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科研机构
上海药物研究所 [136]
内容类型
期刊论文 [116]
项目 [18]
会议论文 [2]
发表日期
2021 [12]
2020 [13]
2019 [16]
2018 [9]
2017 [14]
2016 [5]
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Chemistry [1]
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Scientific Research Project of Shanghai Municipal Health Commission on Traditional Chinese Medicine for Prevention and Treatment of COVID-19[2020XGKY07]
项目
项目编号: 2020XGKY07, 资助机构: Scientific Research Project of Shanghai Municipal Health Commission on Traditional Chinese Medicine for Prevention and Treatment of COVID-19, 2021-
-
收藏
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浏览/下载:18/0
  |  
提交时间:2021/12/01
Structure-Based Virtual Screening and Identification of Potential Inhibitors of SARS-CoV-2 S-RBD and ACE2 Interaction
期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 12
作者:
Xiong, Jiacheng
;
Xiang, Yusen
;
Huang, Ziming
;
Liu, Xiaohong
;
Wang, Mengge
收藏
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浏览/下载:42/0
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提交时间:2021/12/01
SARS-CoV-2
angiotensin-converting enzyme 2 (ACE2)
spike protein receptor-binding domain (S-RBD)
structure-based virtual screening
protein-protein interaction (PPI) inhibitors
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Wang, Lin
;
Wu, Yan
;
Yao, Sheng
;
Ge, Huan
;
Zhu, Ya
收藏
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浏览/下载:86/0
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提交时间:2021/11/04
SARS-CoV-2
natural products
virtual screening
spike protein
protein-protein interaction modulators
Blood Pyrrole-DNA Adducts Define the Early Tumorigenic Risk in Patients with Pyrrolizidine Alkaloid-Induced Liver Injury
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 2021, 卷号: 8, 期号: 7, 页码: 551-557
作者:
He, Yisheng
;
Zhang, Wei
;
Ma, Jiang
;
Xia, Qingsu
;
Song, Zijing
收藏
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浏览/下载:27/0
  |  
提交时间:2021/08/17
The inhibitory effect of 225 frequently-used traditional Chinese medicines for CYP3A4 metabolic enzyme by isoform-specific probe
期刊论文
FITOTERAPIA, 2021, 卷号: 152, 页码: 5
作者:
Wei, Wenlong
;
Li, Zhenwei
;
Li, Hao-jv
;
An, Yaling
;
Qu, Hua
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浏览/下载:33/0
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提交时间:2021/08/17
Inhibitory effect
Frequently-used traditional Chinese medicines
Isoform-specific probe
Multiscale modelling of cerebrovascular injury reveals the role of vascular anatomy and parenchymal shear stresses
期刊论文
SCIENTIFIC REPORTS, 2021, 卷号: 11, 期号: 1, 页码: 12
作者:
Khosroshahi, Siamak Farajzadeh
;
Yin, Xianzhen
;
Donat, Cornelius K.
;
McGarry, Aisling
;
Lopez, Maria Yanez
收藏
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浏览/下载:15/0
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提交时间:2021/08/17
Amygdala dynorphin/kappa opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zan, Gui-ying
;
Sun, Xiang
;
Wang, Yu-jun
;
Liu, Rui
;
Wang, Chen-yao
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浏览/下载:27/0
  |  
提交时间:2021/08/17
depression
social defeat stress
amygdala
κ
opioid receptor
dynorphin
c-fos
ERK
norBNI
Prevention of D-GalN/LPS-induced ALI by 18 beta-glycyrrhetinic acid through PXR-mediated inhibition of autophagy degradation
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 5, 页码: 13
作者:
Wu, Shouyan
;
Lu, Henglei
;
Wang, Wenjie
;
Song, Luyao
;
Liu, Meng
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浏览/下载:42/0
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提交时间:2021/08/17
Histone deacetylase inhibitor givinostat alleviates liver fibrosis by regulating hepatic stellate cell activation
期刊论文
MOLECULAR MEDICINE REPORTS, 2021, 卷号: 23, 期号: 5, 页码: 12
作者:
Huang, He-Ming
;
Zhou, Xiao-Ru
;
Liu, Yan-Jun
;
Fan, Shi-Jie
;
Liao, Li-Ping
收藏
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浏览/下载:46/0
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提交时间:2021/05/24
liver fibrosis
hepatic stellate cell
histone deacetylase inhibitor
epigenetics
givinostat
Gut Microbiota: Influence on Carcinogenesis and Modulation Strategies by Drug Delivery Systems to Improve Cancer Therapy
期刊论文
ADVANCED SCIENCE, 2021, 页码: 32
作者:
Zhu, Runqi
;
Lang, Tianqun
;
Yan, Wenlu
;
Zhu, Xiao
;
Huang, Xin
收藏
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浏览/下载:66/0
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提交时间:2021/05/24
cancer therapy
carcinogenesis
drug delivery system
gut microbiota
modulation
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