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Co-delivery of Cell-permeable Chimeric Apoptosis AVPIR(8) Peptide/p53 DNA for Cocktail Therapy 期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2013, 卷号: 23, 期号: 48, 页码: 6068-6075
作者:  Wang, Huiyuan;  Guo, Qianqian;  Jiang, Yifan;  Liu, Ergang;  Zhao, Yongxing
收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08
Oligomannurarate sulfate inhibits CXCL12/SDF-1-mediated proliferation and invasion of human tumor cells in vitro 期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 12, 页码: 1554-1559
作者:  Wen, Wei-wei;  Xie, Shao;  Xin, Xian-liang;  Geng, Mei-yu;  Ding, Jian
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08
Effect of surface charge of polymeric micelles on in vitro cellular uptake 期刊论文
CHINESE JOURNAL OF POLYMER SCIENCE, 2013, 卷号: 31, 期号: 9, 页码: 1299-1309
作者:  Zhou, Dan-hua;  Zhang, Jie;  Zhang, Guan;  Gan, Zhi-hua
收藏  |  浏览/下载：9/0  |  提交时间：2019/04/09
Targeted Drug Delivery Systems towards Cancer Therapy 会议论文
The 4th Asian Biomaterials Congress, 香港, 2013-06-26
沈折玉
收藏  |  浏览/下载：15/0  |  提交时间：2013/12/16
Mechanisms, function and clinical applications of DNp73 期刊论文
CELL CYCLE, 2013, 卷号: 12, 期号: 12, 页码: 1861-1867
作者:  Di, Cuixia;  Yang, Lina;  Zhang, Hong;  Ma, Xiaofei;  Zhang, Xin
收藏  |  浏览/下载：17/0  |  提交时间：2019/10/09
Mechanisms, function and clinical applications of DNp73 期刊论文
CELL CYCLE, 2013, 卷号: 12, 页码: 1861-1867
作者:  Di, Cuixia;  Yang, Lina;  Zhang, Hong;  Ma, Xiaofei;  Zhang, Xin
收藏  |  浏览/下载：13/0  |  提交时间：2018/07/05
Synthesis and structure-activity relationships study of cytotoxic bufalin 3-nitrogen-containing-ester derivatives 期刊论文
STEROIDS, 2013, 卷号: 78, 期号: 5, 页码: 508-512
作者:  Ma, Biao;  Xiao, Zhi-Yong;  Chen, Yi-Jia;  Lei, Min;  Meng, Yu-Hui
收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08
Involvement of the Mitochondrion-dependent and the Endoplasmic Reticulum Stress-signaling Pathways in Isoliquiritigenin-induced Apoptosis of HeLa Cell 期刊论文
BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 2013, 卷号: 26, 页码: 268-276
作者:  Yuan Xuan;  Zhang Bo;  Gan Lu;  Wang Zhen Hua;  Yu Ba Cui
收藏  |  浏览/下载：16/0  |  提交时间：2018/07/05
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
收藏  |  浏览/下载：26/0  |  提交时间：2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.  
Effects of carbon-ion beam or X-ray irradiation on anti-apoptosis Delta Np73 expression in HeLa cells 期刊论文
GENE, 2013, 卷号: 515, 页码: 208-213
作者:  Di, Cui-Xia;  Yang, Li-Na;  Zhang, Hong;  An, Li-Zhe;  Zhang, Xin
收藏  |  浏览/下载：21/0  |  提交时间：2018/07/05

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