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科研机构
北京大学 [7]
长春应用化学研究所 [4]
化学研究所 [2]
清华大学 [1]
上海药物研究所 [1]
中国科学院大学 [1]
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期刊论文 [22]
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2018 [2]
2017 [2]
2016 [4]
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Synthesis and In Vitro Antitumor Activity of Novel Bivalent -Carboline-3-carboxylic Acid Derivatives with DNA as a Potential Target
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 10
作者:
Gu, Hongling
;
Li, Na
;
Dai, Jiangkun
;
Xi, Yaxi
;
Wang, Shijun
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
bivalent -carbolines
antitumor
apoptosis
DNA-binding affinity
bcl-2
Two amino acid changes in the R3 repeat cause functional divergence of two clustered MYB10 genes in peach
期刊论文
PLANT MOLECULAR BIOLOGY, 2018, 卷号: 98, 期号: 1-2, 页码: 169-183
作者:
Han, Yuepeng
;
Jiang, Quan
;
Wang, Lu
;
Ogutu, Collins
;
Zhao, Jianbo
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  |  
浏览/下载:30/0
  |  
提交时间:2018/12/29
Prunus
Anthocyanin coloration
R2R3-MYB TF
bHLH gene
DNA-binding affinity
Site-directed mutation
Exploration of a multi-target ligand, dehydroevodiamine, for the recognition of three G-quadruplexes in c-Myb proto-oncogene by ESI-MS
期刊论文
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2017
Li, Fangyuan
;
Zhou, Jiang
;
Xu, Ming
;
Yuan, Gu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/12/03
c-Myb
G-quadruplex
ESI-MS
Dehydroevodiamine
MASS-SPECTROMETRY
BINDING-AFFINITY
P1 PROMOTER
DNA
TRANSCRIPTION
DERIVATIVES
SELECTIVITY
ONCOGENE
UPSTREAM
REGION
Effects of mutants in bHLH region on structure stability and protein-DNA binding energy in DECs
期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2017, 卷号: 35, 期号: 9, 页码: 1849-1862
作者:
Kong, Yi
;
Wang, Zhen
;
Jia, Yanfei
;
Li, Ping
;
Hao, Shuhua
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  |  
浏览/下载:7/0
  |  
提交时间:2019/12/12
DNA-binding affinity
DEC1/2
protein comparative modeling
molecular
dynamics simulation
Determination of the platelet-derived growth factor BB by a competitive thrombin-linked aptamer-based Fluorometric assay
期刊论文
MICROCHIMICA ACTA, 2016, 卷号: 183, 期号: 12, 页码: 3229-3235
作者:
Guo, Limin
;
Zhao, Qiang
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  |  
浏览/下载:260/0
  |  
提交时间:2017/03/27
Aptasensor
Fluorescence
Enzyme label
Microplate assay
Microtiter plate
Fluorogenic enzyme substrate
Serine protease
DNA probe
Affinity binding
Dual functional probe
Displacement
Indirect analysis
High DNA-Binding Affinity and Gene-Transfection Efficacy of Bioreducible Cationic Nanomicelles with a Fluorinated Core
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 卷号: 55, 期号: 2, 页码: 755-759
作者:
Wang, Long-Hai
;
Wu, De-Cheng
;
Xu, Hang-Xun
;
You, Ye-Zi
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  |  
浏览/下载:23/0
  |  
提交时间:2016/03/14
biotechnology
DNA-binding affinity
gene delivery
nanomicelles
nanostructures
High DNA-Binding Affinity and Gene-Transfection Efficacy of Bioreducible Cationic Nanomicelles with a Fluorinated Core
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 卷号: 55, 期号: 2, 页码: 755-759
作者:
Wang, Long-Hai
;
Wu, De-Cheng
;
Xu, Hang-Xun
;
You, Ye-Zi
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2016/03/14
biotechnology
DNA-binding affinity
gene delivery
nanomicelles
nanostructures
Recognition of an important G-quadruplex in the HIV-1 promoter with natural small molecules
期刊论文
CANADIAN JOURNAL OF CHEMISTRY, 2016
Wang, Weixuan
;
Sui, Yang
;
Zhang, Lulu
;
Tan, Wei
;
He, Xiangwei
;
Xie, Xiangming
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/12/03
G-quadruplex
binding affinity
ESI mass spectrometry
DMS footprinting
circular dichroism
NUCLEIC-ACIDS
DRUG DESIGN
DNA
SEQUENCES
TOPOLOGY
DATABASE
TARGETS
LIGAND
Photoaffinity labeling of transcription factors by DNA-templated crosslinking
期刊论文
chemical science, 2015
Liu, Ying
;
Zheng, Wenlu
;
Zhang, Wan
;
Chen, Nan
;
Liu, Yang
;
Chen, Li
;
Zhou, Xiaozhou
;
Chen, Xingshuo
;
Zheng, Haifeng
;
Li, Xiaoyu
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/10
NF-KAPPA-B
ENCODED CHEMICAL LIBRARIES
PROTEIN-DNA
BINDING-PROTEINS
GENE-EXPRESSION
GEL-ELECTROPHORESIS
PHOTOCROSS-LINKING
COMPLEX REVEALS
ASSAY
AFFINITY
The genomic DNA immobilization on microcrystalline cellulose and its application to separate DNA-binding proteins from kumquat (Fortunella margarita Swingle).
期刊论文
Protein and Peptide Letters, 2014, 卷号: 21, 期号: 12, 页码: 1240-1246
作者:
Yang, Hua
;
Li, Huang
;
Guo, Chun
;
Li, Meng-Yun
;
Rao, Li-Qun
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
Affinity chromatography
DNA duplex formation
DNA immobilization
DNA-binding proteins
Microcrystalline cellulose
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