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CORC

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Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity 期刊论文
XENOBIOTICA, 2021, 页码: 13
作者:  Sun, Dongxue;  Gao, Xiaoxia;  Wang, Qiao;  Krausz, Kristopher W.;  Fang, Zhongze
收藏  |  浏览/下载：48/0  |  提交时间：2021/11/04
Itraconazole and rifampicin, as CYP3A modulators but not P-gp modulators, affect the pharmacokinetics of almonertinib and active metabolite HAS-719 in healthy volunteers 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Liu, Lu;  Li, Wei;  Yang, Le;  Guo, Zi-tao;  Xue, Hao
收藏  |  浏览/下载：78/0  |  提交时间：2021/08/17
In Vivo Efficacy and Metabolism of the Antimalarial Cycleanine and Improved In Vitro Antiplasmodial Activity of Semisynthetic Analogues 期刊论文
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 卷号: 65, 期号: 2, 页码: 11
作者:  Uche, Fidelia Ijeoma;  Guo, Xiaozhen;  Okokon, Jude;  Ullah, Imran;  Horrocks, Paul
收藏  |  浏览/下载：26/0  |  提交时间：2021/05/24
Design of G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) soft drugs with reduced gallbladder-filling effects 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 12
作者:  Han, Fanghui;  Ning, Mengmeng;  Cao, Hua;  Ye, Yangliang;  Feng, Ying
收藏  |  浏览/下载：32/0  |  提交时间：2020/12/21
Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans: major enzymes and transporters identified 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:  Pan, Lu-lu;  Yang, Yong;  Hui, Min;  Wang, Shuo;  Li, Cui-yun
收藏  |  浏览/下载：82/0  |  提交时间：2020/12/24
Alflutinib (AST2818), primarily metabolized by CYP3A4, is a potent CYP3A4 inducer 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:  Liu, Xiao-yun;  Guo, Zi-tao;  Chen, Zhen-dong;  Zhang, Yi-fan;  Zhou, Jia-lan
收藏  |  浏览/下载：76/0  |  提交时间：2020/07/01
Biotransformation Mechanism of Pesticides by Cytochrome P450: A DFT Study on Dieldrin 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2020, 卷号: 33, 期号: 6, 页码: 1442-1448
作者:  Chai, Lihong;  Ji, Shujing;  Zhang, Shubin;  Yu, Haiying;  Zhao, Meirong
收藏  |  浏览/下载：24/0  |  提交时间：2020/08/07
Current trends in drug metabolism and pharmacokinetics 期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1113-1144
作者:  Li, Yuhua;  Meng, Qiang;  Yang, Mengbi;  Liu, Dongyang;  Hou, Xiangyu
收藏  |  浏览/下载：33/0  |  提交时间：2020/07/01
Enhanced Anti-diabetic Effect of Berberine Combined With Timosaponin B2 in Goto-Kakizaki Rats, Associated With Increased Variety and Exposure of Effective Substances Through Intestinal Absorption 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 15
作者:  Tian, Xiaoting;  Liu, Fang;  Li, Zhixiong;  Lin, Yunfei;  Liu, Huan
收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01
Safety Assessment of Compounds after In Vitro Metabolic Conversion Using Zebrafish Eleuthero Embryos 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 卷号: 20, 期号: 7
作者:  Ny, Annelii;  Giusti, Arianna;  Xuan-Bac Nguyen;  Kislyuk, Stanislav;  Mignot, Melanie
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/05

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