu, Zixing
;
Zhao, Yuhua
;
Ding, Yan
;
Liu, Hao
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
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