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浏览/检索结果: 共36条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway 期刊论文 ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298 作者:  Ding, Chunyong;  Song, Zilan;  Shen, Ancheng;  Chen, Tingting;  Zhang, Ao 收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 Immunotherapy  Anti-tumor  cGAS  STING  TBK1  Small molecule modulators   Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species-mediated apoptosis by targeting the electron transport chain 期刊论文 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2020, 卷号: 46, 期号: 6, 页码: 2137-2149 作者:  Pan, Lijia;  Nie, Litong;  Yao, Sheng;  Bi, Aiwei;  Ye, Yang 收藏  |  浏览/下载：26/0  |  提交时间：2020/12/24 neuroblastoma  bufalin  chemical proteomics  ETC  mitochondria   Mechanism and optimization of supramolecular complexation-enhanced fluorescence spectroscopy for the determination of SN-38 in plasma and cells 期刊论文 LUMINESCENCE, 2020, 页码: 12 作者:  Zhao, Kena;  Guo, Tao;  Sun, Xian;  Xiong, Ting;  Ren, Xiaohong 收藏  |  浏览/下载：47/0  |  提交时间：2020/12/24 cyclodextrins  inclusion complex  pharmacokinetics  SN‐  38  spectrofluorimetric  transfer   Clinical application of pyrrole-hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans 期刊论文 ARCHIVES OF TOXICOLOGY, 2020, 页码: 7 作者:  Ma, Jiang;  Zhang, Wei;  He, Yisheng;  Zhu, Lin;  Zhang, Chunyuan 收藏  |  浏览/下载：41/0  |  提交时间：2020/12/24 Pyrrolizidine alkaloids  Liver injury  Diagnostic biomarkers  Pyrrole-hemoglobin adducts  Pyrrole-plasma protein adducts   Helix Matrix Transformation Combined With Convolutional Neural Network Algorithm for Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry-Based Bacterial Identification 期刊论文 FRONTIERS IN MICROBIOLOGY, 2020, 卷号: 11, 页码: 10 作者:  Ling, Jin;  Li, Gaomin;  Shao, Hong;  Wang, Hong;  Yin, Hongrui 收藏  |  浏览/下载：124/0  |  提交时间：2020/12/24 matrix-assisted laser desorption ionization-time of flight mass spectrometry  bacterial identification  helix matrix transformation  convolutional neural network  algorithm study   Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Zhu, Lin;  Zhang, Chun-yuan;  Li, Dong-ping;  Chen, Hu-biao;  Ma, Jiang 收藏  |  浏览/下载：18/0  |  提交时间：2020/12/24 herb-induced liver injury  hepatic sinusoidal obstruction syndrome  pyrrolizidine alkaloids  Tu-San-Qi  Gynura japonica   SARS-CoV-2 and Three Related Coronaviruses Utilize Multipke ACE2 Orthologs and Are Potently Blocked by an Improved ACE2-Ig 期刊论文 JOURNAL OF VIROLOGY, 2020, 卷号: 94, 期号: 22, 页码: 14 作者:  Li, Yujun;  Wang, Haimin;  Tang, Xiaojuan;  Fang, Shisong;  Ma, Danting 收藏  |  浏览/下载：24/0  |  提交时间：2020/12/21 ACE2  ACE2-Ig  SARS-CoV-2  entry inhibitor  host range   Characterization of covalent binding of tyrosine kinase inhibitors to plasma proteins 期刊论文 DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 35, 期号: 5, 页码: 456-465 作者:  Liu, Xiaoyun;  Feng, Dan;  Zheng, Mingyue;  Cui, Yongmei;  Zhong, Dafang 收藏  |  浏览/下载：13/0  |  提交时间：2020/12/21 Covalent tyrosine kinase inhibitors  Covalent binding  Human serum albumin  Molecular docking  Quantitative calculations  Linear modeling  Species difference   An exosome-like programmable-bioactivating paclitaxel prodrug nanoplatform for enhanced breast cancer metastasis inhibition 期刊论文 BIOMATERIALS, 2020, 卷号: 257, 页码: 13 作者:  Wang, Kaiyuan;  Ye, Hao;  Zhang, Xuanbo;  Wang, Xia;  Yang, Bin 收藏  |  浏览/下载：42/0  |  提交时间：2020/12/24 Exosome membrane  Cucurbitacin B  Paclitaxel  Breast cancer metastasis  Programmable bioactivation   Systematic comparison of metabolic differences of Uncaria rhynchophylla in rat, mouse, dog, pig, monkey and human liver microsomes 期刊论文 ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 页码: 7 作者:  Li, Hao-Jv;  Wei, Wen-Long;  Li, Zhen-Wei;  Yao, Chang-Liang;  Wang, Meng-Yuan 收藏  |  浏览/下载：62/0  |  提交时间：2020/12/24 Uncaria rhynchophylla  Indole alkaloids  Mass defect filter  Time-staggered targeted ion lists  Metabolite identification  Liver microsomes