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复旦大学上海医学院 [6]
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期刊论文 [42]
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First unequivocal identification of the critical acyl radicals from the anti- tuberculosis drug isoniazid and its hydrazide analogs by complementary applications of ESR spin-trapping and HPLC/MS methods
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 154, 页码: 1-8
作者:
Qin, Li
;
Huang, Chun-Hua
;
Mao, Li
;
Shao, Bo
;
Zhu, Ben-Zhan
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2021/09/14
Isoniazid
Hydrazides
Carbon-centered acyl radicals
ESR spin-trapping/HPLC/MS
N-tert-butyl-alpha-phenylnitrone (PBN)
NAD(+) adducts
锰催化氧化抗结核药物异烟肼的自由基机理研究
学位论文
北京: 中国科学院生态环境研究中心, 2020
作者:
秦丽
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  |  
浏览/下载:16/0
  |  
提交时间:2021/07/06
异烟肼和 肼类化合物 Mn( 氮中心自由基 酰碳自由基, 羟基自由 基 超氧阴离子
isoniazid And Hydrazine Derivatives, Mn(Iii), n Centered Radical, c Centered Acyl Radicals, Hydroxyl Radical, Superoxide
Vibrational spectra of pyrazinamide and isoniazid studied by terahertz spectroscopy and density functional theory
期刊论文
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2020, 卷号: 228, 页码: 11
作者:
Liang, Jie
;
Zhang, Xiaoxuan
;
Wang, Nan
;
Chang, Tianying
;
Cui, Hong-Liang
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/08/24
Terahertz time-domain spectroscopy (THz-TDS)
Anti-tuberculosis
Pyrazinamide
Isoniazid
Density functional theory (DFT)
Molecular mechanism for the activation of the anti-tuberculosis drug isoniazid by Mn(III): First detection and unequivocal identification of the critical N-centered isoniazidyl radical and its exact location
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2019, 卷号: 143, 页码: 232-239
作者:
Qin, Li
;
Huang, Chun-Hua
;
Xu, Dan
;
Xie, Lin-Na
;
Shao, Jie
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/09/10
Isoniazid
Mn(III)(Acetate) 3
Isoniazidyl radical
Distal-nitrogen of the hydrazine group
Diisonicotinyl hydrazine
Spoligotyping, phenotypic and genotypic characterization of katG, rpoB gene of M. tuberculosis isolates from Sahariya tribe of Madhya Pradesh India
期刊论文
JOURNAL OF INFECTION AND PUBLIC HEALTH, 2019, 卷号: 12, 期号: 3
作者:
Gupta, Rahul
;
Amrathlal, Rabbind Singh
;
Prakash, Ravi
;
Jain, Sanjay
;
Tiwari, Pramod K.
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
Isoniazid resistance
Multi-drug resistance
M. tuberculosis
Sahariya tribe
Spoligotyping
Dysregulation of Na+-taurocholate co-transporting polypeptide (NTCP) plays a vital role in isoniazid-induced HepG2 cells apoptosis
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2018, 卷号: 11, 期号: 8
作者:
Zhang, Yue-Ming
;
Zhang, Si-Xi
;
Qu, Xiao-Yu
;
Tao, Li-Na
;
Gao, Huan
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Isoniazid
Na+-taurocholate co-transporting polypeptide
HepG2 cells
apoptosis
hepatocyte nuclear factor 4 alpha
peroxisome proliferator activated receptor y coactivator 1 alpha
Dysregulation of BSEP and MRP2 May Play an Important Role in Isoniazid-Induced Liver Injury via the SIRT1/FXR Pathway in Rats and HepG2 Cells
期刊论文
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2018, 卷号: 41, 期号: 8
作者:
Gao, Huan
;
Song, Yanqing
;
Tao, Lina
;
Zhai, Jinghui
;
Zhang, Sixi
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/05
isoniazid
liver injury
bile salt export pump
multidrug resistance protein 2
farnesoid X receptor
Sirtuin 1
Pharmacokinetics of isoniazid and rifampicin-loaded bovine serum albumin nanoparticles in rabbits
期刊论文
Latin American Journal of Pharmacy, 2018, 卷号: 37, 页码: 1938-1944
作者:
Ge, Zhaohui
;
Ma, Rong
;
Xu, Guangxian
;
Bai, Jing
;
Liang, Siming
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  |  
浏览/下载:3/0
  |  
提交时间:2019/11/19
Albumin
Isoniazid
Nanoparticles
Pharmacokinetic processes
Rifampicin
Development and In Vitro Release of Isoniazid and Rifampicin-Loaded Bovine Serum Albumin Nanoparticles
期刊论文
MEDICAL SCIENCE MONITOR, 2018, 卷号: 24, 页码: 473-478
作者:
Ge, Zhaohui
;
Ma, Rong
;
Xu, Guangxian
;
Chen, Zhen
;
Zhang, Dangfeng
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/26
Isoniazid
In Vitro
Nanoparticles
Albumins
Detection of novel mutations associated with independent and cross-resistance to isoniazid and prothionamide in Mycobacterium tuberculosis clinical isolates.
期刊论文
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2018
作者:
Surineni Goverdhan
;
Zhong Nanshan
;
Hameed H M Adnan
;
Chhotaray Chiranjibi
;
Cai Xingshan
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/04/24
Cross-resistance
Isoniazid
Multidrug-resistant
Mutation
Mycobacterium
tuberculosis,
Prothionamide
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